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1D31
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BU of 1d31 by Molmil
THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS
Descriptor: DNA (5'-D(*CP*GP*CP*AP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Joshua-Tor, L, Frolow, F, Appella, E, Hope, H, Rabinovich, D, Sussman, J.L.
Deposit date:1991-04-25
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structures of bulge-containing DNA fragments.
J.Mol.Biol., 225, 1992
1GCB
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BU of 1gcb by Molmil
GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL)
Descriptor: GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ...
Authors:Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C.
Deposit date:1995-07-18
Release date:1995-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6.
Science, 269, 1995
3GCB
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BU of 3gcb by Molmil
GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454
Descriptor: GAL6, GLYCEROL, SULFATE ION
Authors:Joshua-Tor, L, Zheng, W, Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
1A6R
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BU of 1a6r by Molmil
GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A
Descriptor: GAL6, SULFATE ION
Authors:Joshua-Tor, L, Zheng, W, Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
1GSW
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BU of 1gsw by Molmil
CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSX
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSV
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Crystal structure of the P65 crystal form of photoactive yellow protein G47S mutant
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-08
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
6X46
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NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains)
Descriptor: Gametocyte-specific factor 1, ZINC ION
Authors:Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L.
Deposit date:2020-05-22
Release date:2021-03-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons.
Cell Rep, 34, 2021
7UX9
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BU of 7ux9 by Molmil
Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA)
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Ipsaro, J.J, Adams, D.W, Joshua-Tor, L.
Deposit date:2022-05-05
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
5T7B
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Argonaute-2 - 5'-(E)-vinylphosphonate 2'-O-methyl-uridine modified mrTTR guide RNA complex
Descriptor: PHENOL, Protein argonaute-2, RNA (UVP)UAUAGAGCAAGAACACUGUU
Authors:Elkayam, E, Joshua-Tor, L.
Deposit date:2016-09-02
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.529 Å)
Cite:Protein structure
To Be Published
2GXA
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Crystal structure of papillomavirus E1 hexameric helicase with ssDNA and MgADP
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Enemark, E.J, Joshua-Tor, L.
Deposit date:2006-05-08
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Mechanism of DNA translocation in a replicative hexameric helicase.
Nature, 442, 2006
3BTV
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Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S0)-[G301R]
Descriptor: Galactose/lactose metabolism regulatory protein GAL80
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-31
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
3BTU
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BU of 3btu by Molmil
Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S2) [E351K]
Descriptor: Galactose/lactose metabolism regulatory protein GAL80
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-30
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
8E29
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BU of 8e29 by Molmil
Human Dis3L2 in complex with hairpin C-U12
Descriptor: DIS3-like exonuclease 2, RNA hairpin C-U12
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E27
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BU of 8e27 by Molmil
RNA-free Human Dis3L2
Descriptor: DIS3-like exonuclease 2
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E28
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BU of 8e28 by Molmil
Human Dis3L2 in complex with hairpin A-GCU14
Descriptor: DIS3-like exonuclease 2, RNA hairpin A-GCU14
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
8E2A
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BU of 8e2a by Molmil
Human Dis3L2 in complex with hairpin D-U7
Descriptor: DIS3-like exonuclease 2, RNA hairpin D-U7
Authors:Meze, K, Thomas, D.R, Joshua-Tor, L.
Deposit date:2022-08-14
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A shape-shifting nuclease unravels structured RNA.
Nat.Struct.Mol.Biol., 30, 2023
4O9D
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BU of 4o9d by Molmil
Structure of Dos1 propeller
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Rik1-associated factor 1
Authors:Kuscu, C, Schalch, T, Joshua-Tor, L.
Deposit date:2014-01-02
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PMW
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Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Descriptor: DIS3-like exonuclease 2, MAGNESIUM ION, U-U-U-U-U-U-U-U-U-U-U-U-U-U
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2014-05-22
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
Nature, 514, 2014
3BTS
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BU of 3bts by Molmil
Crystal structure of a ternary complex of the transcriptional repressor Gal80p (Gal80S0 [G301R]) and the acidic activation domain of Gal4p (aa 854-874) from Saccharomyces cerevisiae with NAD
Descriptor: Galactose/lactose metabolism regulatory protein GAL80, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Regulatory protein GAL4
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-30
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
4KRF
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BU of 4krf by Molmil
Structure of Human Argonaute-1 let-7 complex
Descriptor: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
4KRE
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BU of 4kre by Molmil
Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
3G7L
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Chromodomain of Chp1 in complex with Histone H3K9me3 peptide
Descriptor: ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ...
Authors:Schalch, T, Joshua-Tor, L.
Deposit date:2009-02-10
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin
Mol.Cell, 34, 2009
1R6Z
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The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
Descriptor: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
Deposit date:2003-10-17
Release date:2004-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
1R9W
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Crystal Structure of the DNA-binding domain of the human papillomavirus type 18 (HPV-18) replication initiation protein E1
Descriptor: Replication protein E1
Authors:Auster, A.S, Joshua-Tor, L.
Deposit date:2003-10-31
Release date:2003-11-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding.
J.Biol.Chem., 279, 2004

 

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