Author results

1I9B
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X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)
Descriptor:ACETYLCHOLINE BINDING PROTEIN, CALCIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Brejc, K., van Dijk, W.J., Klaassen, R., Schuurmans, M., van der Oost, J., Smit, A.B., Sixma, T.K.
Deposit date:2001-03-18
Release date:2001-05-16
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.
Nature, 411, 2001
2HTN
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E. COLI BACTERIOFERRITIN IN ITS AS-ISOLATED FORM
Descriptor:Bacterioferritin, FE (III) ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:van Eerde, A., Wolterink-Van Loo, S., Van Der Oost, J., Dijkstra, B.W.
Deposit date:2006-07-26
Release date:2006-11-21
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fortuitous structure determination of 'as-isolated' Escherichia coli bacterioferritin in a novel crystal form.
Acta Crystallogr.,Sect.F, 62, 2006
3JUR
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THE CRYSTAL STRUCTURE OF A HYPERTHERMOACTIVE EXOPOLYGALACTURONASE FROM THERMOTOGA MARITIMA
Descriptor:Exo-poly-alpha-D-galacturonosidase
Authors:Pijning, T., van Pouderoyen, G., Kluskens, L.D., van der Oost, J., Dijkstra, B.W.
Deposit date:2009-09-15
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer
Febs Lett., 2009
3DOH
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CRYSTAL STRUCTURE OF A THERMOSTABLE ESTERASE
Descriptor:esterase, SULFATE ION
Authors:Levisson, M., Sun, L., Hendriks, S., Dijkstra, B.W., Van der Oost, J., Kengen, S.W.M.
Deposit date:2008-07-04
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
3DOI
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CRYSTAL STRUCTURE OF A THERMOSTABLE ESTERASE COMPLEX WITH PARAOXON
Descriptor:esterase, DIETHYL PHOSPHONATE
Authors:Levisson, M., Sun, L., Hendriks, S., Dijkstra, B.W., Van der Oost, J., Kengen, S.W.M.
Deposit date:2008-07-04
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
1I1G
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CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS
Descriptor:TRANSCRIPTIONAL REGULATOR LRPA
Authors:Leonard, P.M., Smits, S.H.J., Sedelnikova, S.E., Brinkman, A.B., de Vos, W.M., van der Oost, J., Rice, D.W., Rafferty, J.B.
Deposit date:2001-02-01
Release date:2002-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus.
EMBO J., 20, 2001
1X7N
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THE CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS PHOSPHOGLUCOSE ISOMERASE WITH BOUND 5-PHOSPHO-D-ARABINONATE AND MANGANESE
Descriptor:Glucose-6-phosphate isomerase, MANGANESE (II) ION, 5-PHOSPHOARABINONIC ACID
Authors:Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
Deposit date:2004-08-16
Release date:2004-10-12
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X82
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CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE FROM PYROCOCCUS FURIOSUS WITH BOUND 5-PHOSPHO-D-ARABINONATE
Descriptor:Glucose-6-phosphate isomerase, 5-PHOSPHOARABINONIC ACID
Authors:Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
Deposit date:2004-08-17
Release date:2004-10-12
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X8E
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CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS PHOSPHOGLUCOSE ISOMERASE FREE ENZYME
Descriptor:Glucose-6-phosphate isomerase
Authors:Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
Deposit date:2004-08-18
Release date:2004-10-12
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1XRK
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CRYSTAL STRUCTURE OF A MUTANT BLEOMYCIN BINDING PROTEIN FROM STREPTOALLOTEICHUS HINDUSTANUS DISPLAYING INCREASED THERMOSTABILITY
Descriptor:Bleomycin resistance protein, SULFATE ION, BLEOMYCIN A2
Authors:Brouns, S.J.J., Wu, H., Akerboom, J., Turnbull, A.P., de Vos, W.M., Van der Oost, J.
Deposit date:2004-10-15
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineering a selectable marker for hyperthermophiles
J.Biol.Chem., 280, 2005
2CG4
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STRUCTURE OF E.COLI ASNC
Descriptor:REGULATORY PROTEIN ASNC, ASPARAGINE, MAGNESIUM ION
Authors:Thaw, P., Sedelnikova, S.E., Muranova, T., Wiese, S., Ayora, S., Alonso, J.C., Brinkman, A.B., Akerboom, J., van der Oost, J., Rafferty, J.B.
Deposit date:2006-02-27
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family.
Nucleic Acids Res., 34, 2006
2H6E
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CRYSTAL STRUCTURE OF THE D-ARABINOSE DEHYDROGENASE FROM SULFOLOBUS SOLFATARICUS
Descriptor:D-arabinose 1-dehydrogenase, ZINC ION
Authors:Brouns, S.J.J., Turnbull, A.P., Akerboom, J., Willemen, H.L.D.M., De Vos, W.M., Van der Oost, J.
Deposit date:2006-05-31
Release date:2007-06-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus
J.Mol.Biol., 371, 2007
2QTF
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CRYSTAL STRUCTURE OF A GTP-BINDING PROTEIN FROM THE HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS SOLFATARICUS
Descriptor:GTP-binding protein, CADMIUM ION, SULFATE ION, ...
Authors:Wu, H., Sun, L., Brouns, S.J., Fu, S., Rao, Z., Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2QTH
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CRYSTAL STRUCTURE OF A GTP-BINDING PROTEIN FROM THE HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS SOLFATARICUS IN COMPLEX WITH GDP
Descriptor:GTP-binding protein, CADMIUM ION, MAGNESIUM ION, ...
Authors:Wu, H., Sun, L., Brouns, S.J., Fu, S., Rao, Z., Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
4Q2C
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CRYSTAL STRUCTURE OF CRISPR-ASSOCIATED PROTEIN
Descriptor:CRISPR-associated helicase Cas3, NICKEL (II) ION
Authors:Gong, B., Shin, M., Sun, J., van der Oost, J., Kim, J.-S.
Deposit date:2014-04-07
Release date:2014-11-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
Proc.Natl.Acad.Sci.USA, 2014
4Q2D
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CRYSTAL STRUCTURE OF CRISPR-ASSOCIATED PROTEIN IN COMPLEX WITH 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
Descriptor:CRISPR-associated helicase Cas3, NICKEL (II) ION, MAGNESIUM ION, ...
Authors:Gong, B., Shin, M., Sun, J., van der Oost, J., Kim, J.-S.
Deposit date:2014-04-07
Release date:2014-11-19
Method:X-RAY DIFFRACTION (2.771 Å)
Cite:Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
Proc.Natl.Acad.Sci.USA, 2014
6QZK
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STRUCTURE OF CLOSTRIDIUM BUTYRICUM ARGONAUTE BOUND TO A GUIDE DNA (5' DEOXYCYTIDINE) AND A 19-MER TARGET DNA
Descriptor:Clostridium butyricum Argonaute, siDNA guide (5'-D(P*CP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), ...
Authors:Swarts, D.C., Jinek, M., Hegge, J.W., Van der Oost, J.
Deposit date:2019-03-11
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.548 Å)
Cite:DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.
Nucleic Acids Res., 2019
1B3B
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THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K
Descriptor:PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S., Lebbink, J.H.G., Van Der Oost, J., Devos, W.M., Rice, D., Ladenstein, R.
Deposit date:1998-12-07
Release date:1999-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
1R6V
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CRYSTAL STRUCTURE OF FERVIDOLYSIN FROM FERVIDOBACTERIUM PENNIVORANS, A KERATINOLYTIC ENZYME RELATED TO SUBTILISIN
Descriptor:subtilisin-like serine protease, CALCIUM ION
Authors:Kim, J.S., Kluskens, L.D., de Vos, W.M., Huber, R., van der Oost, J.
Deposit date:2003-10-17
Release date:2004-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin.
J.Mol.Biol., 335, 2004
1S4E
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PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM
Descriptor:Galactokinase, ALPHA D-GALACTOSE, MAGNESIUM ION, ...
Authors:Hartley, A., Glynn, S.E., Barynin, V., Baker, P.J., Sedelnikova, S.E., Verhees, C., de Geus, D., van der Oost, J., Timson, D.J., Reece, R.J., Rice, D.W.
Deposit date:2004-01-16
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
2TMG
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THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E
Descriptor:PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S., Lebbink, J.H.G., van der Oost, J., de Vos, W.M., Rice, D., Ladenstein, R.
Deposit date:1998-12-04
Release date:1999-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
5FRD
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STRUCTURE OF A THERMOPHILIC ESTERASE
Descriptor:CARBOXYLESTERASE (EST-2), COENZYME A, CHLORIDE ION, ...
Authors:Sayer, C., Finnigan, W., Isupov, M.N., Levisson, M., Kengen, S.W.M., van der Oost, J., Harmer, N., Littlechild, J.A.
Deposit date:2015-12-17
Release date:2016-05-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site.
Sci.Rep., 6, 2016
5NFV
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CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE FNCAS12 MUTANT BOUND TO AN R-LOOP STRUCTURE CONTAINING A PRE-CRRNA MIMIC AND FULL-LENGTH DNA TARGET
Descriptor:CRISPR-associated endonuclease Cpf1, pre-crRNA, DNA target strand, ...
Authors:Swarts, D.C., van der Oost, J., Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
5NG6
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CRYSTAL STRUCTURE OF FNCAS12A BOUND TO A CRRNA
Descriptor:CRISPR-associated endonuclease Cpf1, crRNA, MAGNESIUM ION
Authors:Swarts, D.C., van der Oost, J., Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Method:X-RAY DIFFRACTION (3.342 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
2MEZ
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FLEXIBLE ANCHORING OF ARCHAEAL MBF1 ON RIBOSOMES SUGGESTS ROLE AS RECRUITMENT FACTOR
Descriptor:Multiprotein Bridging Factor (MBP-like)
Authors:Launay, H., Blombarch, F., Camilloni, C., Vendruscolo, M., van des Oost, J., Christodoulou, J.
Deposit date:2013-10-03
Release date:2014-06-25
Last modified:2014-08-20
Method:SOLUTION NMR
Cite:Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Biochem.J., 462, 2014
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