1XBR
 
 | | T DOMAIN FROM XENOPUS LAEVIS BOUND TO DNA | | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*G P*TP*GP*AP*AP*AP* TP*T)-3'), PROTEIN (T PROTEIN) | | Authors: | Muller, C.W. | | Deposit date: | 1997-07-16 | | Release date: | 1998-01-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
Nature, 389, 1997
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1A3Q
 | | HUMAN NF-KAPPA-B P52 BOUND TO DNA | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52) | | Authors: | Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W. | | Deposit date: | 1998-01-23 | | Release date: | 1998-06-11 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
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5FJ8
 | | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 A | | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ... | | Authors: | Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W. | | Deposit date: | 2015-10-06 | | Release date: | 2015-11-25 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
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5FJ9
 | | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A | | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ... | | Authors: | Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W. | | Deposit date: | 2015-10-06 | | Release date: | 2015-11-25 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
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1H6F
 | | Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site | | Descriptor: | 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX3 | | Authors: | Coll, M, Muller, C.W. | | Deposit date: | 2001-06-13 | | Release date: | 2002-04-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10, 2002
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6YJ6
 | | Structure of the TFIIIC subcomplex tauA | | Descriptor: | Transcription factor tau 131 kDa subunit, Transcription factor tau 55 kDa subunit, Transcription factor tau 95 kDa subunit,Transcription factor tau 95 kDa subunit | | Authors: | Vorlaender, M.K, Muller, C.W. | | Deposit date: | 2020-04-02 | | Release date: | 2020-09-16 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of the TFIIIC subcomplex tau A provides insights into RNA polymerase III pre-initiation complex formation.
Nat Commun, 11, 2020
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1BG1
 | | TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX | | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*CP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR STAT3B) | | Authors: | Becker, S, Groner, B, Muller, C.W. | | Deposit date: | 1998-06-03 | | Release date: | 1999-01-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Three-dimensional structure of the Stat3beta homodimer bound to DNA.
Nature, 394, 1998
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5M64
 | | RNA Polymerase I elongation complex with A49 tandem winged helix domain | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-24 | | Release date: | 2016-12-21 | | Last modified: | 2025-12-17 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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2C9L
 | | Structure of the Epstein-Barr virus ZEBRA protein | | Descriptor: | 5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*CP *TP*CP*AP*TP*GP*AP*AP*GP*T)-3', 5'-D(*AP*CP*TP*TP*CP*AP*CP*TP*GP*AP *GP*TP*CP*AP*GP*TP*GP*CP*T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN | | Authors: | Petosa, C, Morand, P, Baudin, F, Moulin, M, Artero, J.B, Muller, C.W. | | Deposit date: | 2005-12-13 | | Release date: | 2006-02-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
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2BYM
 | | Histone fold heterodimer of the Chromatin Accessibility Complex | | Descriptor: | CADMIUM ION, CHRAC-14, CHRAC-16 | | Authors: | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | | Deposit date: | 2005-08-03 | | Release date: | 2005-11-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions.
Mol.Cell.Biol., 25, 2005
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2BYK
 | | Histone fold heterodimer of the Chromatin Accessibility Complex | | Descriptor: | CHRAC-14, CHRAC-16, SULFATE ION | | Authors: | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | | Deposit date: | 2005-08-03 | | Release date: | 2005-11-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions.
Mol.Cell.Biol., 25, 2005
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2C9N
 | | Structure of the Epstein-Barr virus ZEBRA protein at approximately 3. 5 Angstrom resolution | | Descriptor: | 5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP *T)-3', 5'-D(*CP*AP*TP*GP*AP*GP*TP*CP*AP*GP *T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN | | Authors: | Petosa, C, Morand, P, Baudin, F, Moulin, M, Artero, J.B, Muller, C.W. | | Deposit date: | 2005-12-13 | | Release date: | 2006-02-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
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1QGR
 | | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH) | | Descriptor: | PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) | | Authors: | Cingolani, G, Petosa, C, Weis, K, Muller, C.W. | | Deposit date: | 1999-05-04 | | Release date: | 1999-05-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
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1QGK
 | | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA | | Descriptor: | PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) | | Authors: | Cingolani, G, Petosa, C, Weis, K, Muller, C.W. | | Deposit date: | 1999-04-29 | | Release date: | 1999-05-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
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2YN2
 | | Huf protein - paralogue of the tau55 histidine phosphatase domain | | Descriptor: | FORMIC ACID, UNCHARACTERIZED PROTEIN YNL108C | | Authors: | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | | Deposit date: | 2012-10-11 | | Release date: | 2013-04-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Tfiiic.
J.Biol.Chem., 288, 2013
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2YN0
 | | tau55 histidine phosphatase domain | | Descriptor: | PHOSPHATE ION, TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT | | Authors: | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | | Deposit date: | 2012-10-11 | | Release date: | 2013-04-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Iiic.
J.Biol.Chem., 288, 2013
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9GDP
 | | Cryo-EM structure of Vibrio cholerae RNA polymerase holoenzyme bound to an ompU promoter DNA fragment and 5-mer RNA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. | | Deposit date: | 2024-08-06 | | Release date: | 2025-12-17 | | Last modified: | 2026-01-28 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Sci Adv, 12, 2026
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9GDS
 | | Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with ToxR and TcpP transcription factors and a toxT promoter DNA fragment | | Descriptor: | Cholera toxin transcriptional activator, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. | | Deposit date: | 2024-08-06 | | Release date: | 2025-12-17 | | Last modified: | 2026-01-28 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Sci Adv, 12, 2026
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9GDR
 | | Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with TcpP transcription factor and a toxT promoter DNA fragment | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. | | Deposit date: | 2024-08-06 | | Release date: | 2025-12-17 | | Last modified: | 2026-01-28 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Sci Adv, 12, 2026
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9GDQ
 | | Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with ToxR transcription factor and ompU promoter DNA | | Descriptor: | Cholera toxin transcriptional activator, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. | | Deposit date: | 2024-08-06 | | Release date: | 2025-12-17 | | Last modified: | 2026-01-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Sci Adv, 12, 2026
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9GDO
 | | Cryo-EM structure of Vibrio cholerae RNA polymerase holoenzyme bound to an ompU promoter DNA fragment | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. | | Deposit date: | 2024-08-06 | | Release date: | 2025-12-17 | | Last modified: | 2026-01-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Sci Adv, 12, 2026
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2J04
 | | The tau60-tau91 subcomplex of yeast transcription factor IIIC | | Descriptor: | HYPOTHETICAL PROTEIN YPL007C, YDR362CP | | Authors: | Mylona, A, Fernandez-Tornero, C, Legrand, P, Muller, C.W. | | Deposit date: | 2006-07-31 | | Release date: | 2006-10-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of the Tau60/Deltatau91 Subcomplex of Yeast Transcription Factor Iiic: Insights Into Preinitiation Complex Assembly
Mol.Cell, 24, 2006
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5AEM
 | | Structure of t131 N-terminal TPR array | | Descriptor: | TRANSCRIPTION FACTOR TAU 131 KDA SUBUNIT | | Authors: | Taylor, N.M.I, Muller, C.W. | | Deposit date: | 2015-01-05 | | Release date: | 2015-06-24 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Nat Commun, 6, 2015
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1ODH
 | | Structure of the GCM domain bound to DNA | | Descriptor: | 5'-D(*CP*GP*AP*TP*GP*CP*GP*GP*GP*TP *GP*CP*A)-3', 5'-D(*TP*GP*CP*AP*CP*CP*CP*GP*CP*AP *TP*CP*G)-3', MGCM1, ... | | Authors: | Cohen, S.X, Muller, C.W. | | Deposit date: | 2003-02-19 | | Release date: | 2003-04-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystal Structure of the Gcm Domain-DNA Complex: A DNA-Binding Domain with a Novel Fold and Mode of Target Site Recognition
Embo J., 22, 2003
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5FJA
 | | Cryo-EM structure of yeast RNA polymerase III at 4.7 A | | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ... | | Authors: | Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W. | | Deposit date: | 2015-10-06 | | Release date: | 2015-11-25 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.65 Å) | | Cite: | Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
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