Author results

1LKN
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SOLUTION NMR STRUCTURE OF PROTEIN TM_1112 FROM THERMOTOGA MARITIMA. ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS TARGET TM1112_1_89; NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET VT74.
Descriptor:hypothetical protein tm1112
Authors:Xia, Y., Yee, A., Semesi, A., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-04-25
Release date:2003-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Hypothetical Protein tm1112
to be published
4N1Z
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CRYSTAL STRUCTURE OF HUMAN FARNESYL DIPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-1222
Descriptor:Farnesyl pyrophosphate synthase, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Liu, Y.L., Xia, Y., Zhang, Y., Verma, I., Oldfield, E.
Deposit date:2013-10-04
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
Sci Transl Med, 6, 2014
5GNV
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STRUCTURE OF PSD-95/MAP1A COMPLEX REVEALS UNIQUE TARGET RECOGNITION MODE OF MAGUK GK DOMAIN
Descriptor:Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION
Authors:Shang, Y., Xia, Y., Zhu, R., Zhu, J.
Deposit date:2016-07-25
Release date:2017-08-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
4LQT
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1.10A RESOLUTION CRYSTAL STRUCTURE OF A SUPERFOLDER GREEN FLUORESCENT PROTEIN (W57A) MUTANT
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL
Authors:Lovell, S., Xia, Y., Vo, B., Battaile, K.P., Egan, C., Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
4LQU
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1.60A RESOLUTION CRYSTAL STRUCTURE OF A SUPERFOLDER GREEN FLUORESCENT PROTEIN (W57G) MUTANT
Descriptor:Green fluorescent protein
Authors:Lovell, S., Xia, Y., Vo, B., Battaile, K.P., Egan, C., Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
5SXY
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THE SOLUTION NMR STRUCTURE FOR THE PQQD TRUNCATION OF METHYLOBACTERIUM EXTORQUENS PQQCD REPRESENTING A FUNCTIONAL AND STAND-ALONE RIBOSOMALLY SYNTHESIZED AND POST-TRANSLATIONAL MODIFIED (RIPP) RECOGNITION ELEMENT (RRE)
Descriptor:Bifunctional coenzyme PQQ synthesis protein C/D
Authors:Evans, R.L., Xia, Y., Wilmot, C.M.
Deposit date:2016-08-10
Release date:2017-05-24
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone.
Biochemistry, 56, 2017
1IAX
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CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH PLP
Descriptor:1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Huai, Q., Xia, Y., Chen, Y., Callahan, B., Li, N., Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001
1IAY
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CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH COFACTOR PLP AND INHIBITOR AVG
Descriptor:1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, PYRIDOXAL-5'-PHOSPHATE, 2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID
Authors:Huai, Q., Xia, Y., Chen, Y., Callahan, B., Li, N., Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001
3WP0
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CRYSTAL STRUCTURE OF DLG GK IN COMPLEX WITH A PHOSPHOR-LGL2 PEPTIDE
Descriptor:Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, GLYCEROL
Authors:Zhu, J., Shang, Y., Wan, Q., Xia, Y., Chen, J., Du, Q., Zhang, M.
Deposit date:2014-01-08
Release date:2014-03-19
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (2.039 Å)
Cite:Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
3WP1
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PHOSPHORYLATION-DEPENDENT INTERACTION BETWEEN TUMOR SUPPRESSORS DLG AND LGL
Descriptor:Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION
Authors:Zhu, J., Shang, Y., Wan, Q., Xia, Y., Chen, J., Du, Q., Zhang, M.
Deposit date:2014-01-08
Release date:2014-03-19
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
5KSI
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CRYSTAL STRUCTURE OF DEOXYGENATED HEMOGLOBIN IN COMPLEX WITH SPHINGOSINE PHOSPHATE AND 2,3-BISPHOSPHOGLYCERATE
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ahmed, M.H., Safo, M.K., Xia, Y.
Deposit date:2016-07-08
Release date:2017-07-26
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
5KSJ
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CRYSTAL STRUCTURE OF DEOXYGENATED HEMOGLOBIN IN COMPLEX WITH SPHINGOSINE PHOSPHATE
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ahmed, M.H., Safo, M.K., Xia, Y.
Deposit date:2016-07-08
Release date:2017-07-26
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
2N9B
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SOLUTION NMR STRUCTURE OF ANTIPARALLEL MYOSIN-10:GCN4 TANDEM COILED-COIL
Descriptor:Unconventional myosin-X, General control protein GCN4 fusion
Authors:Vavra, K.C., Xia, Y., Rock, R.S.
Deposit date:2015-11-12
Release date:2016-06-15
Last modified:2018-10-10
Method:SOLUTION NMR
Cite:Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection
Biophys.J., 110, 2016
2HEM
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NMR STRUCTURE AND MG2+ BINDING OF AN RNA SEGMENT THAT UNDERLIES THE L7/L12 STALK IN THE E.COLI 50S RIBOSOMAL SUBUNIT.
Descriptor:5'-R(P*GP*GP*GP*AP*AP*GP*GP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*CP*GP*GP*CP*CP*C)-3'
Authors:Zhao, Q., Nagaswamy, U., Lee, H., Xia, Y., Gao, X., Fox, G.
Deposit date:2006-06-21
Release date:2006-09-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit
Nucleic Acids Res., 33, 2005
2MZ0
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SOLUTION NMR STRUCTURE OF PDFL2.1 FROM ARABIDOPSIS THALIANA
Descriptor:Defensin-like protein 32
Authors:Omidvar, R., Bohlmann, H., Xia, Y., Veglia, G.
Deposit date:2015-02-05
Release date:2016-02-17
Method:SOLUTION NMR
Cite:Solution NMR Structure of PDFL2.1 from Arabidopsis thaliana
To be Published
4A4R
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UNAC TETRALOOPS: TO WHAT EXTENT CAN THEY MIMIC GNRA TETRALOOPS
Descriptor:5'-R(*GMP*GP*AP*CP*CP*CP*GP*GP*CP*UP*AP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q., Huang, H., Nagaswamy, U., Xia, Y., Gao, X., Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4S
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UNAC TETRALOOPS: TO WHAT EXTENT CAN THEY MIMIC GNRA TETRALOOPS
Descriptor:5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*CP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q., Huang, H., Nagaswamy, U., Xia, Y., Gao, X., Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4T
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UNAC TETRALOOPS: TO WHAT EXTENT CAN THEY MIMIC GNRA TETRALOOPS
Descriptor:5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*UP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q., Huang, H., Nagaswamy, U., Xia, Y., Gao, X., Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4U
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UNAC TETRALOOPS: TO WHAT EXTENT CAN THEY MIMIC GNRA TETRALOOPS
Descriptor:5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*GP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q., Huang, H., Nagaswamy, U., Xia, Y., Gao, X., Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4I0U
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IMPROVED STRUCTURE OF THERMOTOGA MARITIMA CORA AT 2.7 A RESOLUTION
Descriptor:Magnesium transport protein CorA, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Nordin, N., Guskov, A., Phua, T., Sahaf, N., Xia, Y., Lu, S.Y., Eshaghi, H., Eshaghi, S.
Deposit date:2012-11-19
Release date:2013-03-06
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport.
Biochem.J., 451, 2013
4OR2
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HUMAN CLASS C G PROTEIN-COUPLED METABOTROPIC GLUTAMATE RECEPTOR 1 IN COMPLEX WITH A NEGATIVE ALLOSTERIC MODULATOR
Descriptor:Soluble cytochrome b562, Metabotropic glutamate receptor 1, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, ...
Authors:Wu, H., Wang, C., Gregory, K.J., Han, G.W., Cho, H.P., Xia, Y., Niswender, C.M., Katritch, V., Cherezov, V., Conn, P.J., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2014-02-10
Release date:2014-03-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
5YGI
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CRYSTAL STRUCTURE OF HUMAN FPPS IN COMPLEX WITH AN INHIBITOR THZ93
Descriptor:Farnesyl pyrophosphate synthase, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Li, X.
Deposit date:2017-09-23
Release date:2018-09-26
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.177 Å)
Cite:The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
5VRL
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CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333.
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], (~{N}~{E})-~{N}-[[2-[[2-ethylsulfonyl-1,1-bis(oxidanyl)-3,4-dihydro-2,3,1$l^{4}-benzodiazaborinin-7-yl]oxy]-5-(trifluoromethyl)phenyl]methylidene]hydroxylamine
Authors:Abendroth, J., Edwards, T.E., Lorimer, D.
Deposit date:2017-05-11
Release date:2018-05-16
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA.
Life Sci Alliance, 1, 2018
5VRM
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CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333.
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3-oxidanyl-4-[[1-oxidanyl-6-[4-(trifluoromethyl)phenoxy]-3~{H}-2,1$l^{4}-benzoxaborol-1-yl]oxy]oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
Authors:Abendroth, J., Edwards, T.E., Lorimer, D.
Deposit date:2017-05-11
Release date:2018-05-16
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA.
Life Sci Alliance, 1, 2018
5VRN
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CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333.
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-4-[[5-[4-cyano-2-[(~{E})-hydroxyiminomethyl]phenoxy]-1-oxidanyl-3~{H}-2,1$l^{4}-benzoxaborol-1-yl]oxy]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
Authors:Abendroth, J., Edwards, T.E., Lorimer, D.
Deposit date:2017-05-11
Release date:2018-05-16
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA.
Life Sci Alliance, 1, 2018
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