4Y1P
| Crystal structure of 3-isopropylmalate dehydrogenase (Saci_0600) from Sulfolobus acidocaldarius complex with 3-isopropylmalate and Mg2+ | Descriptor: | 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, MAGNESIUM ION, ... | Authors: | Takahashi, K, Tomita, T, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2015-02-08 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of two beta-decarboxylating dehydrogenases from Sulfolobus acidocaldarius Extremophiles, 20, 2016
|
|
4YB4
| Crystal structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate, magnesium ion (II) and NADH | Descriptor: | (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Takahashi, K, Tomita, T, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2015-02-18 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate, magnesium(II) and NADH To Be Published
|
|
3AI7
| Crystal Structure of Bifidobacterium Longum Phosphoketolase | Descriptor: | CALCIUM ION, THIAMINE DIPHOSPHATE, Xylulose-5-phosphate/fructose-6-phosphate phosphoketolase | Authors: | Takahashi, K, Tagami, U, Shimba, N, Kashiwagi, T, Ishikawa, K, Suzuki, E. | Deposit date: | 2010-05-10 | Release date: | 2010-09-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium Febs Lett., 584, 2010
|
|
3H1V
| Human glucokinase in complex with a synthetic activator | Descriptor: | 1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dione, Glucokinase, SODIUM ION, ... | Authors: | Kamata, K, Takahashi, K. | Deposit date: | 2009-04-14 | Release date: | 2009-10-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators. Bioorg.Med.Chem., 17, 2009
|
|
7VUC
| |
1A0F
| CRYSTAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE FROM ESCHERICHIA COLI COMPLEXED WITH GLUTATHIONESULFONIC ACID | Descriptor: | GLUTATHIONE S-TRANSFERASE, GLUTATHIONE SULFONIC ACID | Authors: | Nishida, M, Harada, S, Noguchi, S, Inoue, H, Takahashi, K, Satow, Y. | Deposit date: | 1997-11-29 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106. J.Mol.Biol., 281, 1998
|
|
1F54
| SOLUTION STRUCTURE OF THE APO N-TERMINAL DOMAIN OF YEAST CALMODULIN | Descriptor: | CALMODULIN | Authors: | Ishida, H, Takahashi, K, Nakashima, K, Kumaki, Y, Nakata, M, Hikichi, K, Yazawa, M. | Deposit date: | 2000-06-13 | Release date: | 2003-07-15 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution Structures of the N-terminal Domain of Yeast Calmodulin:
Ca2+-Dependent Conformational Change and Its Functional Implication Biochemistry, 39, 2000
|
|
1F55
| SOLUTION STRUCTURE OF THE CALCIUM BOUND N-TERMINAL DOMAIN OF YEAST CALMODULIN | Descriptor: | CALCIUM ION, CALMODULIN | Authors: | Ishida, H, Takahashi, K, Nakashima, K, Kumaki, Y, Nakata, M, Hikichi, K, Yazawa, M. | Deposit date: | 2000-06-13 | Release date: | 2003-07-15 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution Structures of the N-terminal Domain of Yeast Calmodulin:
Ca2+-Dependent Conformational Change and Its Functional Implication Biochemistry, 39, 2000
|
|
1DET
| RIBONUCLEASE T1 CARBOXYMETHYLATED AT GLU 58 IN COMPLEX WITH 2'GMP | Descriptor: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1, SODIUM ION | Authors: | Ishikawa, K, Suzuki, E, Tanokura, M, Takahashi, K. | Deposit date: | 1996-02-20 | Release date: | 1996-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of ribonuclease T1 carboxymethylated at Glu58 in complex with 2'-GMP. Biochemistry, 35, 1996
|
|
1IYY
| NMR STRUCTURE OF Gln25-RIBONUCLEASE T1, 24 STRUCTURES | Descriptor: | RIBONUCLEASE T1 | Authors: | Hatano, K, Kojima, M, Suzuki, E, Tanokura, M, Takahashi, K. | Deposit date: | 2002-09-12 | Release date: | 2003-10-07 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Determination of the NMR structure of Gln25-ribonuclease T1. Biol. Chem., 384, 2003
|
|
5D45
| Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid | Descriptor: | 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | Deposit date: | 2015-08-07 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
|
|
5D48
| Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid | Descriptor: | 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy)phenyl]-1H-indol-1-yl}propanoic acid, Fatty acid-binding protein, adipocyte, ... | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | Deposit date: | 2015-08-07 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
|
|
5D4A
| Crystal Structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl)propanoic acid | Descriptor: | 3-(2-phenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | Deposit date: | 2015-08-07 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
|
|
5D47
| Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl] propanoic acid | Descriptor: | 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl]propanoic acid, Fatty acid-binding protein, adipocyte | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | Deposit date: | 2015-08-07 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
|
|
1TFO
| Ribonuclease from Escherichia coli complexed with its inhibitor protein | Descriptor: | Colicin D, Colicin D immunity protein | Authors: | Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. | Deposit date: | 2004-05-27 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Relation between tRNase activity and the structure of colicin D according to X-ray crystallography Biochem.Biophys.Res.Commun., 322, 2004
|
|
1TFK
| Ribonuclease from Escherichia coli complexed with its inhibtor protein | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Colicin D, Colicin D immunity protein | Authors: | Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. | Deposit date: | 2004-05-27 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Relation between tRNase activity and the structure of colicin D according to X-ray crystallography Biochem.Biophys.Res.Commun., 322, 2004
|
|
1IPJ
| CRYSTAL STRUCTURES OF RECOMBINANT AND NATIVE SOYBEAN BETA-CONGLYCININ BETA HOMOTRIMERS COMPLEXES WITH N-ACETYL-D-GLUCOSAMINE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-CONGLYCININ, BETA CHAIN | Authors: | Maruyama, N, Adachi, M, Takahashi, K, Yagasaki, K, Kohno, M, Takenaka, Y, Okuda, E, Nakagawa, S, Mikami, B, Utsumi, S. | Deposit date: | 2001-05-16 | Release date: | 2002-05-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of recombinant and native soybean beta-conglycinin beta homotrimers. Eur.J.Biochem., 268, 2001
|
|
1IPK
| CRYSTAL STRUCTURES OF RECOMBINANT AND NATIVE SOYBEAN BETA-CONGLYCININ BETA HOMOTRIMERS | Descriptor: | BETA-CONGLYCININ, BETA CHAIN | Authors: | Maruyama, N, Adachi, M, Takahashi, K, Yagasaki, K, Kohno, M, Takenaka, Y, Okuda, E, Nakagawa, S, Mikami, B, Utsumi, S. | Deposit date: | 2001-05-16 | Release date: | 2002-05-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of recombinant and native soybean beta-conglycinin beta homotrimers. Eur.J.Biochem., 268, 2001
|
|
1TAB
| STRUCTURE OF THE TRYPSIN-BINDING DOMAIN OF BOWMAN-BIRK TYPE PROTEASE INHIBITOR AND ITS INTERACTION WITH TRYPSIN | Descriptor: | BOWMAN-BIRK TYPE PROTEINASE INHIBITOR, TRYPSIN | Authors: | Tsunogae, Y, Tanaka, I, Yamane, T, Kikkawa, J.-I, Ashida, T, Ishikawa, C, Watanabe, K, Nakamura, S, Takahashi, K. | Deposit date: | 1990-10-15 | Release date: | 1992-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the trypsin-binding domain of Bowman-Birk type protease inhibitor and its interaction with trypsin. J.Biochem.(Tokyo), 100, 1986
|
|
1Y43
| crystal structure of aspergilloglutamic peptidase from Aspergillus niger | Descriptor: | Aspergillopepsin II heavy chain, Aspergillopepsin II light chain, SULFATE ION | Authors: | Sasaki, H, Nakagawa, A, Iwata, S, Muramatsu, T, Suganuma, M, Sawano, Y, Kojima, M, Kubota, K, Takahashi, K. | Deposit date: | 2004-11-30 | Release date: | 2005-12-13 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The three-dimensional structure of aspergilloglutamic peptidase from Aspergillus niger Proc.Jpn.Acad.,Ser.B, 80, 2004
|
|
7VUS
| Crystal structure of AlleyCat9 with 5-nitro-benzotriazole | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1H-benzotriazole, AlleyCat, ... | Authors: | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | Deposit date: | 2021-11-04 | Release date: | 2022-07-27 | Last modified: | 2022-10-26 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | NMR-guided directed evolution. Nature, 610, 2022
|
|
7VUU
| Crystal structure of AlleyCat10 with inhibitor | Descriptor: | 5-nitro-1H-benzotriazole, AlleyCat, CALCIUM ION | Authors: | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | Deposit date: | 2021-11-04 | Release date: | 2022-07-27 | Last modified: | 2022-10-26 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | NMR-guided directed evolution. Nature, 610, 2022
|
|
7VUR
| Crystal structure of AlleyCat9 with calcium but no inhibitor | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, AlleyCat, CALCIUM ION | Authors: | Margheritis, E, Takahashi, K, Korendovych, I.V, Tame, J.R.H. | Deposit date: | 2021-11-04 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | NMR-guided directed evolution. Nature, 610, 2022
|
|
7VUT
| Crystal structure of AlleyCat10 | Descriptor: | AlleyCat10, CALCIUM ION | Authors: | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | Deposit date: | 2021-11-04 | Release date: | 2022-07-27 | Last modified: | 2022-10-26 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | NMR-guided directed evolution. Nature, 610, 2022
|
|
8JPW
| Crystal Structure of Single-chain L-Glutamate Oxidase Mutant from Streptomyces sp. X-119-6 | Descriptor: | 2-OXOGLUTARIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, L-glutamate oxidase, ... | Authors: | Yamaguchi, H, Takahashi, K, Tatsumi, M, Tagami, U, Mizukoshi, T, Miyano, H, Sugiki, M. | Deposit date: | 2023-06-13 | Release date: | 2023-08-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Development of a novel single-chain l-glutamate oxidase from Streptomyces sp. X-119-6 by inserting flexible linkers Enzyme.Microb.Technol., 170, 2023
|
|