4G54
Crystal structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system
Summary for 4G54
| Entry DOI | 10.2210/pdb4g54/pdb |
| Descriptor | General Secretion Pathway Protein (2 entities in total) |
| Functional Keywords | type 2 secretion system protein, peptidoglycan-binding protein |
| Biological source | Vibrio vulnificus |
| Total number of polymer chains | 1 |
| Total formula weight | 29867.02 |
| Authors | Martynnowski, D.,Grochulski, P.,Howard, S.P. (deposition date: 2012-07-17, release date: 2013-01-30, Last modification date: 2024-10-09) |
| Primary citation | Martynowski, D.,Grochulski, P.,Howard, P.S. Structure of a periplasmic domain of the EpsAB fusion protein of the Vibrio vulnificus type II secretion system. Acta Crystallogr.,Sect.D, 69:142-149, 2013 Cited by PubMed Abstract: Vibrio vulnificus utilizes the type II secretion system (T2SS), culminating in a megadalton outer membrane complex called the secretin, to translocate extracellular proteins from the periplasmic space across the outer membrane. In Aeromonas hydrophila, the general secretion pathway proteins ExeA and ExeB form an inner membrane complex which interacts with peptidoglycan and is required for the assembly of the secretin composed of ExeD. In V. vulnificus, these two proteins are fused into one protein, EpsAB. Here, the crystal structure of a periplasmic domain of EpsAB (amino acids 333-584) solved by SAD phasing is presented. The crystals belonged to space group C2 and diffracted to 1.55 Å resolution. PubMed: 23385451DOI: 10.1107/S0907444912042710 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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