4XQ8

Human DNA polymerase lambda- MgdATP binary complex and complex with 6 paired DNA

Summary for 4XQ8

• Entry DOI: 10.2210/pdb4xq8/pdb
• Descriptor: DNA polymerase lambda, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ... (6 entities in total)
• Functional Keywords: complex, mgdatp, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q9UGP5
• Total number of polymer chains: 4
• Total formula weight: 78830.05

Authors

Tsai, M.D.,Liu, M.S. (deposition date: 2015-01-19, release date: 2016-02-24, Last modification date: 2023-11-08)

• Primary citation: Liu, M.S.,Tsai, H.Y.,Liu, X.X.,Ho, M.C.,Wu, W.J.,Tsai, M.D.; Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda; J.Am.Chem.Soc., 138:2389-2398, 2016; PubMed: 26836966; DOI: 10.1021/jacs.5b13368

Experimental method

X-RAY DIFFRACTION (2.798 Å)