3RAR
X-ray structure of a bound phosphonate transition state analog and enantioselectivity of Candida rugosa lipase toward chiral carboxylic acids
Summary for 3RAR
| Entry DOI | 10.2210/pdb3rar/pdb |
| Descriptor | Lipase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | alpha/beta hydrolase fold, hydrolase, calcium binding, (rc, rp)-methyl[1-(methoxy)phenylmethyl]phosphonyl adduct at og of serine 209 |
| Biological source | Candida rugosa (yeast) |
| Total number of polymer chains | 1 |
| Total formula weight | 58075.79 |
| Authors | Grochulski, P.,Kazlauskas, R. (deposition date: 2011-03-28, release date: 2011-04-27, Last modification date: 2023-09-13) |
| Primary citation | Colton, I.J.,Yin, D.T.,Grochulski, P.,Kazlauskas, R.J. Insights into the molecular basis of chiral acid recognition by Candida rugosa lipase from an X-ray crystal structure of a bound phosphonate transition state analog Adv.Synth.Catal., 353:2529-2544, 2011 Cited by DOI: 10.1002/adsc.201100459PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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