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4ZFQ
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BU of 4zfq by Molmil
Structure of M. tuberculosis (3,3) L,D-Transpeptidase, LdtMt5. (Meropenen-adduct form)
Descriptor: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, DI(HYDROXYETHYL)ETHER, L,D-transpeptidase 5
Authors:Basta, L, Ghosh, A, Lamichhane, G, Bianchet, M.A.
Deposit date:2015-04-21
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
4Z7A
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BU of 4z7a by Molmil
Structural and biochemical characterization of a non-functionally redundant M. tuberculosis (3,3) L,D-Transpeptidase, LdtMt5.
Descriptor: ACETYL GROUP, DI(HYDROXYETHYL)ETHER, Mycobacterium tuberculosis (3,3)L,D-Transpeptidase type 5, ...
Authors:Basta, L, Ghosh, A, Pan, Y, Jakoncic, J, Lloyd, E, Townsend, G, Lamichhane, G, Bianchet, M.A.
Deposit date:2015-04-06
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
6BOI
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BU of 6boi by Molmil
Crystal Structure of LdtMt2 (56-408) with a panipenem adduct at the active site cysteine-354
Descriptor: (3S,5R)-5-[(2R,3R)-1,3-dihydroxybutan-2-yl]-3-({(3R)-1-[(1E)-ethanimidoyl]pyrrolidin-3-yl}sulfanyl)-L-proline, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Saavedra, H, Bianchet, M.A.
Deposit date:2017-11-20
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structures and Mechanism of Inhibition of Mycobacterium tuberculosis L,D-transpeptidase 2 by Panipenem
To Be Published
5D7H
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BU of 5d7h by Molmil
X-RAY CRYSTAL STRUCTURE OF L,D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: GLYCEROL, L,D-transpeptidase 2, SULFATE ION
Authors:Saavedra, H, Basta, L.A, Lamichhane, G, Bianchet, M.A.
Deposit date:2015-08-13
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.
BMC Biochem., 18, 2017

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