Author results

6BI6
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SOLUTION NMR STRUCTURE OF UNCHARACTERIZED PROTEIN YEJG
Descriptor:Uncharacterized protein YejG
Authors:Mohanty, B., Finn, T.J., Macindoe, I., Zhong, J., Patrick, W.M., Mackay, J.P.
Deposit date:2017-11-01
Release date:2018-11-07
Method:SOLUTION NMR
Cite:Solution NMR structure of uncharacterized protein YejG representing the first structure from PF13989
To Be Published
6BGG
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SOLUTION NMR STRUCTURES OF THE BRD3 ET DOMAIN IN COMPLEX WITH A CHD4 PEPTIDE
Descriptor:CHD4, Bromodomain-containing protein 3
Authors:Wai, D.C.C., Szyszka, T.N., Campbell, A.E., Kwong, C., Wilkinson-White, L., Silva, A.P.G., Low, J.K.K., Kwan, A.H., Gamsjaeger, R., Lu, B., Vakoc, C.R., Blobel, G.A., Mackay, J.P.
Deposit date:2017-10-28
Release date:2018-03-21
Last modified:2018-05-23
Method:SOLUTION NMR
Cite:The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.
J. Biol. Chem., 293, 2018
5L9F
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S. ENTERICA HISA MUTANT - D10G, G11D, DUP13-15, G44E, G102A
Descriptor:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, SULFATE ION
Authors:Guo, X., Soderholm, A., Selmer, M.
Deposit date:2016-06-10
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5L6U
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S. ENTERICA HISA MUTANT - D10G, DUP13-15, Q24L, G102A
Descriptor:HisA, SULFATE ION
Authors:Guo, X., Soderholm, A., Selmer, M.
Deposit date:2016-05-31
Release date:2017-04-19
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G5I
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S. ENTERICA HISA MUTANT D10G
Descriptor:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-25
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4W
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S. ENTERICA HISA MUTANT D7N, D10G, DUP13-15 (VVR) WITH SUBSTRATE PROFAR
Descriptor:HISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-17
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4E
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S. ENTERICA HISA MUTANT D10G, DUP13-15, Q24L, G102A, V106L
Descriptor:SULFATE ION, SODIUM ION, ACETIC ACID, ...
Authors:Soderholm, A., Guo, X., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-12
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2W
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S. ENTERICA HISA MUTANT D10G, G102A
Descriptor:SULFATE ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-14
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2I
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S. ENTERICA HISA MUTANT DUP13-15(VVR)
Descriptor:PHOSPHATE ION, SODIUM ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2H
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S. ENTERICA HISA WITH MUTATION L169R
Descriptor:SULFATE ION, GLYCEROL, SODIUM ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G1Y
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S. ENTERICA HISA MUTANT D10G, DUP13-15,V14:2M, Q24L, G102
Descriptor:SULFATE ION, GLYCEROL
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G1T
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S. ENTERICA HISA MUTANT DUP13-15, D10G
Descriptor:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-03-30
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AHI
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CRYSTAL STRUCTURE OF SALMONALLA ENTERICA HISA MUTANT D7N WITH PROFAR
Descriptor:1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, GLYCEROL, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, ...
Authors:Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
Deposit date:2015-02-06
Release date:2016-03-02
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structure and Mechanism of Hisa from Salmonella Enterica
To be Published
5AHF
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA HISA D7N WITH PROFAR
Descriptor:[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
Authors:Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
Deposit date:2015-02-05
Release date:2015-09-02
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5AHE
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA HISA
Descriptor:PHOSPHATE ION, SODIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
Deposit date:2015-02-05
Release date:2015-09-02
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5AC8
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S. ENTERICA HISA WITH MUTATIONS D10G, DUP13-15, G102A
Descriptor:SULFATE ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-12
Release date:2016-09-28
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AC7
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S. ENTERICA HISA WITH MUTATIONS D7N, D10G, DUP13-15
Descriptor:GLYCEROL, SODIUM ION, SULFATE ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-12
Release date:2016-09-28
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AB3
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S.ENTERICA HISA MUTANT D7N, D10G, DUP13-15, Q24L, G102A
Descriptor:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-07-31
Release date:2016-09-28
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5A5W
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA HISA D7N D176A WITH PROFAR
Descriptor:[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
Authors:Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
Deposit date:2015-06-23
Release date:2015-09-02
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
4YI7
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ANTHRANILATE BOUND AT ACTIVE SITE OF ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE FROM ACINETOBACTER (ANPRT; TRPD)
Descriptor:Anthranilate phosphoribosyltransferase, 2-AMINOBENZOIC ACID
Authors:Evans, G.L., Newton, M.S., Norris, G.E., Patrick, W.M.
Deposit date:2015-02-28
Release date:2015-09-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.853 Å)
Cite:Substrate inhibition of protein in tryptophan biosynthesis pathway redirects flux to aromatic catabolism in Acinetobacter baylyi ADP1.
To Be Published
4XBJ
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Y274F ALANINE RACEMASE FROM E. COLI INHIBITED BY L-ALA-P
Descriptor:Alanine racemase, biosynthetic, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID, ...
Authors:Squire, C.J., Yosaatmadja, Y., Patrick, W.M.
Deposit date:2014-12-17
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Y274F alanine racemase from E. coli
To Be Published
4WR3
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Y274F ALANINE RACEMASE FROM E. COLI
Descriptor:Alanine racemase, biosynthetic, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Squire, C.J., Yosaatmadja, Y., Patrick, W.M.
Deposit date:2014-10-23
Release date:2015-11-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Y274F alanine racemase from E. coli
To Be Published
4ITX
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P113S MUTANT OF E. COLI CYSTATHIONINE BETA-LYASE METC INHIBITED BY REACTION WITH L-ALA-P
Descriptor:Cystathionine beta-lyase MetC, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID, CALCIUM ION
Authors:Squire, C.J., Yosaatmadja, Y., Soo, V.W.C., Patrick, W.M.
Deposit date:2013-01-19
Release date:2014-12-24
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure and activity of P113S mutant of E. coli Cystathionine beta-lyase (MetC)
To be Published
4ITG
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P113S MUTANT OF E. COLI CYSTATHIONINE BETA-LYASE METC
Descriptor:Cystathionine beta-lyase MetC, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Squire, C.J., Yosaatmadja, Y., Soo, V.W.C., Patrick, W.M.
Deposit date:2013-01-18
Release date:2014-12-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:E. coli Cystathionine beta-lyase (MetC) P113S mutant
To be Published
4GTN
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STRUCTURE OF ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE FROM ACINETOBACTER BAYLYI
Descriptor:Anthranilate phosphoribosyltransferase
Authors:Ponniah, K., Nigon, L.V., Anderson, B.F., Norris, G.E., Patrick, W.M.
Deposit date:2012-08-28
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Structure of anthranilate phosphoribosyl transferase from acinetobacter baylyi
To be Published
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