Author results

1MHM
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CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE DECARBOXYLASE FROM POTATO
Descriptor:S-adenosylmethionine decarboxylase
Authors:Bennett, E.M., Ekstrom, J.L., Pegg, A.E., Ealick, S.E.
Deposit date:2002-08-20
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Monomeric S-Adenosylmethionine Decarboxylase from Plants Provides an Alternative to Putrescine Stimulation
Biochemistry, 41, 2002
1PK7
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH ADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, ADENOSINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK9
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 2-FLUOROADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PKE
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 2-FLUORO-2'-DEOXYADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR0
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, INOSINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR1
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH FORMYCIN B AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, FORMYCIN B
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR2
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-[2-DEOXYRIBOFURANOSYL]-6-METHYLPURINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR4
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-RIBOFURANOSYL-6-METHYLTHIOPURINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR5
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 7-DEAZAADENOSINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR6
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-XYLOFURANOSYLADENINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PW7
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-ARABINOFURANOSYLADENINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-30
Release date:2003-11-25
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1OTX
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PURINE NUCLEOSIDE PHOSPHORYLASE M64V MUTANT
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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NATIVE PNP +ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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NATIVE PNP +TALO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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M64V PNP +TALO
Descriptor:Purine nucleoside phosphorylase, 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OV6
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M64V PNP + ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-25
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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M64V PNP +MEPDR
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-26
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1JXH
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM
Descriptor:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION
Authors:Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
Deposit date:2001-09-07
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1JXI
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
Descriptor:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
Authors:Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
Deposit date:2001-09-07
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1MSV
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THE S68A S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME PROCESSING MUTANT.
Descriptor:S-adenosylmethionine decarboxylase proenzyme, 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Tolbert, W.D., Zhang, Y., Bennett, E.M., Cottet, S.E., Ekstrom, J.L., Pegg, A.E., Ealick, S.E.
Deposit date:2002-09-19
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of Human S-Adenosylmethionine Decarboxylase Proenzyme Processing as Revealed by the Structure of the S68A Mutant.
Biochemistry, 42, 2003
1R9G
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THREE-DIMENSIONAL STRUCTURE OF YAAE FROM BACILLUS SUBTILIS
Descriptor:Hypothetical protein yaaE
Authors:Bauer, J.A., Bennett, E.M., Begley, T.P., Ealick, S.E.
Deposit date:2003-10-29
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional Structure of YaaE from Bacillus subtilis, a Glutaminase Implicated in Pyridoxal-5'-phosphate Biosynthesis.
J.Biol.Chem., 279, 2004
1T4A
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STRUCTURE OF B. SUBTILIS PURS C2 CRYSTAL FORM
Descriptor:PurS
Authors:Anand, R., Hoskins, A.A., Bennett, E.M., Sintchak, M.D., Stubbe, J., Ealick, S.E.
Deposit date:2004-04-28
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex.
Biochemistry, 43, 2004
4FUL
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PI3 KINASE GAMMA BOUND TO A PYRMIDINE INHIBITOR
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, 4-({4-[3-(piperidin-1-ylcarbonyl)phenyl]pyrimidin-2-yl}amino)benzenesulfonamide
Authors:Gopalsamy, A., Bennett, E.M., Shi, M., Zhang, W.G., Bard, J., Yu, K.
Deposit date:2012-06-28
Release date:2012-10-17
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Identification of pyrimidine derivatives as hSMG-1 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
1TWJ
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CRYSTAL STRUCTURE OF B. SUBTILIS PURS P21 CRYSTAL FORM
Descriptor:Hypothetical UPF0062 protein yexA
Authors:Anand, R., Ealick, S.E., Hoskins, A.A., Stubbe, J.
Deposit date:2004-07-01
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Model for the Bacillus subtilis Formylglycinamide Ribonucleotide Amidotransferase Multiprotein Complex
Biochemistry, 43, 2004