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5FJS

Bacterial beta-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004348molecular_functionglucosylceramidase activity
A0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
A0005975biological_processcarbohydrate metabolic process
A0006680biological_processglucosylceramide catabolic process
A0008422molecular_functionbeta-glucosidase activity
A0016020cellular_componentmembrane
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0046872molecular_functionmetal ion binding
B0004348molecular_functionglucosylceramidase activity
B0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
B0005975biological_processcarbohydrate metabolic process
B0006680biological_processglucosylceramide catabolic process
B0008422molecular_functionbeta-glucosidase activity
B0016020cellular_componentmembrane
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA B 1804
ChainResidue
BASP575
BASP577
BASP579
BILE581
BASP583

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 1804
ChainResidue
AASP583
AASP575
AASP577
AASP579
AILE581

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PDB entries from 2024-06-12

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