Author results

1H15
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X-RAY CRYSTAL STRUCTURE OF HLA-DRA1*0101/DRB5*0101 COMPLEXED WITH A PEPTIDE FROM EPSTEIN BARR VIRUS DNA POLYMERASE
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DR BETA 1 CHAIN, ...
Authors:Lang, H., Jacobsen, H., Ikemizu, S., Andersson, C., Harlos, K., Madsen, L., Hjorth, P., Sondergaard, L., Svejgaard, A., Wucherpfennig, K., Stuart, D.I., Bell, J.I., Jones, E.Y., Fugger, L.
Deposit date:2002-07-02
Release date:2002-10-03
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
2XPG
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CRYSTAL STRUCTURE OF A MHC CLASS I-PEPTIDE COMPLEX
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:McMahon, R.M., Friis, L., Siebold, C., Friese, M.A., Fugger, L., Jones, E.Y.
Deposit date:2010-08-26
Release date:2011-04-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis
Acta Crystallogr.,Sect.D, 67, 2011
1UVQ
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CRYSTAL STRUCTURE OF HLA-DQ0602 IN COMPLEX WITH A HYPOCRETIN PEPTIDE
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, OREXIN, GLYCINE, ...
Authors:Siebold, C., Hansen, B.E., Wyer, J.R., Harlos, K., Esnouf, R.E., Svejgaard, A., Bell, J.I., Strominger, J.L., Jones, E.Y., Fugger, L.
Deposit date:2004-01-22
Release date:2004-02-05
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
2WBJ
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TCR COMPLEX
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DRB1-15 BETA CHAIN, ...
Authors:Harkiolaki, M., Holmes, S.L., Svendsen, P., Gregersen, J.W., Jensen, L.T., McMahon, R., Friese, M.A., van Boxel, G., Etzensperger, R., Tzartos, J.S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E.D., Palace, J., Esiri, M.M., van der Merwe, P.A., Jones, E.Y., Fugger, L.
Deposit date:2009-03-02
Release date:2009-04-07
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
3MFF
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1F1E8HU TCR
Descriptor:T cell receptor alpha chain, T cell receptor beta chain, GLYCEROL, ...
Authors:van Boxel, G.I., Holmes, S., Fugger, L., Jones, E.Y.
Deposit date:2010-04-02
Release date:2010-06-02
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:An alternative conformation of the T-cell receptor alpha constant region
J.Mol.Biol., 400, 2010
2C7U
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CONFLICTING SELECTIVE FORCES AFFECT CD8 T-CELL RECEPTOR CONTACT SITES IN AN HLA-A2 IMMUNODOMINANT HIV EPITOPE.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Iversen, A.K., Stewart-Jones, G., Learn, G.H., Christie, N., Sylvester-Hviid, C., Armitage, A.E., Kaul, R., Beattie, T., Lee, J.K., Li, Y., Chotiyarnwong, P., Dong, T., Xu, X., Luscher, M.A., MacDonald, K., Ullum, H., Klarlund-Pedersen, B., Skinhoj, P., Fugger, J.L., Buus, S., Mullins, J.I., Jones, E.Y., van der Merwe, P.A., McMichael, A.J.
Deposit date:2005-11-29
Release date:2006-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
5HEZ
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JAK2 KINASE (JH1 DOMAIN) MUTANT P1057A IN COMPLEX WITH TG101209
Descriptor:Tyrosine-protein kinase JAK2, CHLORIDE ION, ZINC ION, ...
Authors:Ultsch, M., Eigenbrot, C.
Deposit date:2016-01-06
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Sci Transl Med, 8, 2016
3GIV
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ANTIGEN PROCESSING INFLUENCES HIV-SPECIFIC CYTOTOXIC T LYMPHOCYTE IMMUNODOMINANCE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G., Iversen, A.K.N., Jones, E.Y.
Deposit date:2009-03-06
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
5V4M
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STRUCTURE OF HLA-DR15 WITH BOUND ALPHA3(135-145) PEPTIDE
Descriptor:HLA-DRA1, alpha3(135-145)-HLA-DRB1*15:01, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Petersen, J., Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
5V4N
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STRUCTURE OF HLA-DR1 WITH BOUND ALPHA3(135-145) PEPTIDE
Descriptor:HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01, N-ACETYL-D-GLUCOSAMINE
Authors:Petersen, J., Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
5VGD
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CRYSTAL STRUCTURE OF HLA-C*0501 IN COMPLEX WITH SAE
Descriptor:HLA class I histocompatibility antigen, Cw-5 alpha chain, Beta-2-microglobulin, ...
Authors:Gras, S., Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
5VGE
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CRYSTAL STRUCTURE OF HLA-C*07:02 IN COMPLEX WITH RYR PEPTIDE
Descriptor:cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain, ...
Authors:Mobbs, J.I., Vivian, J.P., Gras, S., Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-06-07
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017