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4XQ8
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BU of 4xq8 by Molmil
Human DNA polymerase lambda- MgdATP binary complex and complex with 6 paired DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Tsai, M.D, Liu, M.S.
Deposit date:2015-01-19
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
4XRH
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BU of 4xrh by Molmil
Human DNA polymerase lambda- MgdTTP binary and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-01-21
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
6ISI
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BU of 6isi by Molmil
Structure of 9N-I DNA polymerase incorporation with 3'-CL in the active site
Descriptor: 3-[2-[2-(2-azanylethoxy)ethoxy]ethoxy]propanoic acid, CALCIUM ION, DNA (5'-D(P*AP*CP*GP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISG
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BU of 6isg by Molmil
Structure of 9N-I DNA polymerase incorporation with dG in the active site
Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*CP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*G)-3'), ...
Authors:Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISF
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BU of 6isf by Molmil
Structure of 9N-I DNA polymerase incorporation with dT in the active site
Descriptor: CALCIUM ION, DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*T)-3'), ...
Authors:Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISH
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BU of 6ish by Molmil
Structure of 9N-I DNA polymerase incorporation with 3'-AL in the active site
Descriptor: CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*(DAL))-3'), ...
Authors:Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6IS7
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BU of 6is7 by Molmil
Structure of 9N-I DNA polymerase incorporation with dA in the active site
Descriptor: CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*A)-3'), ...
Authors:Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H.
Deposit date:2018-11-15
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6IPJ
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BU of 6ipj by Molmil
Binary Complex of Human DNA Polymerase Mu with MndTTP
Descriptor: DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPG
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BU of 6ipg by Molmil
Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mg-8oxodGMP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPN
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BU of 6ipn by Molmil
Binary Complex of Human DNA Polymerase Mu with MgdGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPH
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BU of 6iph by Molmil
Binary Complex of Human DNA Polymerase Mu with MndATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPE
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BU of 6ipe by Molmil
Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mg-8oxodGMP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPK
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BU of 6ipk by Molmil
Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
7CGY
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BU of 7cgy by Molmil
Human DMC1 Q244M mutant of the post-synaptic complexes
Descriptor: CALCIUM ION, Meiotic recombination protein DMC1/LIM15 homolog, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y.
Deposit date:2020-07-03
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
7C9C
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BU of 7c9c by Molmil
Human DMC1 pre-synaptic complexes
Descriptor: CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Meiotic recombination protein DMC1/LIM15 homolog, ...
Authors:Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D.
Deposit date:2020-06-05
Release date:2020-11-25
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
7C99
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BU of 7c99 by Molmil
Human DMC1 post-synaptic complexes with mismatched dsDNA
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D.
Deposit date:2020-06-05
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
7C9A
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BU of 7c9a by Molmil
Human RAD51 post-synaptic complexes mutant (V273P, D274G)
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y.
Deposit date:2020-06-05
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
7C98
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BU of 7c98 by Molmil
Human DMC1 post-synaptic complexes
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D.
Deposit date:2020-06-05
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
5CHG
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BU of 5chg by Molmil
Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-10
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CP2
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BU of 5cp2 by Molmil
Human DNA polymerase lambda L431A mutant- Apoenzyme and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-21
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CJ7
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BU of 5cj7 by Molmil
Human DNA polymerase lambda L431A mutant- MgdTTP binary and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-14
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CWR
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BU of 5cwr by Molmil
Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-28
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DDY
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BU of 5ddy by Molmil
Binary complex of human Polymerase lambda with dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, MAGNESIUM ION, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-08-25
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DKW
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BU of 5dkw by Molmil
Ternary crystal structure of polymerase lambda with a GA mispair at the primer terminus with Ca2+ in the active
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-09-04
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DDM
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BU of 5ddm by Molmil
Human DNA polymerase lambda- Apoenzyme and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-08-25
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016

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