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6T9D
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BU of 6t9d by Molmil
Crystal structure of a bispecific DutaFab in complex with human VEGF121
Descriptor: VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A
Authors:Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
Deposit date:2019-10-28
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.905 Å)
Cite:DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
6T9E
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BU of 6t9e by Molmil
Crystal structure of a bispecific DutaFab in complex with human PDGF
Descriptor: DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B
Authors:Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
Deposit date:2019-10-28
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8C83
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BU of 8c83 by Molmil
Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-18
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
Authors:Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
5M5H
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BU of 5m5h by Molmil
RIBOSOME-BOUND YIDC INSERTASE
Descriptor: Membrane protein insertase YidC
Authors:Kedrov, A, Wickles, S, Crevenna, A.H, van der Sluis, E, Buschauer, R, Berninghausen, O, Lamb, D.C, Beckmann, R.
Deposit date:2016-10-21
Release date:2016-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural Dynamics of the YidC:Ribosome Complex during Membrane Protein Biogenesis.
Cell Rep, 17, 2016
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CBJ
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BU of 8cbj by Molmil
Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex
Descriptor: 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-25
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
4UTQ
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BU of 4utq by Molmil
A structural model of the active ribosome-bound membrane protein insertase YidC
Descriptor: ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC
Authors:Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R.
Deposit date:2014-07-22
Release date:2014-07-30
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8 Å)
Cite:A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc.
Elife, 3, 2014
4V7F
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BU of 4v7f by Molmil
Arx1 pre-60S particle.
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R.
Deposit date:2013-12-10
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
Nat Commun, 5, 2014
4V6W
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BU of 4v6w by Molmil
Structure of the D. melanogaster 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
4V5H
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BU of 4v5h by Molmil
E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide.
Descriptor: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Seidelt, B, Innis, C.A, Wilson, D.N, Gartmann, M, Armache, J, Villa, E, Trabuco, L.G, Becker, T, Mielke, T, Schulten, K, Steitz, T.A, Beckmann, R.
Deposit date:2009-10-26
Release date:2014-07-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
5MC6
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BU of 5mc6 by Molmil
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
Deposit date:2016-11-09
Release date:2017-01-18
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
6I7O
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BU of 6i7o by Molmil
The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2018-11-16
Release date:2019-01-16
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
4UY8
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BU of 4uy8 by Molmil
Molecular basis for the ribosome functioning as a L-tryptophan sensor - Cryo-EM structure of a TnaC stalled E.coli ribosome
Descriptor: 50S RIBOSOMAL PROTEIN L10, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ...
Authors:Bischoff, L, Berninghausen, O, Beckmann, R.
Deposit date:2014-08-29
Release date:2014-10-29
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular Basis for the Ribosome Functioning as an L-Tryptophan Sensor.
Cell Rep., 9, 2014
6EM5
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BU of 6em5 by Molmil
State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
4V7E
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BU of 4v7e by Molmil
Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ...
Authors:Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2013-11-22
Release date:2014-07-09
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
4URD
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BU of 4urd by Molmil
Cryo-EM map of Trigger Factor bound to a translating ribosome
Descriptor: TRIGGER FACTOR
Authors:Deeng, J, Chan, K.Y, van der Sluis, E, Bischoff, L, Berninghausen, O, Han, W, Gumbart, J, Schulten, K, Beatrix, B, Beckmann, R.
Deposit date:2014-06-27
Release date:2016-01-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Dynamic Behavior of Trigger Factor on the Ribosome.
J.Mol.Biol., 428, 2016
4V6U
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BU of 4v6u by Molmil
Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ...
Authors:Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N.
Deposit date:2012-08-09
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
Nucleic Acids Res., 41, 2013
4V6M
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BU of 4v6m by Molmil
Structure of the ribosome-SecYE complex in the membrane environment
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 16S RIBOSOMAL RNA, ...
Authors:Frauenfeld, J, Gumbart, J, van der Sluis, E.O, Funes, S, Gartmann, M, Beatrix, B, Mielke, T, Berninghausen, O, Becker, T, Schulten, K, Beckmann, R.
Deposit date:2011-02-08
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Cryo-EM structure of the ribosome-SecYE complex in the membrane environment.
Nat.Struct.Mol.Biol., 18, 2011
4V6X
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BU of 4v6x by Molmil
Structure of the human 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
1YSH
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BU of 1ysh by Molmil
Localization and dynamic behavior of ribosomal protein L30e
Descriptor: 40S RIBOSOMAL PROTEIN S13, RNA (101-MER), RNA (28-MER), ...
Authors:Halic, M, Becker, T, Frank, J, Spahn, C.M, Beckmann, R.
Deposit date:2005-02-08
Release date:2005-07-05
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Localization and dynamic behavior of ribosomal protein L30e
Nat.Struct.Mol.Biol., 12, 2005
7AJU
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BU of 7aju by Molmil
Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2020-09-29
Release date:2020-12-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
7AJT
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BU of 7ajt by Molmil
Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2020-09-29
Release date:2020-12-30
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
7AFT
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BU of 7aft by Molmil
Cryo-EM structure of the signal sequence-engaged post-translational Sec translocon
Descriptor: Mating factor alpha-1,Mating factor alpha-1, Protein translocation protein SEC63, Protein transport protein SBH1, ...
Authors:Weng, T.-H, Beatrix, B, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-09-20
Release date:2020-12-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the active post-translational Sec translocon.
Embo J., 40, 2021

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