Author results

1TRH
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TWO CONFORMATIONAL STATES OF CANDIDA RUGOSA LIPASE
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE
Authors:Grochulski, P., Cygler, M.
Deposit date:1993-11-18
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two conformational states of Candida rugosa lipase.
Protein Sci., 3, 1994
1CIY
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INSECTICIDAL TOXIN: STRUCTURE AND CHANNEL FORMATION
Descriptor:CRYIA(A)
Authors:Grochulski, P., Cygler, M.
Deposit date:1995-06-01
Release date:1997-01-27
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Bacillus thuringiensis CryIA(a) insecticidal toxin: crystal structure and channel formation.
J.Mol.Biol., 254, 1995
1CRL
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INSIGHTS INTO INTERFACIAL ACTIVATION FROM AN 'OPEN' STRUCTURE OF CANDIDA RUGOSA LIPASE
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE
Authors:Grochulski, P., Cygler, M.
Deposit date:1993-03-02
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Insights into interfacial activation from an open structure of Candida rugosa lipase.
J.Biol.Chem., 268, 1993
3RAR
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X-RAY STRUCTURE OF A BOUND PHOSPHONATE TRANSITION STATE ANALOG AND ENANTIOSELECTIVITY OF CANDIDA RUGOSA LIPASE TOWARD CHIRAL CARBOXYLIC ACIDS
Descriptor:Lipase 1, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Grochulski, P., Kazlauskas, R.
Deposit date:2011-03-28
Release date:2011-04-27
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Insights into the molecular basis of chiral acid recognition by Candida rugosa lipase from an X-ray crystal structure of a bound phosphonate transition state analog
Adv.Synth.Catal., 353, 2011
1CJL
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CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
Descriptor:PROCATHEPSIN L
Authors:Coulombe, R., Grochulski, P., Sivaraman, J., Cygler, M.
Deposit date:1996-07-24
Release date:1997-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
1MIR
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RAT PROCATHEPSIN B
Descriptor:PROCATHEPSIN B
Authors:Cygler, M., Sivaraman, J., Grochulski, P., Coulombe, R., Storer, A.C., Mort, J.S.
Deposit date:1996-01-12
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.
Structure, 4, 1996
1AJ5
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CALPAIN DOMAIN VI APO
Descriptor:CALPAIN
Authors:Cygler, M., Grochulski, P., Blanchard, H.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nat.Struct.Biol., 4, 1997
1DVI
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CALPAIN DOMAIN VI WITH CALCIUM BOUND
Descriptor:CALPAIN, CALCIUM ION
Authors:Cygler, M., Blanchard, H., Grochulski, P.
Deposit date:1997-05-15
Release date:1998-05-27
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nat.Struct.Biol., 4, 1997
1EUA
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SCHIFF BASE INTERMEDIATE IN KDPG ALDOLASE FROM ESCHERICHIA COLI
Descriptor:KDPG ALDOLASE, ACETATE ION, SULFATE ION, ...
Authors:Allard, J., Grochulski, P., Sygusch, J.
Deposit date:2000-04-14
Release date:2001-02-07
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Covalent intermediate trapped in 2-keto-3-deoxy-6- phosphogluconate (KDPG) aldolase structure at 1.95-A resolution.
Proc.Natl.Acad.Sci.USA, 98, 2001
1EUN
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STRUCTURE OF 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE FROM ESCHERICHIA COLI
Descriptor:KDPG ALDOLASE, SULFATE ION
Authors:Allard, J., Grochulski, P., Sygusch, J.
Deposit date:2000-04-17
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Covalent intermediate trapped in 2-keto-3-deoxy-6- phosphogluconate (KDPG) aldolase structure at 1.95-A resolution.
Proc.Natl.Acad.Sci.USA, 98, 2001
1F2E
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STRUCTURE OF SPHINGOMONAD, GLUTATHIONE S-TRANSFERASE COMPLEXED WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE
Authors:Nishio, T., Watanabe, T., Patel, A., Wang, Y., Lau, P.C.K., Grochulski, P., Li, Y., Cygler, M.
Deposit date:2000-05-24
Release date:2000-06-21
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Properties of a Sphingomonad and Marine Bacterium Beta-Class Glutathione S-Transferases and Crystal Structure of the Former Complex with Glutathione
To be published
1NP8
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18-K C-TERMINALLY TRUNUCATED SMALL SUBUNIT OF CALPAIN
Descriptor:Calcium-dependent protease, small subunit, CADMIUM ION
Authors:Leinala, E.K., Arthur, J.S., Grochulski, P., Davies, P.L., Elce, J.S., Jia, Z.
Deposit date:2003-01-17
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein
PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
2I1Q
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RADA RECOMBINASE IN COMPLEX WITH CALCIUM
Descriptor:DNA repair and recombination protein radA, MAGNESIUM ION, CALCIUM ION, ...
Authors:Qian, X., He, Y., Ma, X., Fodje, M.N., Grochulski, P., Luo, Y.
Deposit date:2006-08-14
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination.
J.Biol.Chem., 281, 2006
3H5X
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CRYSTAL STRUCTURE OF 2'-AMINO-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE BOUND TO NOROVIRUS GII RNA POLYMERASE
Descriptor:RNA dependent RNA polymerase, 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ...
Authors:Zamyatkin, D.F., Parra, F., Machin, A., Grochulski, P., Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
3H5Y
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NOROVIRUS POLYMERASE+PRIMER/TEMPLATE+CTP COMPLEX AT 6 MM MNCL2
Descriptor:RNA dependent RNA polymerase, 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ...
Authors:Zamyatkin, D.F., Parra, F., Machin, A., Grochulski, P., Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
4G54
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CRYSTAL STRUCTURE OF A PERIPLASMIC DOMAIN OF THE EPSAB FUSION PROTEIN OF THE VIBRIO VULNIFICUS TYPE II SECRETION SYSTEM
Descriptor:General Secretion Pathway Protein
Authors:Martynnowski, D., Grochulski, P., Howard, S.P.
Deposit date:2012-07-17
Release date:2013-01-30
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system.
Acta Crystallogr.,Sect.D, 69, 2013
4QPX
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NV POLYMERASE POST-INCORPORATION-LIKE COMPLEX
Descriptor:Polyprotein, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3'), RNA (5'-R(*U*AP*CP*CP*CP*GP*GP*G)-3'), ...
Authors:Zamyatkin, D.F., Parra, F., Grochulski, P., Ng, K.K.S.
Deposit date:2014-06-25
Release date:2015-04-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase.
Acta Crystallogr.,Sect.D, 70, 2014
4XBH
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SOLUBLE RABBIT NEPRILYSIN
Descriptor:Neprilysin, ZINC ION, PHOSPHATE ION, ...
Authors:Labiuk, S.L., Grochulski, P., Sygusch, J.
Deposit date:2014-12-16
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Structures of Soluble Rabbit Neutral Endopeptidase (Neprilysin) Complexed with Phosphoramidon and Thiorphan
To Be Published
4ZNG
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X-RAY CRYSTALLOGRAPHY OF RECOMBINANT LACTOCOCCUS LACTIS PROLIDASE
Descriptor:Prolidase, MANGANESE (II) ION, CACODYLATE ION, ...
Authors:Kgosisejo, O., Grochulski, P., Tanaka, T.
Deposit date:2015-05-04
Release date:2016-08-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:X-ray crystallography of recombinant Lactococcus lactis prolidase
To Be Published
4ZR5
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SOLUBLE RABBIT NEPRILYSIN IN COMPLEX WITH PHOSPHORAMIDON
Descriptor:Neprilysin, ZINC ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ...
Authors:Labiuk, S.L., Grochulski, P., Sygusch, J.
Deposit date:2015-05-11
Release date:2016-06-08
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.8016 Å)
Cite:Structures of Soluble Rabbit Neutral Endopeptidase (Neprilysin) Complexed with Phosphoramidon and Thiorphan
To Be Published
5V48
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SOLUBLE RABBIT NEPRILYSIN IN COMPLEX WITH THIORPHAN
Descriptor:Neprilysin, ZINC ION, (2-MERCAPTOMETHYL-3-PHENYL-PROPIONYL)-GLYCINE, ...
Authors:Labiuk, S.L., Grochulski, P., Sygusch, J.
Deposit date:2017-03-08
Release date:2018-03-14
Method:X-RAY DIFFRACTION (2.9965 Å)
Cite:Soluble rabbit neprilysin in complex with thiorphan
To Be Published
1LPN
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ANALOGS OF REACTION INTERMEDIATES IDENTIFY A UNIQUE SUBSTRATE BINDING SITE IN CANDIDA RUGOSA LIPASE
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Grochulski, P.G., Cygler, M.C.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase.
Biochemistry, 33, 1994
1LPO
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ANALOGS OF REACTION INTERMEDIATES IDENTIFY A UNIQUE SUBSTRATE BINDING SITE IN CANDIDA RUGOSA LIPASE
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Grochulski, P.G., Cygler, M.C.
Deposit date:1995-01-13
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase.
Biochemistry, 33, 1994
1LPP
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ANALOGS OF REACTION INTERMEDIATES IDENTIFY A UNIQUE SUBSTRATE BINDING SITE IN CANDIDA RUGOSA LIPASE
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Grochulski, P.G., Cygler, M.C.
Deposit date:1995-01-17
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase.
Biochemistry, 33, 1994
1LPM
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A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES
Descriptor:LIPASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Grochulski, P.G., Cygler, M.C.
Deposit date:1995-01-06
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A Structural Basis for the Chiral Preferences of Lipases
J.Am.Chem.Soc., 116, 1994
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