Author results

1E50
  • Download 1e50
  • View 1e50
Molmil generated image of 1e50
AML1/CBFBETA COMPLEX
Descriptor:CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA
Authors:Warren, A.J., Bravo, J., Williams, R.L., Rabbits, T.H.
Deposit date:2000-07-13
Release date:2001-07-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta
Embo J., 19, 2000
4ZXR
  • Download 4zxr
  • View 4zxr
Molmil generated image of 4zxr
STRUCTURE OF THAUMATIN WRAPPED IN GRAPHENE WITHIN VACUUM
Descriptor:Thaumatin-1, L(+)-TARTARIC ACID, GLYCEROL
Authors:Aller, P., Warren, A.J., Trincao, J., Evans, G.
Deposit date:2015-05-20
Release date:2015-10-14
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:In vacuo X-ray data collection from graphene-wrapped protein crystals.
Acta Crystallogr.,Sect.D, 71, 2015
2L9N
  • Download 2l9n
  • View 2l9n
Molmil generated image of 2l9n
STRUCTURE OF THE HUMAN SHWACHMAN-BODIAN-DIAMOND SYNDROME (SBDS) PROTEIN
Descriptor:Ribosome maturation protein SBDS
Authors:Hilcenko, C., Freund, S.M.V., Warren, A.J.
Deposit date:2011-02-21
Release date:2011-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.
Genes Dev., 25, 2011
4H7W
  • Download 4h7w
  • View 4h7w
Molmil generated image of 4h7w
CRYSTAL STRUCTURE OF HUMAN C16ORF57
Descriptor:UPF0406 protein C16orf57, GLYCEROL, CHLORIDE ION
Authors:Hilcenko, C., Simpson, P.J., Warren, A.J.
Deposit date:2012-09-21
Release date:2013-02-06
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia.
Blood, 121, 2013
1H9D
  • Download 1h9d
  • View 1h9d
Molmil generated image of 1h9d
AML1/CBF-BETA/DNA COMPLEX
Descriptor:CORE-BINDING FACTOR ALPHA SUBUNIT1, CORE-BINDING FACTOR CBF-BETA, DNA (5'-(*GP*TP*TP*GP*CP*GP*GP*TP*TP*G)-3'), ...
Authors:Bravo, J., Warren, A.J.
Deposit date:2001-03-07
Release date:2001-03-31
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Leukemia-Associated Aml1 (Runx1)-Cbfbeta Complex Functions as a DNA-Induced Molecular Clamp
Nat.Struct.Biol., 8, 2001
1T95
  • Download 1t95
  • View 1t95
Molmil generated image of 1t95
CRYSTAL STRUCTURE OF THE SHWACHMAN-BODIAN-DIAMOND SYNDROME PROTEIN ORTHOLOGUE FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Hypothetical protein AF0491
Authors:Shammas, C., Warren, A.J.
Deposit date:2004-05-14
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome.
J.Biol.Chem., 280, 2005
2J2S
  • Download 2j2s
  • View 2j2s
Molmil generated image of 2j2s
SOLUTION STRUCTURE OF THE NONMETHYL-CPG-BINDING CXXC DOMAIN OF THE LEUKAEMIA-ASSOCIATED MLL HISTONE METHYLTRANSFERASE
Descriptor:ZINC FINGER PROTEIN HRX, ZINC ION
Authors:Allen, M.D., Grummitt, C.G., Hilcenko, C., Young-Min, S., Tonkin, L.M., Johnson, C.M., Bycroft, M., Warren, A.J.
Deposit date:2006-08-17
Release date:2006-08-21
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Solution Structure of the Nonmethyl-Cpg-Binding Cxxc Domain of the Leukaemia-Associated Mll Histone Methyltransferase
Embo J., 25, 2006
3QRL
  • Download 3qrl
  • View 3qrl
Molmil generated image of 3qrl
CRYSTAL STRUCTURE OF THE TAF14 YEATS DOMAIN
Descriptor:Transcription initiation factor TFIID subunit 14, TRIETHYLENE GLYCOL
Authors:Simpson, P.J., Warren, A.J.
Deposit date:2011-02-18
Release date:2012-02-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Taf14 YEATS domain
To be Published
5AN9
  • Download 5an9
  • View 5an9
Molmil generated image of 5an9
MECHANISM OF EIF6 RELEASE FROM THE NASCENT 60S RIBOSOMAL SUBUNIT
Descriptor:60S RIBOSOMAL PROTEIN L3, 60S RIBOSOMAL PROTEIN L9, 60S ACIDIC RIBOSOMAL PROTEIN P0, ...
Authors:Weis, F., Giudice, E., Churcher, M., Jin, L., Hilcenko, C., Wong, C.C., Traynor, D., Kay, R.R., Warren, A.J.
Deposit date:2015-09-06
Release date:2015-10-21
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 22, 2015
5ANB
  • Download 5anb
  • View 5anb
Molmil generated image of 5anb
MECHANISM OF EIF6 RELEASE FROM THE NASCENT 60S RIBOSOMAL SUBUNIT
Descriptor:60S RIBOSOMAL PROTEIN L3, 60S RIBOSOMAL PROTEIN L9, 60S ACIDIC RIBOSOMAL PROTEIN P0, ...
Authors:Weis, F., Giudice, E., Churcher, M., Jin, L., Hilcenko, C., Wong, C.C., Traynor, D., Kay, R.R., Warren, A.J.
Deposit date:2015-09-06
Release date:2015-10-21
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 22, 2015
5ANC
  • Download 5anc
  • View 5anc
Molmil generated image of 5anc
MECHANISM OF EIF6 RELEASE FROM THE NASCENT 60S RIBOSOMAL SUBUNIT
Descriptor:60S RIBOSOMAL PROTEIN L3, 60S RIBOSOMAL PROTEIN L9, 60S ACIDIC RIBOSOMAL PROTEIN P0, ...
Authors:Weis, F., Giudice, E., Churcher, M., Jin, L., Hilcenko, C., Wong, C.C., Traynor, D., Kay, R.R., Warren, A.J.
Deposit date:2015-09-06
Release date:2015-10-21
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 22, 2015
6EZO
  • Download 6ezo
  • View 6ezo
Molmil generated image of 6ezo
EUKARYOTIC INITIATION FACTOR EIF2B IN COMPLEX WITH ISRIB
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Faille, A., Weis, F., Zyryanova, A., Warren, A.J., Ron, D.
Deposit date:2017-11-16
Release date:2018-03-28
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Science, 359, 2018
6QIK
  • Download 6qik
  • View 6qik
Molmil generated image of 6qik
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S ribosomal RNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-01-20
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6QKL
  • Download 6qkl
  • View 6qkl
Molmil generated image of 6qkl
MECHANISM OF EIF6 RELEASE FROM THE NASCENT 60S RIBOSOMAL SUBUNIT
Descriptor:26S RIBOSOMAL RNA, 60S ribosomal protein L3, 60S ribosomal protein L9, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-01-29
Release date:2019-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of eIF6 release from the nascent 60S ribosomal subunit.
Nat.Struct.Mol.Biol., 22, 2015
6QT0
  • Download 6qt0
  • View 6qt0
Molmil generated image of 6qt0
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S rRNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-02-22
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6QTZ
  • Download 6qtz
  • View 6qtz
Molmil generated image of 6qtz
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S rRNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-02-26
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6RI5
  • Download 6ri5
  • View 6ri5
Molmil generated image of 6ri5
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S RNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-04-23
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6RZZ
  • Download 6rzz
  • View 6rzz
Molmil generated image of 6rzz
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S ribosomal RNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6S05
  • Download 6s05
  • View 6s05
Molmil generated image of 6s05
CRYO-EM STRUCTURES OF LSG1-TAP PRE-60S RIBOSOMAL PARTICLES
Descriptor:25S ribosomal RNA, 60S ribosomal protein L2-A, 60S ribosomal protein L3, ...
Authors:Kargas, V., Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
2VXD
  • Download 2vxd
  • View 2vxd
Molmil generated image of 2vxd
THE STRUCTURE OF THE C-TERMINAL DOMAIN OF NUCLEOPHOSMIN
Descriptor:NUCLEOPHOSMIN
Authors:Bycroft, M., Grummitt, C.G.
Deposit date:2008-07-03
Release date:2008-07-15
Last modified:2013-07-24
Method:SOLUTION NMR
Cite:Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia.
J.Biol.Chem., 283, 2008