Author results

3NXF
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ROBUST COMPUTATIONAL DESIGN, OPTIMIZATION, AND STRUCTURAL CHARACTERIZATION OF RETROALDOL ENZYMES
Descriptor:Retro-Aldolase, SULFATE ION
Authors:Althoff, E.A., Jiang, L., Wang, L., Lassila, J.K., Moody, J., Bolduc, J., Wang, Z.Z., Smith, M., Hari, S., Herschlag, D., Stoddard, B.L., Baker, D.
Deposit date:2010-07-13
Release date:2011-06-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design.
J.Mol.Biol., 415, 2012
3O6Y
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ROBUST COMPUTATIONAL DESIGN, OPTIMIZATION, AND STRUCTURAL CHARACTERIZATION OF RETROALDOL ENZYMES
Descriptor:Retro-Aldolase, SULFATE ION
Authors:Althoff, E.A., Wang, L., Jiang, L., Moody, J., Bolduc, J., Lassila, J.K., Wang, Z.Z., Smith, M., Hari, S., Herschlag, D., Stoddard, B.L., Baker, D.
Deposit date:2010-07-29
Release date:2011-06-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design.
J.Mol.Biol., 415, 2012
3UD6
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STRUCTURAL ANALYSES OF COVALENT ENZYME-SUBSTRATE ANALOGUE COMPLEXES REVEAL STRENGTHS AND LIMITATIONS OF DE NOVO ENZYME DESIGN
Descriptor:RETRO-ALDOLASE, 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, SULFATE ION
Authors:Baker, D., Stoddard, B.L., Althoff, E.A., Wang, L., Jiang, L., Moody, J., Bolduc, J., Lassila, J., Hilvert, D.
Deposit date:2011-10-27
Release date:2011-11-23
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design.
J.Mol.Biol., 415, 2012
4YXX
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 6 REPEATS
Descriptor:dTor_6x35L
Authors:Doyle, L., Bolduc, J., Stoddard, B.L., Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4IWW
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COMPUTATIONAL DESIGN OF AN UNNATURAL AMINO ACID METALLOPROTEIN WITH ATOMIC LEVEL ACCURACY
Descriptor:Unnatural Amino Acid Mediated Metalloprotein, SULFATE ION, COBALT (II) ION
Authors:Mills, J., Bolduc, J., Khare, S., Stoddard, B., Baker, D.
Deposit date:2013-01-24
Release date:2013-08-21
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational design of an unnatural amino Acid dependent metalloprotein with atomic level accuracy.
J.Am.Chem.Soc., 135, 2013
4IX0
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COMPUTATIONAL DESIGN OF AN UNNATURAL AMINO ACID METALLOPROTEIN WITH ATOMIC LEVEL ACCURACY
Descriptor:Unnatural Amino Acid Mediated Metalloprotein, NICKEL (II) ION, SULFATE ION
Authors:Mills, J., Bolduc, J., Khare, S., Stoddard, B., Baker, D.
Deposit date:2013-01-24
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational design of an unnatural amino Acid dependent metalloprotein with atomic level accuracy.
J.Am.Chem.Soc., 135, 2013
4YXY
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 9 REPEATS; TWO LINKED RINGS OF 12 REPEATS EACH STRUCTURE
Descriptor:dTor_9x31L
Authors:Doyle, L., Stoddard, B.L., Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXZ
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 9 REPEATS
Descriptor:dTor_9x31L
Authors:Doyle, L., Stoddard, B.L., Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY2
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 3 REPEATS IN SPACE GROUP P212121
Descriptor:dTor_3x33L, SODIUM ION
Authors:Hallinan, J.P., Bradley, P., Stoddard, B.L.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY5
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 3 REPEATS IN SPACE GROUP P43212
Descriptor:dTor_3x33L
Authors:Hallinan, J.P., Bradley, P., Stoddard, B.L.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
5BYO
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COMPUTATIONALLY DESIGNED LEFT-HANDED ALPHA/ALPHA TOROID WITH 12 REPEATS
Descriptor:dTor_12x31L
Authors:Doyle, L., Stoddard, B.L., Bradley, P.
Deposit date:2015-06-10
Release date:2015-12-16
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015