5FJS

Bacterial beta-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004348	molecular_function	glucosylceramidase activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0006680	biological_process	glucosylceramide catabolic process
A	0008422	molecular_function	beta-glucosidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046872	molecular_function	metal ion binding
B	0004348	molecular_function	glucosylceramidase activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0005975	biological_process	carbohydrate metabolic process
B	0006680	biological_process	glucosylceramide catabolic process
B	0008422	molecular_function	beta-glucosidase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 1804

Chain	Residue
B	ASP575
B	ASP577
B	ASP579
B	ILE581
B	ASP583

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 1804

Chain	Residue
A	ASP583
A	ASP575
A	ASP577
A	ASP579
A	ILE581

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