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Crystal Structure of Swine Flu Virus NS1 Effector Domain from H1N1 Influenza A/California/07/2009
Descriptor:	Nonstructural protein 1
Authors:	Fremont, D.H, Yu, Y.Y.L, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2010-03-13
Release date:	2010-04-07
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal Structure of Swine Flu Virus NS1 Effector Domain from H1N1 Influenza A/California/07/2009 To be Published

2VAB

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, SENDAI VIRUS NUCLEOPROTEIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

2VAA

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

1VAC

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND CHICKEN OVALBUMIN
Descriptor:	BETA-2 MICROGLOBULIN, CHICKEN OVALBUMIN, MHC CLASS I H-2KB HEAVY CHAIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc.Natl.Acad.Sci.USA, 92, 1995

1VAD

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, YEAST ALPHA-GLUCOSIDASE
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc.Natl.Acad.Sci.USA, 92, 1995

3OQ3

Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
Descriptor:	1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:	Fremont, D.H, Lee, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2010-09-02
Release date:	2011-05-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor To be Published

1EYH

CRYSTAL STRUCTURE OF THE EPSIN N-TERMINAL HOMOLOGY (ENTH) DOMAIN AT 1.56 ANGSTROM RESOLUTION
Descriptor:	EPSIN
Authors:	Fremont, D.H.
Deposit date:	2000-05-06
Release date:	2000-06-07
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.56 Å)
Cite:	CRYSTAL STRUCTURE OF THE EPSIN N-TERMINAL HOMOLOGY (ENTH) DOMAIN AT 1.56 ANGSTROM RESOLUTION To be Published

1IEA

HISTOCOMPATIBILITY ANTIGEN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK
Authors:	Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
Deposit date:	1996-04-05
Release date:	1997-06-05
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996

1IEB

HISTOCOMPATIBILITY ANTIGEN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK, SULFATE ION
Authors:	Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
Deposit date:	1996-04-05
Release date:	1997-06-05
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996

1IAK

HISTOCOMPATIBILITY ANTIGEN I-AK
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AK
Authors:	Fremont, D.H, Unanue, E.R, Hendrickson, W.A.
Deposit date:	1997-11-18
Release date:	1998-04-15
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity, 8, 1998

1KT2

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ...
Authors:	Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
Deposit date:	2002-01-15
Release date:	2002-05-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002

1KTD

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ...
Authors:	Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
Deposit date:	2002-01-15
Release date:	2002-05-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002

1K8I

CRYSTAL STRUCTURE OF MOUSE H2-DM
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain
Authors:	Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J.
Deposit date:	2001-10-24
Release date:	2001-12-05
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Crystal structure of mouse H2-M. Immunity, 9, 1998

6NK3

Crystal structure of murine Mxra8 ectodomain
Descriptor:	Matrix remodeling-associated protein 8
Authors:	Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-01-04
Release date:	2019-05-22
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, 177, 2019

6ORT

Crystal Structure of Bos taurus Mxra8 Ectodomain
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
Authors:	Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-04-30
Release date:	2020-03-04
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe, 27, 2020

5FFL

Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
Authors:	Nelson, C.A, Fremont, D.H.
Deposit date:	2015-12-18
Release date:	2016-08-31
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.602 Å)
Cite:	Discovery of a proteinaceous cellular receptor for a norovirus. Science, 353, 2016

6W37

STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
Descriptor:	ORF7a protein
Authors:	Nelson, C.A, Minasov, G, Shuvalova, L, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2020-03-09
Release date:	2020-04-29
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN To be published

1R0D

HIP1R THATCH DOMAIN CORE
Descriptor:	Huntingtin Interacting Protein 12
Authors:	Brett, T.J, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:	2003-09-19
Release date:	2004-07-06
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural definition of the F-actin-binding THATCH domain from HIP1R Nat.Struct.Mol.Biol., 13, 2006

1QTP

CRYSTAL STRUCTURE OF THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE
Descriptor:	AP-2 CLATHRIN ADAPTOR ALPHA SUBUNIT (ALPHA-ADAPTIN C)
Authors:	Traub, L.M, Downs, M.A, Westrich, J.L, Fremont, D.H.
Deposit date:	1999-06-28
Release date:	1999-07-12
Last modified:	2022-12-21
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Proc.Natl.Acad.Sci.USA, 96, 1999

8DAQ

CryoEM structure of Western equine encephalitis virus VLP
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2022-06-13
Release date:	2023-12-20
Method:	ELECTRON MICROSCOPY (4.35 Å)
Cite:	Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion To Be Published

8DAN

CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
Authors:	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2022-06-13
Release date:	2023-12-20
Method:	ELECTRON MICROSCOPY (4.74 Å)
Cite:	Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion To Be Published

6N08

Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2018-11-06
Release date:	2019-05-15
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.916 Å)
Cite:	Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2) to be published

6PLK

Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor:	Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:	Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-07-01
Release date:	2019-11-20
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J.Exp.Med., 217, 2020

6P6P

Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-06-04
Release date:	2020-07-01
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.31 Å)
Cite:	Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2) To Be Published

7SWW

SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2021-11-21
Release date:	2022-11-23
Last modified:	2023-02-01
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published

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