Author results

5EFX
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CRYSTAL STRUCTURE OF RHO GTPASE REGULATOR
分子名称:Rho guanine nucleotide exchange factor 2
著者Jiang, Y., Ouyang, S., Liu, Z.J.
登録日2015-10-26
公開日2016-06-29
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding
Biochem.Biophys.Res.Commun., 471, 2016
1LNQ
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CRYSTAL STRUCTURE OF MTHK AT 3.3 A
分子名称:POTASSIUM CHANNEL RELATED PROTEIN, CALCIUM ION
著者Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., Mackinnon, R.
登録日2002-05-03
公開日2002-06-19
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
4LMM
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CRYSTAL STRUCTURE OF NHERF1 PDZ1 DOMAIN COMPLEXED WITH THE CXCR2 C-TERMINAL TAIL IN P21 SPACE GROUP
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, ACETIC ACID, CHLORIDE ION
著者Jiang, Y., Lu, G., Wu, Y., Brunzelle, J., Sirinupong, N., Li, C., Yang, Z.
登録日2013-07-10
公開日2014-01-15
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
4MPA
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CRYSTAL STRUCTURE OF NHERF1-CXCR2 SIGNALING COMPLEX IN P21 SPACE GROUP
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, C-X-C chemokine receptor type 2 chimera, ACETIC ACID, ...
著者Jiang, Y., Lu, G., Wu, Y., Brunzelle, J., Sirinupong, N., Li, C., Yang, Z.
登録日2013-09-12
公開日2014-01-15
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.097 Å)
主引用文献New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
4PQW
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CRYSTAL STRUCTURE OF PHOSPHOLIPASE C BETA 3 IN COMPLEX WITH PDZ1 OF NHERF1
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, CHLORIDE ION, NICKEL (II) ION
著者Jiang, Y., Wang, S., Holcomb, J., Trescott, L., Guan, X., Hou, Y., Brunzelle, J., Sirinupong, N., Li, C., Yang, Z.
登録日2014-03-04
公開日2014-04-02
最終更新日2014-04-23
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer.
Biochem.Biophys.Res.Commun., 446, 2014
2L5F
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SOLUTION STRUCTURE OF THE TANDEM WW DOMAINS FROM HYPA/FBP11
分子名称:Pre-mRNA-processing factor 40 homolog A
著者Jiang, Y., Hu, H.
登録日2010-11-01
公開日2011-05-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Interaction with polyglutamine expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA)
To be Published
5H1Y
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CRYSTAL STRUCTURE OF THE DDX41 DEAD DOMAIN IN COMPLEX WITH SO42- AND MG2+
分子名称:Probable ATP-dependent RNA helicase DDX41, SULFATE ION, MAGNESIUM ION
著者Jiang, Y., Ouyang, S., Liu, Z.J.
登録日2016-10-13
公開日2017-01-18
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural and functional analyses of human DDX41 DEAD domain
Protein Cell, 8, 2017
5XJ1
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CRYSTAL STRUCTURE OF SPRLMCD
分子名称:Uncharacterized RNA methyltransferase SP_1029, GLYCEROL, HEXAETHYLENE GLYCOL, ...
著者Jiang, Y., Gong, Q.
登録日2017-04-28
公開日2017-11-01
実験手法X-RAY DIFFRACTION (1.753 Å)
主引用文献Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE, 12, 2017
5XJ2
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STRUCTURE OF SPRLMCD WITH U747 RNA
分子名称:Uncharacterized RNA methyltransferase SP_1029, RNA (5'-R(*GP*GP*CP*AP*CP*GP*UP*GP*CP*U)-3'), ZINC ION, ...
著者Jiang, Y., Gong, Q.
登録日2017-04-28
公開日2017-11-01
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE, 12, 2017
1ID1
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CRYSTAL STRUCTURE OF THE RCK DOMAIN FROM E.COLI POTASSIUM CHANNEL
分子名称:PUTATIVE POTASSIUM CHANNEL PROTEIN
著者Jiang, Y., Pico, A., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2001-04-02
公開日2001-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.
Neuron, 29, 2001
1ORQ
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X-RAY STRUCTURE OF A VOLTAGE-DEPENDENT POTASSIUM CHANNEL IN COMPLEX WITH AN FAB
分子名称:6E1 Fab light chain, 6E1 Fab heavy chain, potassium channel, ...
著者Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2003-03-14
公開日2003-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
1ORS
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X-RAY STRUCTURE OF THE KVAP POTASSIUM CHANNEL VOLTAGE SENSOR IN COMPLEX WITH AN FAB
分子名称:33H1 Fab light chain, 33H1 Fab heavy chain, potassium channel
著者Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2003-03-14
公開日2003-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
1TFE
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DIMERIZATION DOMAIN OF EF-TS FROM T. THERMOPHILUS
分子名称:ELONGATION FACTOR TS
著者Jiang, Y., Nock, S., Nesper, M., Sprinzl, M., Sigler, P.B.
登録日1996-04-16
公開日1996-11-08
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and importance of the dimerization domain in elongation factor Ts from Thermus thermophilus.
Biochemistry, 35, 1996
2LJ0
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THE THIRD SH3 DOMAIN OF R85FL
分子名称:Sorbin and SH3 domain-containing protein 1
著者Jiang, Y., Hu, H.
登録日2011-09-02
公開日2012-09-05
実験手法SOLUTION NMR
主引用文献Structure Basis for the Recognition of Ataxin-7 PRR with R85FL SH3 Domain
To be Published
2LJ1
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THE THIRD SH3 DOMAIN OF R85FL WITH ATAXIN-7 PRR
分子名称:Sorbin and SH3 domain-containing protein 1
著者Jiang, Y., Hu, H.
登録日2011-09-02
公開日2012-09-05
実験手法SOLUTION NMR
主引用文献Structure Basis for the Recognition of Ataxin-7 PRR with R85FL SH3 Domain
To be Published
3QWV
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CRYSTAL STRUCTURE OF HISTONE LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH THE COFACTOR PRODUCT ADOHCY
分子名称:SET and MYND domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Jiang, Y., Sirinupong, N., Brunzelle, J., Yang, Z.
登録日2011-02-28
公開日2011-07-06
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.
Plos One, 6, 2011
3QWW
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CRYSTAL STRUCTURE OF HISTONE LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH THE METHYLTRANSFERASE INHIBITOR SINEFUNGIN
分子名称:SET and MYND domain-containing protein 2, SINEFUNGIN, ZINC ION
著者Jiang, Y., Sirinupong, N., Brunzelle, J., Yang, Z.
登録日2011-02-28
公開日2011-07-06
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.
Plos One, 6, 2011
4O6F
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STRUCTURAL BASIS OF ESTROGEN RECEPTOR ALPHA METHYLATION MEDIATED BY HISTONE METHYLTRANSFERASE SMYD2
分子名称:N-lysine methyltransferase SMYD2, Estrogen receptor, ZINC ION, ...
著者Jiang, Y., Trescott, L., Holcomb, J., Brunzelle, J., Sirinupong, N., Shi, X., Yang, Z.
登録日2013-12-20
公開日2014-03-26
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
5X72
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH (RAC)-P9
分子名称:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, (2S)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
著者Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
登録日2017-02-23
公開日2017-10-04
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
5X73
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH R-P9
分子名称:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
著者Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
登録日2017-02-23
公開日2017-10-04
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
5X74
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THE CRYSTAL STRUCTURE PDE DELTA IN COMPLEX WITH COMPOUND (R, R)-1G
分子名称:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one
著者Jiang, Y., Zhuang, C., Chen, L., Wang, R., Wang, F., Sheng, C.
登録日2017-02-23
公開日2017-10-04
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
4N6X
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CRYSTAL STRUCTURE OF THE CHEMOKINE RECEPTOR CXCR2 IN COMPLEX WITH THE FIRST PDZ DOMAIN OF NHERF1
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein, CHLORIDE ION
著者Lu, G., Wu, Y., Jiang, Y., Brunzelle, J., Sirinupong, N., Li, C., Yang, Z.
登録日2013-10-14
公開日2014-01-15
実験手法X-RAY DIFFRACTION (1.051 Å)
主引用文献New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
5BOB
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CRYSTAL STRUCTURE OF THE MENINGITIS PATHOGEN STREPTOCOCCUS SUIS ADHESION FHB
分子名称:Translation initiation factor 2 (IF-2 GTPase), GLYCEROL
著者Jiang, Y., Zhang, C., Yu, Y.
登録日2015-05-27
公開日2015-11-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Expression, purification, crystallization and structure determination of the N terminal domain of Fhb, a factor H binding protein from Streptococcus suis.
Biochem.Biophys.Res.Commun., 466, 2015
3K04
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK MUTANT, NAK-DTPP, NA+ COMPLEX
分子名称:Potassium channel protein NaK, (4S)-2-METHYL-2,4-PENTANEDIOL, SODIUM ION
著者Jiang, Y., Derebe, M.G.
登録日2009-09-24
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore.
Proc.Natl.Acad.Sci.USA, 108, 2011
3K06
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK MUTANT, NAK-NTPP, K+ COMPLEX
分子名称:Potassium channel protein NaK, (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION
著者Jiang, Y., Derebe, M.G.
登録日2009-09-24
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore.
Proc.Natl.Acad.Sci.USA, 108, 2011