Author results

3RQS
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CRYSTAL STRUCTURE OF HUMAN L-3- HYDROXYACYL-COA DEHYDROGENASE (EC1.1.1.35) FROM MITOCHONDRIA AT THE RESOLUTION 2.0 A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR487, MITOCHONDRIAL PROTEIN PARTNERSHIP
Descriptor:Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial, GLYCEROL
Authors:Kuzin, A., Su, M., Seetharaman, J., Patel, P., Xiao, R., Ciccosanti, C., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2011-04-28
Release date:2011-05-25
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Northeast Structural Genomics Consortium Target HR487
To be published
4PED
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MITOCHONDRIAL ADCK3 EMPLOYS AN ATYPICAL PROTEIN KINASE-LIKE FOLD TO ENABLE COENZYME Q BIOSYNTHES
Descriptor:Chaperone activity of bc1 complex-like, mitochondrial, SULFATE ION
Authors:Bingman, C.A., Smith, R., Joshi, S., Stefely, J.A., Reidenbach, A.G., Ulbrich, A., Oruganty, O., Floyd, B.J., Jochem, A., Saunders, J.M., Johnson, I.E., Wrobel, R.L., Barber, G.E., Lee, D., Li, S., Kannan, N., Coon, J.J., Pagliarini, D.J., Mitochondrial Protein Partnership (MPP)
Deposit date:2014-04-22
Release date:2014-11-19
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis.
Mol.Cell, 57, 2015
5I35
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STRUCTURE OF THE HUMAN MITOCHONDRIAL KINASE COQ8A R611K WITH AMPPNP (CEREBELLAR ATAXIA AND UBIQUINONE DEFICIENCY THROUGH LOSS OF UNORTHODOX KINASE ACTIVITY)
Descriptor:Atypical kinase ADCK3, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bingman, C.A., Stefely, J.A., Pagliarini, D.J., Mitochondrial Protein Partnership (MPP)
Deposit date:2016-02-09
Release date:2016-08-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
Mol.Cell, 63, 2016
2M2B
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NMR STRUCTURE OF THE RRM2 DOMAIN OF THE PROTEIN RBM10 FROM HOMO SAPIENS
Descriptor:RNA-binding protein 10
Authors:Serrano, P., Geralt, M., Dutta, S.K., Wuthrich, K., Wrobel, R.L., Makino, S., Misenhiemer, T.M., Markley, J.L., Fox, B.G., Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL), Mitochondrial Protein Partnership (MPP)
Deposit date:2012-12-17
Release date:2013-01-16
Method:SOLUTION NMR
Cite:NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens
To be Published
2LM4
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SOLUTION NMR STRUCTURE OF MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2 FROM SACCHAROMYCES CEREVISIAE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET YT682A
Descriptor:Succinate dehydrogenase assembly factor 2, mitochondrial
Authors:Eletsky, A., Winge, D.R., Lee, H., Lee, D., Kohan, E., Hamilton, K., Acton, T.B., Xiao, R., Everett, J.K., Prestegard, J.H., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2011-11-22
Release date:2012-01-04
Last modified:2013-01-30
Method:SOLUTION NMR
Cite:Solution NMR structure of yeast succinate dehydrogenase flavinylation factor sdh5 reveals a putative sdh1 binding site.
Biochemistry, 51, 2012
4RHP
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CRYSTAL STRUCTURE OF HUMAN COQ9 IN COMPLEX WITH A PHOSPHOLIPID, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR5043
Descriptor:Ubiquinone biosynthesis protein COQ9, mitochondrial, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE
Authors:Forouhar, F., Lew, S., Seetharaman, J., Wang, H., Lee, D., Kogan, S., Maglaqui, M., Xiao, R., Everett, J.K., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2014-10-02
Release date:2014-10-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
2LNA
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SOLUTION NMR STRUCTURE OF THE MITOCHONDRIAL INNER MEMBRANE DOMAIN (RESIDUES 164-251), FTSH_EXT, FROM THE PARAPLEGIN-LIKE PROTEIN AFG3L2 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6741A
Descriptor:AFG3-like protein 2
Authors:Ramelot, T.A., Yang, Y., Lee, H., Janua, H., Kohan, E., Shastry, R., Acton, T.B., Xiao, R., Everett, J.K., Prestegard, J.H., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2011-12-20
Release date:2012-01-25
Last modified:2013-10-30
Method:SOLUTION NMR
Cite:NMR structure and MD simulations of the AAA protease intermembrane space domain indicates peripheral membrane localization within the hexaoligomer.
Febs Lett., 587, 2013
2LTL
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SOLUTION NMR STRUCTURE OF NIFU-LIKE PROTEIN FROM SACCHAROMYCES CEREVISIAE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET YR313A
Descriptor:NifU-like protein, mitochondrial
Authors:Liu, G., Xiao, R., Hamilton, K., Janjua, H., Shastry, R., Kohan, E., Acton, T.B., Everett, J.K., Lee, H., Huang, Y.J., Montelione, G.T., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2012-05-29
Release date:2012-07-25
Last modified:2012-08-01
Method:SOLUTION NMR
Cite:Solution NMR Structure of NifU-like protein from Saccharomyces cerevisiae, Northeast Structural Genomics Consortium (NESG) Target YR313A
To be Published
2LTM
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SOLUTION NMR STRUCTURE OF NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR2876B
Descriptor:NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Authors:Liu, G., Xiao, R., Janjua, H., Hamilton, K., Shastry, R., Kohan, E., Acton, T.B., Everett, J.K., Lee, H., Huang, Y.J., Montelione, G.T., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2012-05-29
Release date:2012-07-25
Last modified:2012-08-01
Method:SOLUTION NMR
Cite:Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B
To be Published
2M5O
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SOLUTION NMR STRUCTURE CTD DOMAIN OF NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR2876C
Descriptor:NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Authors:Liu, G., Xiao, R., Janjua, H., Hamilton, K., Shastry, R., Kohan, E., Acton, T.B., Everett, J.K., Pederson, K., Huang, Y.J., Montelione, G.T., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2013-03-01
Release date:2013-05-01
Last modified:2013-05-08
Method:SOLUTION NMR
Cite:Solution NMR Structure CTD domain of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876C
To be Published
6AWL
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CRYSTAL STRUCTURE OF HUMAN COQ9
Descriptor:Ubiquinone biosynthesis protein COQ9, mitochondrial, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Bingman, C.A., Lohman, D.C., Smith, R.W., Pagliarini, D.J., Mitochondrial Protein Partnership (MPP)
Deposit date:2017-09-05
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis.
Mol. Cell, 73, 2019
4DMB
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X-RAY STRUCTURE OF HUMAN HEPATITUS C VIRUS NS5A-TRANSACTIVATED PROTEIN 2 AT THE RESOLUTION 1.9A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR6723
Descriptor:HD domain-containing protein 2, NITRATE ION, MAGNESIUM ION, ...
Authors:Kuzin, A., Su, M., Seetharaman, J., Patel, P., Xiao, R., Ciccosanti, C., Lee, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2012-02-07
Release date:2012-04-04
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Northeast Structural Genomics Consortium Target HR6723
To be Published