5FU6
| NOT module of the human CCR4-NOT complex (Crystallization mutant) | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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3RW6
| Structure of nuclear RNA export factor TAP bound to CTE RNA | Descriptor: | Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA | Authors: | Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E. | Deposit date: | 2011-05-07 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat.Struct.Mol.Biol., 18, 2011
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3RW7
| Structure of N-terminal domain of nuclear RNA export factor TAP | Descriptor: | Nuclear RNA export factor 1 | Authors: | Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J. | Deposit date: | 2011-05-07 | Release date: | 2011-08-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat.Struct.Mol.Biol., 18, 2011
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5J3Q
| Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex | Descriptor: | Edc1, mRNA-decapping enzyme subunit 1 | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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5FU7
| drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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4CZW
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4CZX
| Complex of Neurospora crassa PAN2 (WD40) with PAN3 (C-TERM) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ... | Authors: | Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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4CZV
| Structure of the Neurospora crassa Pan2 WD40 domain | Descriptor: | CHLORIDE ION, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2 | Authors: | Peter, D, Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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4CZY
| Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ... | Authors: | Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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1FO1
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1FT8
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2B9Z
| Solution structure of FHV B2, a viral suppressor of RNAi | Descriptor: | B2 protein | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2005-10-13 | Release date: | 2005-11-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. Embo Rep., 6, 2005
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4CRW
| Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G) | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | Authors: | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-03-01 | Release date: | 2014-05-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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5J3Y
| Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex | Descriptor: | mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1 | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.288 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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5J3T
| Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex | Descriptor: | Edc1, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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1T2S
| Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2R
| Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1W3B
| The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | Descriptor: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | Authors: | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | Deposit date: | 2004-07-14 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha Nat.Struct.Mol.Biol., 11, 2004
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1YA0
| Crystal structure of the N-terminal domain of human SMG7 | Descriptor: | SMG-7 transcript variant 2, SULFATE ION | Authors: | Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E. | Deposit date: | 2004-12-17 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway. Mol.Cell, 17, 2005
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4D0K
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4GMJ
| Structure of human NOT1 MIF4G domain co-crystallized with CAF1 | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ... | Authors: | Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. | Deposit date: | 2012-08-16 | Release date: | 2012-10-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex Nucleic Acids Res., 40, 2012
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4GML
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2HWX
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2HWW
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2HWY
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