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3RPB
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BU of 3rpb by Molmil
THE C2B-DOMAIN OF RABPHILIN: STRUCTURAL VARIATIONS IN A JANUS-FACED DOMAIN
Descriptor: RABPHILIN 3-A
Authors:Ubach, J, Garcia, J, Nittler, M.P, Sudhof, T.C, Rizo, J.
Deposit date:1999-04-19
Release date:1999-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Janus-faced C2B domain of rabphilin.
Nat.Cell Biol., 1, 1999
6HZV
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BU of 6hzv by Molmil
HUMAN JAK3 IN COMPLEX WITH LASW959 PROTEIN IN COMPLEX WITH LIGAND
Descriptor: 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile, Tyrosine-protein kinase JAK3
Authors:Lozoya, E, Segarra, V, Bach, J, Jestel, A, Lammens, A, Blaesse, M.
Deposit date:2018-10-24
Release date:2019-10-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.
J.Med.Chem., 62, 2019
6HZU
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BU of 6hzu by Molmil
HUMAN JAK1 IN COMPLEX WITH LASW1393
Descriptor: 2-[4-[8-oxidanylidene-2-[(~{E})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{H}-purin-9-yl]cyclohexyl]ethanenitrile, Tyrosine-protein kinase JAK1
Authors:Lozoya, E, Segarra, V, Bach, J, Jestel, A, Lammens, A, Blaesse, M.
Deposit date:2018-10-24
Release date:2019-10-23
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.
J.Med.Chem., 62, 2019
5AEN
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BU of 5aen by Molmil
Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine
Descriptor: IMIDAZOLE, LEUKOTRIENE A-4 HYDROLASE, N,N-dimethyl-2-(4-phenoxyphenoxy)ethanamine, ...
Authors:Moser, D, Wittmann, S.K, Kramer, J, Blocher, R, Achenbach, J, Pogoryelov, D, Proschak, E.
Deposit date:2015-01-06
Release date:2015-02-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.864 Å)
Cite:Peng: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation and Virtual Screening for Novel Ligands of Lta4H.
J.Chem.Inf.Model., 55, 2015
3CGM
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BU of 3cgm by Molmil
Crystal structure of thermophilic SlyD
Descriptor: GLYCEROL, NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase, ...
Authors:Loew, C, Neumann, P, Stubbs, M.T, Balbach, J.
Deposit date:2008-03-06
Release date:2009-03-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
J.Mol.Biol., 398, 2010
2RMY
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BU of 2rmy by Molmil
Structure of the N-terminal BARpeptide in SDS micelles
Descriptor: Myc box-dependent-interacting protein 1
Authors:Loew, C, Weininger, U, Balbach, J.
Deposit date:2007-12-03
Release date:2008-10-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Biophys.J., 95, 2008
3LUO
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BU of 3luo by Molmil
Crystal Structure and functional characterization of the thermophilic prolyl isomerase and chaperone SlyD
Descriptor: Peptidyl-prolyl cis-trans isomerase, Suc-Ala-Leu-Pro-Phe-pNA, ZINC ION
Authors:Loew, C, Neumann, P, Weininger, U, Stubbs, M.T, Balbach, J.
Deposit date:2010-02-18
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
J.Mol.Biol., 398, 2010
7NYQ
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BU of 7nyq by Molmil
Crystal structure of the Mei-P26 NHL domain
Descriptor: Meiotic P26, isoform C
Authors:Salerno-Kochan, A, Gaik, M, Medenbach, J, Glatt, S.
Deposit date:2021-03-23
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26.
Life Sci Alliance, 5, 2022
8QRN
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BU of 8qrn by Molmil
mt-SSU in GTPBP8 knock-out cells, state 4
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRM
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BU of 8qrm by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QU1
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BU of 8qu1 by Molmil
mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 1
Descriptor: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-13
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRK
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BU of 8qrk by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (6.69 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QRL
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BU of 8qrl by Molmil
mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2
Descriptor: 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
8QU5
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BU of 8qu5 by Molmil
mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2
Descriptor: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M.
Deposit date:2023-10-13
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
7P2E
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BU of 7p2e by Molmil
Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Singh, V, Rorbach, J, Amunts, A.
Deposit date:2021-07-05
Release date:2022-07-27
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
Elife, 11, 2022
4J7Z
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BU of 4j7z by Molmil
Thermus thermophilus DNAJ J- and G/F-DOMAINS
Descriptor: Chaperone protein DnaJ 2, GLYCEROL
Authors:Barends, T.R.M, Brosi, R.W, Steinmetz, A, Scherer, A, Hartmann, E, Eschenbach, J, Lorenz, T, Seidel, R, Shoeman, R, Zimmermann, S, Bittl, R, Schlichting, I, Reinstein, J.
Deposit date:2013-02-14
Release date:2013-07-31
Last modified:2024-02-28
Method:EPR (1.64 Å), X-RAY DIFFRACTION
Cite:Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
4J80
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BU of 4j80 by Molmil
Thermus thermophilus DnaJ
Descriptor: Chaperone protein DnaJ 2
Authors:Barends, T.R.M, Brosi, R.W, Steinmetz, A, Scherer, A, Hartmann, E, Eschenbach, J, Lorenz, T, Seidel, R, Shoeman, R, Zimmermann, S, Bittl, R, Schlichting, I, Reinstein, J.
Deposit date:2013-02-14
Release date:2013-07-31
Last modified:2013-10-09
Method:EPR (2.9 Å), X-RAY DIFFRACTION
Cite:Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
7PO4
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BU of 7po4 by Molmil
Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP)
Descriptor: 16SrRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PNY
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BU of 7pny by Molmil
Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation b
Descriptor: 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ...
Authors:Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PO3
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BU of 7po3 by Molmil
Human mitochondrial ribosome small subunit
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PNT
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BU of 7pnt by Molmil
Assembly intermediate of mouse mitochondrial ribosome small subunit without mS37 in complex with RbfA and Tfb1m
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PNW
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BU of 7pnw by Molmil
Mouse mitochondrial ribosome small subunit lacking m5U modification
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PNZ
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BU of 7pnz by Molmil
Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation c
Descriptor: 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ...
Authors:Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PNU
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BU of 7pnu by Molmil
Assembly intermediate of mouse mitochondrial ribosome small subunit without mS37 in complex with RbfA inward conformation
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
7PO0
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BU of 7po0 by Molmil
Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and IF3
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A.
Deposit date:2021-09-08
Release date:2022-06-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022

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