3QWV

Crystal structure of histone lysine methyltransferase SmyD2 in complex with the cofactor product AdoHcy

Summary for 3QWV

Entry DOI	10.2210/pdb3qwv/pdb
Descriptor	SET and MYND domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (4 entities in total)
Functional Keywords	methyltransferase, hsp90, transferase
Biological source	Mus musculus (mouse)
Cellular location	Cytoplasm, cytosol: Q8R5A0
Total number of polymer chains	1
Total formula weight	50222.67
Authors	Jiang, Y.,Sirinupong, N.,Brunzelle, J.,Yang, Z. (deposition date: 2011-02-28, release date: 2011-07-06, Last modification date: 2024-02-21)
Primary citation	Jiang, Y.,Sirinupong, N.,Brunzelle, J.,Yang, Z. Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain. Plos One, 6:e21640-e21640, 2011 Cited by PubMed: 21738746 DOI: 10.1371/journal.pone.0021640 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation