Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3L4C
DownloadVisualize
BU of 3l4c by Molmil
Structural basis of membrane-targeting by Dock180
Descriptor: BETA-MERCAPTOETHANOL, Dedicator of cytokinesis protein 1
Authors:Premkumar, L, Bobkov, A.A, Patel, M, Jaroszewski, L, Bankston, L.A, Stec, B, Vuori, K, Cote, J.-F, Liddington, R.C.
Deposit date:2009-12-18
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs).
J.Biol.Chem., 285, 2010
6X7I
DownloadVisualize
BU of 6x7i by Molmil
Structure of the C-terminal domain of BCL-XL in membrane
Descriptor: Bcl-2-like protein 1
Authors:Yao, Y, Tian, Y, Marassi, F.M.
Deposit date:2020-05-30
Release date:2020-07-01
Last modified:2024-05-15
Method:SOLID-STATE NMR, SOLUTION NMR
Cite:Conformational States of the Cytoprotective Protein Bcl-xL.
Biophys.J., 119, 2020
8VHE
DownloadVisualize
BU of 8vhe by Molmil
Crystal Structure of Human IDH1 R132Q in Complex with NADPH-TCEP Adduct
Descriptor: 3,3',3''-({(4R)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1,4-dihydropyridin-4-yl}-lambda~5~-phosphanetriyl)tripropanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHB
DownloadVisualize
BU of 8vhb by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Alpha-Ketoglutarate
Descriptor: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, 2-OXOGLUTARIC ACID, CALCIUM ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VH9
DownloadVisualize
BU of 8vh9 by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH
Descriptor: CITRIC ACID, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHD
DownloadVisualize
BU of 8vhd by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Isocitrate
Descriptor: CALCIUM ION, GLYCEROL, IODIDE ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHA
DownloadVisualize
BU of 8vha by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Alpha-Ketoglutarate
Descriptor: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, 2-OXOGLUTARIC ACID, CALCIUM ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHC
DownloadVisualize
BU of 8vhc by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH
Descriptor: GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
1ST6
DownloadVisualize
BU of 1st6 by Molmil
Crystal structure of a cytoskeletal protein
Descriptor: Vinculin
Authors:Bakolitsa, C, Liddington, R.C.
Deposit date:2004-03-25
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for vinculin activation at sites of cell adhesion.
Nature, 430, 2004
3DYJ
DownloadVisualize
BU of 3dyj by Molmil
Crystal Structure of the R11R12 Domains of Talin
Descriptor: TALIN-1
Authors:Gingras, A.R, Joyce, M.G, Critchley, D.R, Emsley, J.
Deposit date:2008-07-28
Release date:2009-01-27
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural determinants of integrin binding to the talin rod
J.Biol.Chem., 284, 2009
7KJZ
DownloadVisualize
BU of 7kjz by Molmil
crystal structure of PLEKHA7 PH domain biding inositol-tetraphosphate
Descriptor: 1,2-ETHANEDIOL, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Pleckstrin homology domain-containing family A member 7
Authors:Marassi, F.M, Aleshin, A.E, Liddington, R.C.
Deposit date:2020-10-26
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
7KK7
DownloadVisualize
BU of 7kk7 by Molmil
crystal structure of ligand-free PLEKHA7 PH domain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Pleckstrin homology domain-containing family A member 7
Authors:Marassi, F.M, Aleshin, A.E, Liddington, R.C.
Deposit date:2020-10-27
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
7KJO
DownloadVisualize
BU of 7kjo by Molmil
crystal structure of PLEKHA7 PH domain biding SO4
Descriptor: GLYCEROL, Pleckstrin homology domain-containing family A member 7, SULFATE ION
Authors:Marassi, F.M, Aleshin, A.E, Liddington, R.C.
Deposit date:2020-10-26
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
5KHQ
DownloadVisualize
BU of 5khq by Molmil
Rasip1 RA domain
Descriptor: GLYCEROL, Ras-interacting protein 1
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
5KHO
DownloadVisualize
BU of 5kho by Molmil
Rasip1 RA domain in complex with Rap1B
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Gingras, A.R.
Deposit date:2016-06-15
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
Structure, 24, 2016
5JNS
DownloadVisualize
BU of 5jns by Molmil
Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate
Descriptor: DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNV
DownloadVisualize
BU of 5jnv by Molmil
Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with HEPES
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNT
DownloadVisualize
BU of 5jnt by Molmil
Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNR
DownloadVisualize
BU of 5jnr by Molmil
Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A
Descriptor: Low molecular weight phosphotyrosine protein phosphatase
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNW
DownloadVisualize
BU of 5jnw by Molmil
Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with vanadate and uncompetitive inhibitor
Descriptor: 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile, Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNU
DownloadVisualize
BU of 5jnu by Molmil
Crystal structure of mouse Low-Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with phosphate
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION
Authors:Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N.
Deposit date:2016-04-30
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.535 Å)
Cite:Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon