5VOE
| DesGla-XaS195A Bound to Aptamer 11F7t | Descriptor: | Aptamer 11F7t (36-MER), CALCIUM ION, Coagulation factor X, ... | Authors: | Gunaratne, R, Kumar, S, Frederiksen, J.W, Stayrook, S, Lohrmann, J.L, Perry, K, Chabata, C.V, Thalji, N.K, Ho, M.D, Arepally, G, Camire, R.M, Krishnaswamy, S.K, Sullenger, B.A. | Deposit date: | 2017-05-02 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nat. Biotechnol., 36, 2018
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5VOF
| DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban | Descriptor: | 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, CALCIUM ION, Coagulation factor X, ... | Authors: | Krishnaswamy, S, Kumar, S. | Deposit date: | 2017-05-02 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nat. Biotechnol., 36, 2018
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4R97
| Crystal structure of the Fab fragment of KKO | Descriptor: | GLYCEROL, ZINC ION, platelet factor 4 antibody KKO heavy chain, ... | Authors: | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | Deposit date: | 2014-09-03 | Release date: | 2015-12-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4R9W
| Crystal structure of platelet factor 4 complexed with fondaparinux | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4 | Authors: | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | Deposit date: | 2014-09-08 | Release date: | 2015-12-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4R9Y
| Crystal structure of KKOFab in complex with platelet factor 4 | Descriptor: | Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain | Authors: | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | Deposit date: | 2014-09-08 | Release date: | 2015-12-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (4.11 Å) | Cite: | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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