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1FRD
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MOLECULAR STRUCTURE OF THE OXIDIZED, RECOMBINANT, HETEROCYST (2FE-2S) FERREDOXIN FROM ANABAENA 7120 DETERMINED TO 1.7 ANGSTROMS RESOLUTION
Descriptor:HETEROCYST [2FE-2S] FERREDOXIN, FE2/S2 (INORGANIC) CLUSTER
Authors:Jacobson, B.L., Chae, Y.K., Markley, J.L., Rayment, I., Holden, H.M.
Deposit date:1993-04-14
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular structure of the oxidized, recombinant, heterocyst [2Fe-2S] ferredoxin from Anabaena 7120 determined to 1.7-A resolution.
Biochemistry, 32, 1993
2NNQ
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CRYSTAL STRUCTURE OF HUMAN ADIPOCYTE FATTY ACID BINDING PROTEIN IN COMPLEX WITH ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID
Descriptor:Fatty acid-binding protein, adipocyte, SULFATE ION, ...
Authors:Jacobson, B.L.
Deposit date:2006-10-24
Release date:2007-06-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).
Bioorg.Med.Chem.Lett., 17, 2007
2AYW
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN TRYPSIN AND A DESIGNED SYNTHETIC HIGHLY POTENT INHIBITOR IN THE PRESENCE OF BENZAMIDINE AT 0.97 A RESOLUTION
Descriptor:Cationic trypsin, CALCIUM ION, 2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID, ...
Authors:Sherawat, M., Kaur, P., Perbandt, M., Betzel, C., Slusarchyk, W.A., Bisacchi, G.S., Chang, C., Jacobson, B.L., Einspahr, H.M., Singh, T.P.
Deposit date:2005-09-09
Release date:2006-01-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution.
Acta Crystallogr.,Sect.D, 63, 2007
4JZD
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STRUCTURE OF FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 2-{2-[(4-CARBAMIMIDOYLPHENYL)CARBAMOYL]-6-METHOXYPYRIDIN-3-YL}-5-{[(2S)-1-HYDROXY-3,3-DIMETHYLBUTAN-2-YL]CARBAMOYL}BENZOIC ACID
Descriptor:Factor VIIa (Heavy Chain), Factor VIIa (Light Chain), 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid, ...
Authors:Jacobson, B.L., Anumula, R.
Deposit date:2013-04-02
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.
Bioorg.Med.Chem.Lett., 23, 2013
2OJ9
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STRUCTURE OF IGF-1R KINASE DOMAIN COMPLEXED WITH A BENZIMIDAZOLE INHIBITOR
Descriptor:Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen), 3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE
Authors:Sack, J.S., Jacobson, B.L.
Deposit date:2007-01-12
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
Bioorg.Med.Chem.Lett., 17, 2007
1FTP
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THREE-DIMENSIONAL STRUCTURE OF THE MUSCLE FATTY-ACID-BINDING PROTEIN ISOLATED FROM THE DESERT LOCUST, SCHISTOCERCA GREGARIA
Descriptor:MUSCLE FATTY ACID BINDING PROTEIN
Authors:Holden, H.M., Haunerland, N.H.
Deposit date:1994-07-06
Release date:1994-12-20
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of the muscle fatty-acid-binding protein isolated from the desert locust Schistocerca gregaria.
Biochemistry, 33, 1994
1SBP
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1.7 ANGSTROMS REFINED STRUCTURE OF SULFATE-BINDING PROTEIN INVOLVED IN ACTIVE TRANSPORT AND NOVEL MODE OF SULFATE BINDING
Descriptor:SULFATE-BINDING PROTEIN, SULFATE ION
Authors:Sack, J.S., Quiocho, F.A.
Deposit date:1993-07-19
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dominant role of local dipoles in stabilizing uncompensated charges on a sulfate sequestered in a periplasmic active transport protein.
Protein Sci., 2, 1993