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4TZT
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BU of 4tzt by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ENOYL REDUCTASE (INHA) COMPLEXED WITH N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL- 5-OXOPYRROLIDINE-3-CARBOXAMIDE
Descriptor: (3S)-N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-07-10
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
1K8D
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BU of 1k8d by Molmil
crystal structure of the non-classical MHC class Ib Qa-2 complexed with a self peptide
Descriptor: 60S RIBOSOMAL PROTEIN, BETA-2-MICROGLOBULIN, QA-2 antigen
Authors:He, X, Tabaczewski, P, Ho, J, Stroynowski, I, Garcia, K.C.
Deposit date:2001-10-23
Release date:2001-12-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation.
Structure, 9, 2001
3CM8
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BU of 3cm8 by Molmil
A RNA polymerase subunit structure from virus
Descriptor: Polymerase acidic protein, peptide from RNA-directed RNA polymerase catalytic subunit
Authors:He, X, Zhou, J, Zeng, Z, Ma, J, Zhang, R, Rao, Z, Liu, Y.
Deposit date:2008-03-21
Release date:2008-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus
Nature, 454, 2008
4GYV
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BU of 4gyv by Molmil
Crystal structure of the DH domain of FARP2
Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2012-09-05
Release date:2013-03-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
1Q32
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BU of 1q32 by Molmil
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase
Descriptor: tyrosyl-DNA phosphodiesterase
Authors:He, X, Babaoglu, K, Price, A, Nitiss, K.C, Nitiss, J.L, White, S.W.
Deposit date:2003-07-28
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison
J.Mol.Biol., 372, 2007
4H6Y
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BU of 4h6y by Molmil
Crystal structure of the DH-PH-PH domain of FARP1
Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 1
Authors:He, X, Zhang, X.
Deposit date:2012-09-19
Release date:2013-03-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.09 Å)
Cite:Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
4GZU
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BU of 4gzu by Molmil
Crystal structure of the DH-PH-PH domain of FARP2
Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2012-09-06
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
3MKT
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BU of 3mkt by Molmil
Structure of a Cation-bound Multidrug and Toxin Compound Extrusion (MATE) transporter
Descriptor: Multi antimicrobial extrusion protein (Na(+)/drug antiporter) MATE-like MDR efflux pump
Authors:He, X, Szewczyk, P, Karyakin, A, Evin, M, Hong, W.-X, Zhang, Q, Chang, G.
Deposit date:2010-04-15
Release date:2010-09-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of a cation-bound multidrug and toxic compound extrusion transporter.
Nature, 467, 2010
3MKU
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BU of 3mku by Molmil
Structure of a Cation-bound Multidrug and Toxin Compound Extrusion (MATE) transporter
Descriptor: Multi antimicrobial extrusion protein (Na(+)/drug antiporter) MATE-like MDR efflux pump, RUBIDIUM ION
Authors:He, X, Szewczyk, P, Karyakin, A, Evin, M, Hong, W.-X, Zhang, Q, Chang, G.
Deposit date:2010-04-15
Release date:2010-09-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of a cation-bound multidrug and toxic compound extrusion transporter.
Nature, 467, 2010
8S9I
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BU of 8s9i by Molmil
Crystal structure of the gp32 C-terminal peptide/Dda/dT8
Descriptor: Dda helicase, dT8, gp32 C-terminal peptide
Authors:He, X, Yun, M.K, White, S.W.
Deposit date:2023-03-28
Release date:2023-06-28
Last modified:2025-01-22
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:Structural and functional insights into the interaction between the bacteriophage T4 DNA processing proteins gp32 and Dda.
Nucleic Acids Res., 52, 2024
3UPU
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BU of 3upu by Molmil
Crystal structure of the T4 Phage SF1B Helicase Dda
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*T)-3', ATP-dependent DNA helicase dda
Authors:He, X, Yun, M.K, Pemble IV, C.W, Kreuzer, K.N, Raney, K.D, White, S.W.
Deposit date:2011-11-18
Release date:2012-06-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:The T4 Phage SF1B Helicase Dda Is Structurally Optimized to Perform DNA Strand Separation.
Structure, 20, 2012
4TRJ
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BU of 4trj by Molmil
Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed with N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide, refined with new ligand restraints
Descriptor: (3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-06-17
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
2NSD
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BU of 2nsd by Molmil
Enoyl acyl carrier protein reductase InhA in complex with N-(4-methylbenzoyl)-4-benzylpiperidine
Descriptor: Enoyl-[acyl-carrier-protein] reductase, N-(4-METHYLBENZOYL)-4-BENZYLPIPERIDINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Ortiz de Montellano, P.R.
Deposit date:2006-11-03
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides.
Bioorg.Med.Chem., 15, 2007
4TZK
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BU of 4tzk by Molmil
Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed WITH 1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE
Descriptor: (3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-07-10
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
4U0J
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BU of 4u0j by Molmil
Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed with 1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE, refined with new ligand restraints
Descriptor: (3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-07-11
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
4U0K
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BU of 4u0k by Molmil
Crystal structure of Mycobacterium tuberculosis enoyl reductase complexed with N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide
Descriptor: (3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-07-11
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
8GME
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BU of 8gme by Molmil
Crystal structure of the gp32-Dda-dT17 complex
Descriptor: Dda helicase, ZINC ION, dT17, ...
Authors:He, X, Yun, M.K, White, S.W.
Deposit date:2023-03-24
Release date:2023-06-28
Last modified:2025-01-22
Method:X-RAY DIFFRACTION (4.98 Å)
Cite:Structural and functional insights into the interaction between the bacteriophage T4 DNA processing proteins gp32 and Dda.
Nucleic Acids Res., 52, 2024
6D2K
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BU of 6d2k by Molmil
Crystal structure of the FERM domain of mouse FARP2
Descriptor: FERM, ARHGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2018-04-13
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
4FA8
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BU of 4fa8 by Molmil
Multi-pronged modulation of cytokine signaling
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Secreted protein BARF1, ...
Authors:He, X, Shim, A.H.
Deposit date:2012-05-21
Release date:2012-08-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.
Proc.Natl.Acad.Sci.USA, 109, 2012
9U9B
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BU of 9u9b by Molmil
HBsAg in complex with HBC34 Fab
Descriptor: HBC34 Fab Heavy Chain, HBC34 Fab Light Chain, Middle S protein
Authors:Chen, L, He, X.
Deposit date:2025-03-27
Release date:2025-07-02
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural polymorphism of the antigenic loop in HBV surface antigen dictates binding of diverse neutralizing antibodies.
Cell Discov, 11, 2025
9JT1
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BU of 9jt1 by Molmil
Structure of HBsAg in complex with FabHBC and FabGC1102
Descriptor: Large envelope protein, heavy chain of GC1102, heavy chain of HBC, ...
Authors:Chen, L, He, X, Tao, W.
Deposit date:2024-10-01
Release date:2025-07-02
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural polymorphism of the antigenic loop in HBV surface antigen dictates binding of diverse neutralizing antibodies.
Cell Discov, 11, 2025
3HX3
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BU of 3hx3 by Molmil
Crystal structure of CRALBP mutant R234W
Descriptor: RETINAL, Retinaldehyde-binding protein 1
Authors:Stocker, A, He, X, Lobsiger, J.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HY5
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BU of 3hy5 by Molmil
Crystal structure of CRALBP
Descriptor: L(+)-TARTARIC ACID, RETINAL, Retinaldehyde-binding protein 1
Authors:Stocker, A, He, X, Lobsiger, J.
Deposit date:2009-06-22
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W.
Proc.Natl.Acad.Sci.USA, 106, 2009
9IYX
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BU of 9iyx by Molmil
Structure of HBV surface antigen determined in recombinant spherical subviral particle
Descriptor: Large envelope protein, ZINC ION
Authors:Chen, L, He, X.
Deposit date:2024-07-31
Release date:2025-01-15
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of small HBV surface antigen reveals mechanism of dimer formation.
Cell Discov, 11, 2025
9IYY
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BU of 9iyy by Molmil
Structure of HBsAg in complex with Fab H006
Descriptor: Large envelope protein, heavy chain of antibody H006 Fab, light chain of antibody H006 Fab
Authors:Chen, L, He, X.
Deposit date:2024-07-31
Release date:2025-07-02
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural polymorphism of the antigenic loop in HBV surface antigen dictates binding of diverse neutralizing antibodies.
Cell Discov, 11, 2025

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