Author results

1HAB
  • Download 1hab
  • View 1hab
Molmil generated image of 1hab
CROSSLINKED HAEMOGLOBIN
分子名称:HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Schumacher, M.A., Dixon, M.M., Kluger, R., Jones, R.T., Brennan, R.G.
登録日1996-03-13
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric intermediates indicate R2 is the liganded hemoglobin end state.
Proc.Natl.Acad.Sci.USA, 94, 1997
1HAC
  • Download 1hac
  • View 1hac
Molmil generated image of 1hac
CROSSLINKED HAEMOGLOBIN
分子名称:HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Schumacher, M.A., Dixon, M.M., Kluger, R., Jones, R.T., Brennan, R.G.
登録日1996-03-13
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric intermediates indicate R2 is the liganded hemoglobin end state.
Proc.Natl.Acad.Sci.USA, 94, 1997
1WET
  • Download 1wet
  • View 1wet
Molmil generated image of 1wet
STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX
分子名称:DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE
著者Schumacher, M.A., Glasfeld, A., Zalkin, H., Brennan, R.G.
登録日1997-04-27
公開日1997-11-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
J.Biol.Chem., 272, 1997
2PUC
  • Download 2puc
  • View 2puc
Molmil generated image of 2puc
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE
著者Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
2PUD
  • Download 2pud
  • View 2pud
Molmil generated image of 2pud
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE
著者Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
3TPB
  • Download 3tpb
  • View 3tpb
Molmil generated image of 3tpb
STRUCTURE OF HIPA(S150A)
分子名称:Serine/threonine-protein kinase HipA, CHLORIDE ION, PHOSPHATE ION
著者schumacher, M.A.
登録日2011-09-07
公開日2012-10-03
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.
Cell Rep, 2, 2012
3TPD
  • Download 3tpd
  • View 3tpd
Molmil generated image of 3tpd
STRUCTURE OF PHIPA, MONOCLINIC FORM
分子名称:Serine/threonine-protein kinase HipA, CHLORIDE ION, PHOSPHATE ION
著者schumacher, M.A., link, T., Brennan, R.G.
登録日2011-09-07
公開日2012-10-03
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.
Cell Rep, 2, 2012
3TPE
  • Download 3tpe
  • View 3tpe
Molmil generated image of 3tpe
THE PHIPA P3121 STRUCTURE
分子名称:Serine/threonine-protein kinase HipA
著者Schumacher, M.A., Link, T., Brennan, R.G.
登録日2011-09-07
公開日2012-10-03
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.
Cell Rep, 2, 2012
3TPT
  • Download 3tpt
  • View 3tpt
Molmil generated image of 3tpt
STRUCTURE OF HIPA(D309Q) BOUND TO ADP
分子名称:Serine/threonine-protein kinase HipA, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者schumacher, M.A., link, T., Brennan, R.G.
登録日2011-09-08
公開日2012-10-03
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.
Cell Rep, 2, 2012
3TPV
  • Download 3tpv
  • View 3tpv
Molmil generated image of 3tpv
STRUCTURE OF PHIPA BOUND TO ADP
分子名称:Serine/threonine-protein kinase HipA, ADENINE, SULFATE ION
著者Schumacher, M.A., Link, T.M., Brennan, R.G.
登録日2011-09-08
公開日2012-10-03
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.
Cell Rep, 2, 2012
4PQK
  • Download 4pqk
  • View 4pqk
Molmil generated image of 4pqk
C-TERMINAL DOMAIN OF DNA BINDING PROTEIN
分子名称:Maltose ABC transporter periplasmic protein, Truncated replication protein RepA, MALTOTRIOSE
著者Schumacher, M.A., Chinnam, N., Tonthat, N.K.
登録日2014-03-03
公開日2014-06-18
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.401 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PQL
  • Download 4pql
  • View 4pql
Molmil generated image of 4pql
N-TERMINAL DOMAIN OF DNA BINDING PROTEIN
分子名称:Truncated replication protein RepA, 1,2-ETHANEDIOL
著者Schumacher, M.A., Chinnam, N., Tonthat, N.K.
登録日2014-03-03
公開日2014-06-11
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.444 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PT7
  • Download 4pt7
  • View 4pt7
Molmil generated image of 4pt7
STRUCTURE OF INITIATOR
分子名称:Replication initiator A family protein, SULFATE ION
著者Schumacher, M.A.
登録日2014-03-10
公開日2014-06-25
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PTA
  • Download 4pta
  • View 4pta
Molmil generated image of 4pta
STRUCTURE OF MDR INITIATOR
分子名称:Replication initiator protein
著者Schumacher, M.A.
登録日2014-03-10
公開日2014-06-25
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.6003 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
1BD3
  • Download 1bd3
  • View 1bd3
Molmil generated image of 1bd3
STRUCTURE OF THE APO URACIL PHOSPHORIBOSYLTRANSFERASE, 2 MUTANT C128V
分子名称:URACIL PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION
著者Schumacher, M.A., Carter, D., Scott, D., Roos, D., Ullman, B., Brennan, R.G.
登録日1998-05-12
公開日1999-05-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
1BD4
  • Download 1bd4
  • View 1bd4
Molmil generated image of 1bd4
UPRT-URACIL COMPLEX
分子名称:URACIL PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION, URACIL
著者Schumacher, M.A., Carter, D., Scott, D., Roos, D., Ullman, B., Brennan, R.G.
登録日1998-05-12
公開日1999-05-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
1DBQ
  • Download 1dbq
  • View 1dbq
Molmil generated image of 1dbq
DNA-BINDING REGULATORY PROTEIN
分子名称:PURINE REPRESSOR, MAGNESIUM ION
著者Schumacher, M.A., Choi, K.Y., Lu, F., Zalkin, H., Brennan, R.G.
登録日1996-02-13
公開日1996-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of corepressor-mediated specific DNA binding by the purine repressor.
Cell(Cambridge,Mass.), 83, 1995
1DBR
  • Download 1dbr
  • View 1dbr
Molmil generated image of 1dbr
HYPOXANTHINE GUANINE XANTHINE
分子名称:HYPOXANTHINE GUANINE XANTHINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION
著者Schumacher, M.A., Carter, D., Roos, D., Ullman, B., Brennan, R.G.
登録日1996-02-13
公開日1997-12-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop.
Nat.Struct.Biol., 3, 1996
1DH3
  • Download 1dh3
  • View 1dh3
Molmil generated image of 1dh3
CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING
分子名称:DNA (5'-D(*CP*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), TRANSCRIPTION FACTOR CREB, MAGNESIUM ION
著者Schumacher, M.A., Goodman, R.H., Brennan, R.G.
登録日1999-11-27
公開日2000-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding
J.Biol.Chem., 275, 2000
1FZP
  • Download 1fzp
  • View 1fzp
Molmil generated image of 1fzp
CRYSTAL STRUCTURES OF SARA: A PLEIOTROPIC REGULATOR OF VIRULENCE GENES IN S. AUREUS
分子名称:5'-D(P*AP*TP*AP*TP*AP*TP*A)-3', STAPHYLOCOCCAL ACCESSORY REGULATOR A, CALCIUM ION
著者Schumacher, M.A., Hurlburt, B., Brennan, R.G.
登録日2000-10-03
公開日2001-01-22
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus.
Nature, 409, 2001
1G4Y
  • Download 1g4y
  • View 1g4y
Molmil generated image of 1g4y
1.60 A CRYSTAL STRUCTURE OF THE GATING DOMAIN FROM SMALL CONDUCTANCE POTASSIUM CHANNEL COMPLEXED WITH CALCIUM-CALMODULIN
分子名称:CALCIUM-ACTIVATED POTASSIUM CHANNEL RSK2, CALMODULIN, SULFATE ION, ...
著者Schumacher, M.A., Rivard, A., Bachinger, H.P., Adelman, J.P.
登録日2001-01-07
公開日2001-05-09
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Nature, 410, 2001
1J4X
  • Download 1j4x
  • View 1j4x
Molmil generated image of 1j4x
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX
分子名称:DUAL SPECIFICITY PROTEIN PHOSPHATASE 3, DDE(AHP)(TPO)G(PTR)VATR
著者Schumacher, M.A., Todd, J.L., Tanner, K.G., Denu, J.M.
登録日2001-12-13
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002
1JLR
  • Download 1jlr
  • View 1jlr
Molmil generated image of 1jlr
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE GTP COMPLEX 2 MUTANT C128V
分子名称:Uracil Phosphoribosyltransferase, PHOSPHATE ION, GUANOSINE-5'-TRIPHOSPHATE
著者Schumacher, M.A., Bashor, C.J., Otsu, K., Zu, S., Parry, R., Ulmman, B., Brennan, R.G.
登録日2001-07-16
公開日2002-01-10
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JLS
  • Download 1jls
  • View 1jls
Molmil generated image of 1jls
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE URACIL/CPR 2 MUTANT C128V
分子名称:Uracil phosphoribosyltransferase, PHOSPHATE ION, MAGNESIUM ION, ...
著者Schumacher, M.A., Bashor, C.J., Otsu, K., Zu, S., Parry, R., Ullman, B., Brennan, R.G.
登録日2001-07-16
公開日2002-01-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JT0
  • Download 1jt0
  • View 1jt0
Molmil generated image of 1jt0
CRYSTAL STRUCTURE OF A COOPERATIVE QACR-DNA COMPLEX
分子名称:QACA operator, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A., Miller, M.C., Grkovic, S., Brown, M.H., Skurray, R.A., Brennan, R.G.
登録日2001-08-20
公開日2002-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
EMBO J., 21, 2002