Author results

1WYD
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CRYSTAL STRUCTURE OF ASPARTYL-TRNA SYNTHETASE FROM SULFOLOBUS TOKODAII
Descriptor:hypothetical aspartyl-tRNA synthetase, CHLORIDE ION, SULFATE ION, ...
Authors:Maeda, Y., Hossain, M.T., Ubukata, S., Suzuki, K., Sekiguchi, T., Takenaka, A.
Deposit date:2005-02-12
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the nondiscriminating aspartyl-tRNA synthetase from the crenarchaeon Sulfolobus tokodaii strain 7 reveals the recognition mechanism for two different tRNA anticodons
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
1J1D
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CRYSTAL STRUCTURE OF THE 46KDA DOMAIN OF HUMAN CARDIAC TROPONIN IN THE CA2+ SATURATED FORM
Descriptor:Troponin C, Troponin T, Troponin I, ...
Authors:Takeda, S., Yamashita, A., Maeda, K., Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
1J1E
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CRYSTAL STRUCTURE OF THE 52KDA DOMAIN OF HUMAN CARDIAC TROPONIN IN THE CA2+ SATURATED FORM
Descriptor:Troponin C, Troponin T, Troponin I, ...
Authors:Takeda, S., Yamashita, A., Maeda, K., Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
1A2X
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COMPLEX OF TROPONIN C WITH A 47 RESIDUE (1-47) FRAGMENT OF TROPONIN I
Descriptor:TROPONIN C, TROPONIN I, CALCIUM ION
Authors:Vassylyev, D.G., Takeda, S., Wakatsuki, S., Maeda, K., Maeda, Y.
Deposit date:1998-01-13
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
2D3E
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CRYSTAL STRUCTURE OF THE C-TERMINAL FRAGMENT OF RABBIT SKELETAL ALPHA-TROPOMYOSIN
Descriptor:General control protein GCN4 and Tropomyosin 1 alpha chain
Authors:Nitanai, Y., Maeda, K., Oda, N., Minakata, S., Maeda, Y.
Deposit date:2005-09-27
Release date:2006-09-12
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of C-Terminal Fragment of Rabbit Skeletal Alpha-Tropomyosin; Crystallographic Evidence of Tropomyosin Bending
To be Published
2EFR
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CRYSTAL STRUCTURE OF THE C-TERMINAL TROPOMYOSIN FRAGMENT WITH N- AND C-TERMINAL EXTENSIONS OF THE LEUCINE ZIPPER AT 1.8 ANGSTROMS RESOLUTION
Descriptor:General control protein GCN4 and Tropomyosin 1 alpha chain
Authors:Minakata, S., Nitanai, Y., Maeda, K., Oda, N., Wakabayashi, K., Maeda, Y.
Deposit date:2007-02-23
Release date:2008-03-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
2EFS
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CRYSTAL STRUCTURE OF THE C-TERMINAL TROPOMYOSIN FRAGMENT WITH N- AND C-TERMINAL EXTENSIONS OF THE LEUCINE ZIPPER AT 2.0 ANGSTROMS RESOLUTION
Descriptor:General control protein GCN4 and Tropomyosin 1 alpha chain
Authors:Minakata, S., Nitanai, Y., Maeda, K., Oda, N., Wakabayashi, K., Maeda, Y.
Deposit date:2007-02-23
Release date:2008-03-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published
2ZGY
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PARM WITH GDP
Descriptor:Plasmid segregation protein parM, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Popp, D., Narita, A., Oda, T., Fujisawa, T., Matsuo, H., Nitanai, Y., Iwasa, M., Maeda, K., Onishi, H., Maeda, Y.
Deposit date:2008-01-30
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability
Embo J., 27, 2008
2ZGZ
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PARM WITH GMPPNP
Descriptor:Plasmid segregation protein parM, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Popp, D., Narita, A., Oda, T., Fujisawa, T., Matsuo, H., Nitanai, Y., Iwasa, M., Maeda, K., Onishi, H., Maeda, Y.
Deposit date:2008-01-30
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability
Embo J., 27, 2008
1IZN
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CRYSTAL STRUCTURE OF ACTIN FILAMENT CAPPING PROTEIN CAPZ
Descriptor:CapZ alpha-1 subunit, CapZ beta-1 subunit, NITRATE ION
Authors:Yamashita, A., Maeda, K., Maeda, Y.
Deposit date:2002-10-10
Release date:2003-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of CapZ: structural basis for actin filament barbed end capping
EMBO J., 22, 2003
1V7M
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HUMAN THROMBOPOIETIN FUNCTIONAL DOMAIN COMPLEXED TO NEUTRALIZING ANTIBODY TN1 FAB
Descriptor:Monoclonal TN1 Fab Light Chain, Monoclonal TN1 Fab Heavy Chain, Thrombopoietin
Authors:Feese, M.D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Kato, T., Miyazaki, H., Kuroki, R.
Deposit date:2003-12-18
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
Proc.Natl.Acad.Sci.USA, 101, 2004
1V7N
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HUMAN THROMBOPOIETIN FUNCTIONAL DOMAIN COMPLEXED TO NEUTRALIZING ANTIBODY TN1 FAB
Descriptor:Monoclonal TN1 Fab Light Chain, Monoclonal TN1 Fab Heavy Chain, Thrombopoietin
Authors:Feese, M.D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Kato, T., Miyazaki, H., Kuroki, R.
Deposit date:2003-12-18
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
Proc.Natl.Acad.Sci.USA, 101, 2004
3Q9T
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CRYSTAL STRUCTURE ANALYSIS OF FORMATE OXIDASE
Descriptor:Choline dehydrogenase and related flavoproteins, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(8-formyl-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Doubayashi, D., Ootake, T., Maeda, Y., Oki, M., Tokunaga, Y., Sakurai, A., Nagaosa, Y., Mikami, B., Uchida, H.
Deposit date:2011-01-09
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Formate oxidase, an enzyme of the glucose-methanol-choline oxidoreductase family, has a His-Arg pair and 8-formyl-FAD at the catalytic site
Biosci.Biotechnol.Biochem., 75, 2011
3WQT
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STAPHYLOCOCCUS AUREUS FTSA COMPLEXED WITH AMPPNP
Descriptor:Cell division protein FtsA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Fujita, J., Maeda, Y., Miyazaki, Y., Inoue, T., Matsumura, H.
Deposit date:2014-02-01
Release date:2014-10-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of FtsA from Staphylococcus aureus
FEBS Lett., 588, 2014
3WQU
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STAPHYLOCOCCUS AUREUS FTSA COMPLEXED WITH ATP
Descriptor:Cell division protein FtsA, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Fujita, J., Maeda, Y., Miyazaki, Y., Inoue, T., Matsumura, H.
Deposit date:2014-02-01
Release date:2014-10-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of FtsA from Staphylococcus aureus
FEBS Lett., 588, 2014
5H5G
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STAPHYLOCOCCUS AUREUS FTSZ-GDP IN T AND R STATES
Descriptor:Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION
Authors:Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H.
Deposit date:2016-11-05
Release date:2017-05-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
5H5H
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STAPHYLOCOCCUS AUREUS FTSZ-GDP R29A MUTANT IN T STATE
Descriptor:Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION
Authors:Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H.
Deposit date:2016-11-05
Release date:2017-05-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
5H5I
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STAPHYLOCOCCUS AUREUS FTSZ-GDP R29A MUTANT IN R STATE
Descriptor:Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Fujita, J., Harada, R., Maeda, Y., Saito, Y., Mizohata, E., Inoue, T., Shigeta, Y., Matsumura, H.
Deposit date:2016-11-05
Release date:2017-05-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus
J. Struct. Biol., 198, 2017
5TNO
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DISCOVERY OF NOVEL AMINOBENZISOXAZOLE DERIVATIVES AS ORALLY AVAILABLE FACTOR IXA INHIBITORS
Descriptor:Coagulation factor IX, UNKNOWN LIGAND, SODIUM ION, ...
Authors:Sakurada, I., Endo, T., Hikita, K., Hirabayashi, T., Hosaka, Y., Kato, Y., Maeda, Y., Matsumoto, S., Mizuno, T., Nagasue, H., Nishimura, T., Shimada, S., Shinozaki, M., Taguchi, K., Takeuchi, K., Yokoyama, T., Hruza, A., Reichert, P., Zhang, T., Wood, H.B., Nakao, K., Furusako, S.
Deposit date:2016-10-14
Release date:2017-04-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5TNT
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DISCOVERY OF NOVEL AMINOBENZISOXAZOLE DERIVATIVES AS ORALLY AVAILABLE FACTOR IXA INHIBITORS
Descriptor:Coagulation factor IX, N-[(1S,4S,7R)-2-(3-amino-4-chloro[1,2]oxazolo[5,4-c]pyridin-7-yl)-2-azabicyclo[2.2.1]heptan-7-yl]-2-chloro-4-(3-methyl-1H-1,2,4-triazol-1-yl)benzamide, SODIUM ION, ...
Authors:Sakurada, I., Endo, T., Hikita, K., Hirabayashi, T., Hosaka, Y., Kato, Y., Maeda, Y., Matsumoto, S., Mizuno, T., Nagasue, A., Nishimura, T., Shimada, S., Shinozaki, M., Taguchi, K., Takeuchi, K., Yokoyama, T., Hruza, A., Reichert, P., Zhang, T., Wood, H.B., Nakao, K., Furusako, S.
Deposit date:2016-10-14
Release date:2017-04-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
1YWN
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VEGFR2 IN COMPLEX WITH A NOVEL 4-AMINO-FURO[2,3-D]PYRIMIDINE
Descriptor:Vascular endothelial growth factor receptor 2, N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA
Authors:Miyazaki, Y., Matsunaga, S., Tang, J., Maeda, Y., Nakano, M., Philippe, R.J., Shibahara, M., Liu, W., Sato, H., Wang, L., Nolte, R.T.
Deposit date:2005-02-18
Release date:2005-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
3AA0
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CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH THE CP-BINDING MOTIF DERIVED FROM CARMIL
Descriptor:F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, 21mer peptide from Leucine-rich repeat-containing protein 16A, ...
Authors:Takeda, S., Minakata, S., Narita, A., Kitazawa, M., Yamakuni, T., Maeda, Y., Nitanai, Y.
Deposit date:2009-11-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
3AA1
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CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH THE CP-BINDING MOTIF DERIVED FROM CKIP-1
Descriptor:F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, 23mer peptide from Pleckstrin homology domain-containing family O member 1, ...
Authors:Takeda, S., Minakata, S., Narita, A., Kitazawa, M., Yamakuni, T., Maeda, Y., Nitanai, Y.
Deposit date:2009-11-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
3AA6
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CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH THE CP-BINDING MOTIF DERIVED FROM CD2AP
Descriptor:F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, 23mer peptide from CD2-associated protein, ...
Authors:Takeda, S., Minakata, S., Narita, A., Kitazawa, M., Yamakuni, T., Maeda, Y., Nitanai, Y.
Deposit date:2009-11-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
3AA7
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CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN
Descriptor:F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, BARIUM ION, ...
Authors:Takeda, S., Minakata, S., Narita, A., Kitazawa, M., Yamakuni, T., Maeda, Y., Nitanai, Y.
Deposit date:2009-11-11
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
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