6G0L
| Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | Authors: | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | Deposit date: | 2018-03-19 | Release date: | 2018-08-22 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
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6FTX
| Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... | Authors: | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | Deposit date: | 2018-02-25 | Release date: | 2018-08-08 | Last modified: | 2018-10-17 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
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3W6X
| Yeast N-acetyltransferase Mpr1 in complex with CHOP | Descriptor: | (4S)-4-hydroxy-L-proline, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | Authors: | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | Deposit date: | 2013-02-25 | Release date: | 2013-08-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism Proc.Natl.Acad.Sci.USA, 110, 2013
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3W6S
| yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism | Descriptor: | HEXAETHYLENE GLYCOL, MAGNESIUM ION, MPR1 protein | Authors: | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | Deposit date: | 2013-02-21 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism Proc.Natl.Acad.Sci.USA, 110, 2013
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7WU9
| Cryo-EM structure of the human EP3-Gi signaling complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Suno, R, Sugita, Y, Morimoto, K, Iwasaki, K, Kato, T, Kobayashi, T. | Deposit date: | 2022-02-07 | Release date: | 2022-08-17 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.375 Å) | Cite: | Structural insights into the G protein selectivity revealed by the human EP3-G i signaling complex. Cell Rep, 40, 2022
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2AO5
| Crystal structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G-U base pairs | Descriptor: | 5'-R(*GP*GP*CP*GP*(5BU)P*GP*CP*GP*CP*U)-3', MAGNESIUM ION | Authors: | Utsunomiya, R, Suto, K, Balasundaresan, D, Fukamizu, A, Kumar, P.K, Mizuno, H. | Deposit date: | 2005-08-12 | Release date: | 2006-03-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G.U base pairs. Acta Crystallogr.,Sect.D, 62, 2006
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5WQC
| Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8. | Descriptor: | N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, ... | Authors: | Suno, R, Hirata, K, Yamashita, K, Tsujimoto, H, Sasanuma, M, Horita, S, Yamamoto, M, Rosenbaum, D.M, Iwata, S, Shimamura, T, Kobayashi, T. | Deposit date: | 2016-11-25 | Release date: | 2017-11-29 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA Structure, 26, 2018
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5WS3
| Crystal structures of human orexin 2 receptor bound to the selective antagonist EMPA determined by serial femtosecond crystallography at SACLA | Descriptor: | N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, ... | Authors: | Suno, R, Kimura, K, Nakane, T, Yamashita, K, Wang, J, Fujiwara, T, Yamanaka, Y, Im, D, Tsujimoto, H, Sasanuma, M, Horita, S, Hirokawa, T, Nango, E, Tono, K, Kameshima, T, Hatsui, T, Joti, Y, Yabashi, M, Shimamoto, K, Yamamoto, M, Rosenbaum, D.M, Iwata, S, Shimamura, T, Kobayashi, T. | Deposit date: | 2016-12-05 | Release date: | 2017-12-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA. Structure, 26, 2018
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5YC8
| Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with NMS (Hg-derivative) | Descriptor: | MERCURY (II) ION, Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine | Authors: | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | Deposit date: | 2017-09-06 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor Nat. Chem. Biol., 14, 2018
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5ZK8
| Crystal structure of M2 muscarinic acetylcholine receptor bound with NMS | Descriptor: | Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine | Authors: | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | Deposit date: | 2018-03-23 | Release date: | 2018-11-21 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor Nat. Chem. Biol., 14, 2018
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5ZKB
| Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with AF-DX 384 | Descriptor: | Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-[2-[(2S)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxidanylidene-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide | Authors: | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | Deposit date: | 2018-03-23 | Release date: | 2018-11-21 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor Nat. Chem. Biol., 14, 2018
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5ZK3
| Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with QNB | Descriptor: | (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2 | Authors: | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | Deposit date: | 2018-03-23 | Release date: | 2018-11-21 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor Nat. Chem. Biol., 14, 2018
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5ZKC
| Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with NMS | Descriptor: | Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-methyl scopolamine | Authors: | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | Deposit date: | 2018-03-23 | Release date: | 2018-11-21 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor Nat. Chem. Biol., 14, 2018
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7BUP
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4EIW
| Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH | Authors: | Suno, R, Niwa, H, Tsuchiya, D, Yoshida, M, Morikawa, K. | Deposit date: | 2012-04-06 | Release date: | 2012-06-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure of the whole cytosolic region of ATP-dependent protease FtsH Mol.Cell, 22, 2006
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2DHR
| Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FtsH | Authors: | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | Deposit date: | 2006-03-24 | Release date: | 2006-06-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
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2DI4
| Crystal structure of the FtsH protease domain | Descriptor: | Cell division protein ftsH homolog, MERCURY (II) ION | Authors: | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | Deposit date: | 2006-03-28 | Release date: | 2006-06-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
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2C7Z
| Plant enzyme crystal form II | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Leonard, G.A, Hunter, W.N. | Deposit date: | 2005-11-30 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation. J.Mol.Biol., 359, 2006
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2C7Y
| plant enzyme | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Germain, V, Bryce, J.H, Smith, S.M, Leonard, G.A, Hunter, W.N. | Deposit date: | 2005-11-30 | Release date: | 2006-05-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation. J.Mol.Biol., 359, 2006
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2VS0
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2VRZ
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3W91
| crystal structure of SeMet-labeled yeast N-acetyltransferase Mpr1 L87M mutant | Descriptor: | MPR1 protein | Authors: | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | Deposit date: | 2013-03-23 | Release date: | 2013-07-17 | Last modified: | 2013-08-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism Proc.Natl.Acad.Sci.USA, 110, 2013
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2IZ1
| 6PDH complexed with PEX inhibitor synchrotron data | Descriptor: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ... | Authors: | Sundaramoorthy, R, Iulek, J, Hunter, W.N. | Deposit date: | 2006-07-23 | Release date: | 2007-01-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274, 2007
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2IZ0
| PEX inhibitor-home data | Descriptor: | 1,2-ETHANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ... | Authors: | Sundaramoorthy, R, Iulek, J, Hunter, W.N. | Deposit date: | 2006-07-23 | Release date: | 2007-01-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274, 2007
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2IYO
| Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition | Descriptor: | 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, ... | Authors: | Sundaramoorthy, R, Iulek, J, Hunter, W.N. | Deposit date: | 2006-07-21 | Release date: | 2007-01-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates. FEBS J., 274, 2007
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