2H13

Crystal structure of WDR5/histone H3 complex

Summary for 2H13

Related2H14
DescriptorWD-repeat protein 5, histone H3 lys-4 dimethylated (3 entities in total)
Functional Keywordshistone, beta-propeller, wd40-repeat, mll, transcription
Biological sourceHomo sapiens (human)
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Cellular locationNucleus  P61964
Total number of polymer chains2
Total molecular weight35884.74
Authors
Couture, J.F.,Collazo, E.,Trievel, R.C. (deposition date: 2006-05-15, release date: 2006-07-11, Last modification date: 2018-02-07)
Primary citation
Couture, J.F.,Collazo, E.,Trievel, R.C.
Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13:698-703, 2006
PubMed: 16829960 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1116
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.58 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2071101.9%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution