5T9D
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1MRQ
| Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone | Descriptor: | Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R. | Deposit date: | 2002-09-18 | Release date: | 2003-09-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. J.Mol.Biol., 331, 2003
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1Q5M
| Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin-E2 9-reductase, SULFATE ION | Authors: | Couture, J.F, Legrand, P, Cantin, L, Labrie, F, Luu-The, V, Breton, R. | Deposit date: | 2003-08-08 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Loop Relaxation, A Mechanism that Explains the Reduced Specificity of Rabbit 20alpha-Hydroxysteroid Dehydrogenase, A Member of the Aldo-Keto Reductase Superfamily. J.Mol.Biol., 339, 2004
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2H23
| Structure of Rubisco LSMT bound to Trimethyllysine and AdoHcy | Descriptor: | N-TRIMETHYLLYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-17 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
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2H2E
| Structure of Rubisco LSMT bound to AzaAdoMet and Lysine | Descriptor: | LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-18 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
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2H13
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2H21
| Structure of Rubisco LSMT bound to AdoMet | Descriptor: | Ribulose-1,5 bisphosphate carboxylase/oxygenase, S-ADENOSYLMETHIONINE | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-17 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
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2H2J
| Structure of Rubisco LSMT bound to Sinefungin and Monomethyllysine | Descriptor: | N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, SINEFUNGIN | Authors: | Couture, J.F, Hauk, G, Trievel, R.C. | Deposit date: | 2006-05-18 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases. J.Biol.Chem., 281, 2006
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2H14
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6O09
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6DVS
| Crystal structure of Pseudomonas stutzeri D-phenylglycine aminotransferase | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | Authors: | Couture, J.F, Chica, R. | Deposit date: | 2018-06-25 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase. Biochemistry, 57, 2018
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9C0O
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8SKJ
| Crystal structure of a Nanobody bound to the V5 peptide. | Descriptor: | NbA1, V5 Epitope Tag Peptide | Authors: | Zaghal, M, Matte, K, Venes, A, Patel, S, Laroche, G, Sarvan, S, Joshi, M, Couture, J.F, Giguere, P.M. | Deposit date: | 2023-04-19 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signaling. J.Biol.Chem., 299, 2023
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4O30
| Crystal structure of ATXR5 in complex with histone H3.1 and AdoHcy | Descriptor: | BETA-MERCAPTOETHANOL, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase ATXR6, ... | Authors: | Bergamin, E, Mongeon, V, Couture, J.F. | Deposit date: | 2013-12-17 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication. Science, 343, 2014
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6E2H
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7T7T
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7TLR
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7TLM
| Structure of Atopobium parvulum SufS | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Karunakaran, G, Couture, J.F. | Deposit date: | 2022-01-18 | Release date: | 2022-02-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease. Febs Lett., 596, 2022
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7TLP
| Structure of Atopobium parvulum SufS K235R | Descriptor: | Cysteine desulfurase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | Authors: | Karunakaran, G, Couture, J.F. | Deposit date: | 2022-01-18 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease. Febs Lett., 596, 2022
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7TLQ
| Structure of Atopobium parvulum SufS C375S | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Karunakaran, G, Couture, J.F. | Deposit date: | 2022-01-18 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease. Febs Lett., 596, 2022
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5VAC
| Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide | Descriptor: | DIMETHYL SULFOXIDE, Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, ... | Authors: | Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.F. | Deposit date: | 2017-03-24 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
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6D57
| Campylobacter jejuni ferric uptake regulator S1 metalated | Descriptor: | FORMIC ACID, Ferric uptake regulation protein, GLYCEROL, ... | Authors: | Sarvan, S, Brunzelle, J.S, Couture, J.F. | Deposit date: | 2018-04-19 | Release date: | 2018-05-23 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Functional insights into the interplay between DNA interaction and metal coordination in ferric uptake regulators. Sci Rep, 8, 2018
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6DK4
| Crystal structure of Campylobacter jejuni peroxide stress regulator | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ferric uptake regulation protein, MANGANESE (II) ION, ... | Authors: | Sarvan, S, Brunzelle, J.S, Couture, J.F. | Deposit date: | 2018-05-28 | Release date: | 2018-06-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structure of Campylobacter jejuni peroxide regulator. FEBS Lett., 592, 2018
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6E29
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6VHF
| Crystal structure of RbBP5 interacting domain of Cfp1 | Descriptor: | PHD-type domain-containing protein, ZINC ION | Authors: | Joshi, M, Couture, J.F. | Deposit date: | 2020-01-09 | Release date: | 2020-01-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.311 Å) | Cite: | A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS. Nucleic Acids Res., 48, 2020
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