Author results

1RMX
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A SHORT LEXITROPSIN THAT RECOGNIZES THE DNA MINOR GROOVE AT 5'-ACTAGT-3': UNDERSTANDING THE ROLE OF ISOPROPYL-THIAZOLE
Descriptor:5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3', N-[3-(DIMETHYLAMINO)PROPYL]-2-({[4-({[4-(FORMYLAMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-5-ISOPROPYL-1,3-THIAZOLE-4-CARBOXAMIDE
Authors:Anthony, N.G., Johnston, B.F., Khalaf, A.I., Mackay, S.P., Parkinson, J.A., Suckling, C.J., Waigh, R.D.
Deposit date:2003-11-28
Release date:2004-08-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole.
J.Am.Chem.Soc., 126, 2004
1RN9
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A SHORT LEXITROPSIN THAT RECOGNIZES THE DNA MINOR GROOVE AT 5'-ACTAGT-3': UNDERSTANDING THE ROLE OF ISOPROPYL-THIAZOLE
Descriptor:5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3'
Authors:Anthony, N.G., Johnston, B.F., Khalaf, A.I., Mackay, S.P., Parkinson, J.A., Suckling, C.J., Waigh, R.D.
Deposit date:2003-12-01
Release date:2004-08-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole.
J.Am.Chem.Soc., 126, 2004
2MNB
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THIAZOTROPSIN B DNA RECOGNITION SEQUENCE D(CGACGCGTCG)2
Descriptor:5'-D(*CP*GP*AP*CP*GP*CP*GP*TP*CP*G)-3'
Authors:Alniss, H.Y., Salvia, M.-V., Sadikov, M., Golovchenko, I., Anthony, N.G., Khalaf, A.I., Mackay, S.P., Suckling, C.J., Parkinson, J.A.
Deposit date:2014-04-02
Release date:2014-09-17
Method:SOLUTION NMR
Cite:Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem, 15, 2014
2MND
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RECOGNITION COMPLEX OF DNA D(CGACGCGTCG)2 WITH THIAZOTROPSIN B
Descriptor:5'-D(*CP*GP*AP*CP*GP*CP*GP*TP*CP*G)-3', thiazotropsin B
Authors:Alniss, H.Y., Salvia, M.-V., Sadikov, M., Golovchenko, I., Anthony, N.G., Khalaf, A.I., Mackay, S.P., Suckling, C.J., Parkinson, J.A.
Deposit date:2014-04-03
Release date:2014-07-30
Last modified:2014-09-17
Method:SOLUTION NMR
Cite:Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem, 15, 2014
2MNE
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RECOGNITION COMPLEX OF DNA D(CGACTAGTCG)2 WITH THIAZOTROPSIN ANALOGUE AIK-18/51
Descriptor:5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3', AIK-18/51
Authors:Alniss, H.Y., Salvia, M.-V., Sadikov, M., Golovchenko, I., Anthony, N.G., Khalaf, A.I., Mackay, S.P., Suckling, C.J., Parkinson, J.A.
Deposit date:2014-04-03
Release date:2014-07-30
Last modified:2014-09-17
Method:SOLUTION NMR
Cite:Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem, 15, 2014
2MNF
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AIK-18/51 DNA RECOGNITION SEQUENCE D(CGACTAGTCG)2
Descriptor:5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3'
Authors:Alniss, H.Y., Salvia, M.-V., Sadikov, M., Golovchenko, I., Anthony, N.G., Khalaf, A.I., Mackay, S.P., Suckling, C.J., Parkinson, J.A.
Deposit date:2014-04-03
Release date:2014-07-30
Last modified:2014-09-17
Method:SOLUTION NMR
Cite:Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem, 15, 2014
4BXN
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EG5(WT) COMPLEX
Descriptor:KINESIN-LIKE PROTEIN KIF11, ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, ...
Authors:Talapatra, S.K., Anthony, N.G., Mackay, S.P., Kozielski, F.
Deposit date:2013-07-15
Release date:2013-07-31
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2.793 Å)
Cite:The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013
4V3K
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RNF38-UBCH5B-UB COMPLEX
Descriptor:UBIQUITIN-CONJUGATING ENZYME E2 D2, POLYUBIQUITIN-C, E3 UBIQUITIN-PROTEIN LIGASE RNF38, ...
Authors:Buetow, L., Gabrielsen, M., Anthony, N.G., Dou, H., Patel, A., Aitkenhead, H., Sibbet, G.J., Smith, B.O., Huang, D.T.
Deposit date:2014-10-20
Release date:2015-04-08
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin.
Mol.Cell, 58, 2015
4V3L
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RNF38-UB-UBCH5B-UB COMPLEX
Descriptor:UBIQUITIN-CONJUGATING ENZYME E2 D2, POLYUBIQUITIN-C, E3 UBIQUITIN-PROTEIN LIGASE RNF38, ...
Authors:Buetow, L., Gabrielsen, M., Anthony, N.G., Dou, H., Patel, A., Aitkenhead, H., Sibbet, G.J., Smith, B.O., Huang, D.T.
Deposit date:2014-10-20
Release date:2015-04-08
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin.
Mol.Cell, 58, 2015
4A1Z
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EG5-1
Descriptor:KINESIN-LIKE PROTEIN KIF11, MAGNESIUM ION, NITRATE ION, ...
Authors:Talapatra, S.K., Kozielski, F.
Deposit date:2011-09-20
Release date:2012-10-31
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013
4A28
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EG5-2
Descriptor:KINESIN-LIKE PROTEIN KIF11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Talapatra, S.K., Kozielski, F.
Deposit date:2011-09-22
Release date:2012-10-31
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013
4AS7
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EG5 COMPLEX 1
Descriptor:KINESIN-LIKE PROTEIN KIF11, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Talapatra, S.K., Kozielski, F.
Deposit date:2012-04-29
Release date:2013-05-15
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013
4B7B
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EG5-3
Descriptor:KINESIN-LIKE PROTEIN KIF11, ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, ...
Authors:Talapatra, S.K., Kozielski, F.
Deposit date:2012-08-17
Release date:2013-07-31
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013