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2IMD
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STRUCTURE OF SEMET 2-HYDROXYCHROMENE-2-CARBOXYLATE ISOMERASE (HCCA ISOMERASE)
Descriptor:2-hydroxychromene-2-carboxylate isomerase, PHOSPHATE ION, GLUTATHIONE, ...
Authors:Thompson, L.C., Ladner, J.E., Codreanu, S.G., Harp, J., Gilliland, G.L., Armstrong, R.N.
Deposit date:2006-10-04
Release date:2007-06-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:2-Hydroxychromene-2-carboxylic Acid Isomerase: A Kappa Class Glutathione Transferase from Pseudomonas putida
Biochemistry, 46, 2007
2IME
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2-HYDROXYCHROMENE-2-CARBOXYLATE ISOMERASE: A KAPPA CLASS GLUTATHIONE-S-TRANSFERASE FROM PSEUDOMONAS PUTIDA
Descriptor:2-hydroxychromene-2-carboxylate isomerase, PHOSPHATE ION, GLUTATHIONE, ...
Authors:Thompson, L.C., Ladner, J.E., Codreanu, S.G., Harp, J., Gilliland, G.L., Armstrong, R.N.
Deposit date:2006-10-04
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:2-Hydroxychromene-2-carboxylic Acid Isomerase: A Kappa Class Glutathione Transferase from Pseudomonas putida
Biochemistry, 46, 2007
2IMF
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2-HYDROXYCHROMENE-2-CARBOXYLATE ISOMERASE: A KAPPA CLASS GLUTATHIONE-S-TRANSFERASE FROM PSEUDOMONAS PUTIDA
Descriptor:2-hydroxychromene-2-carboxylate isomerase, PHOSPHATE ION, GLUTATHIONE, ...
Authors:Thompson, L.C., Ladner, J.E., Codreanu, S.G., Harp, J., Gilliland, G.L., Armstrong, R.N.
Deposit date:2006-10-04
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida.
Biochemistry, 46, 2007
3EUG
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
Descriptor:PROTEIN (GLYCOSYLASE), GLYCEROL
Authors:Xiao, G., Tordova, M., Jagadeesh, J., Drohat, A.C., Stivers, J.T., Gilliland, G.L.
Deposit date:1998-10-13
Release date:1999-10-13
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
3G6A
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CRYSTAL STRUCTURE OF ANTI-IL-13 ANTIBODY CNTO607
Descriptor:CNTO607 Fab Light chain, CNTO607 Fab Heavy chain
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2009-02-06
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.
J.Mol.Biol., 389, 2009
3G6D
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CNTO607 FAB AND IL-13
Descriptor:CNTO607 Fab Light chain, CNTO607 Fab Heavy chain, Interleukin-13, ...
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2009-02-06
Release date:2009-04-07
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.
J.Mol.Biol., 389, 2009
3I2C
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CRYSTAL STRUCTURE OF ANTI-IL-23 ANTIBODY CNTO4088
Descriptor:CNTO4088 LIGHT CHAIN, CNTO4088 HEAVY CHAIN, GLYCEROL
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2009-06-29
Release date:2009-07-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088.
Acta Crystallogr.,Sect.F, 66, 2010
3I84
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THE CRYSTAL STRUCTURE OF HUMAN EMMPRIN N-TERMINAL DOMAIN 1 IN P6(1)22 SPACE GROUP
Descriptor:Cervical EMMPRIN, CHLORIDE ION
Authors:Luo, J., Gilliland, G.L.
Deposit date:2009-07-09
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping.
Proteins, 77, 2009
3I85
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THE CRYSTAL STRUCTURE OF HUMAN EMMPRIN N-TERMINAL DOMAIN 1
Descriptor:Cervical EMMPRIN
Authors:Luo, J., Gilliland, G.L.
Deposit date:2009-07-09
Release date:2009-10-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping.
Proteins, 77, 2009
3IFD
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HUMAN SYNTHETIC MONOCYTE CHEMOATTRACTANT PROTEIN 1 (MCP-1)
Descriptor:C-C motif chemokine 2, POTASSIUM ION, PHOSPHATE ION
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2009-07-24
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis by native chemical ligation and crystal structure of human CCL2.
Biopolymers, 94, 2010
3MBX
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CRYSTAL STRUCTURE OF CHIMERIC ANTIBODY X836
Descriptor:X836 LIGHT CHAIN, X836 HEAVY CHAIN, SODIUM ION, ...
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2010-03-26
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:On the domain pairing in chimeric antibodies.
Mol.Immunol., 47, 2010
3MCK
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CRYSTAL STRUCTURE OF ANTI-BETA-AMYLOID ANTIBODY C705
Descriptor:C705 MONOCLONAL LIGHT CHAIN, C705 MONOCLONAL HEAVY CHAIN, ACETATE ION
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2010-03-29
Release date:2011-02-09
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antibody modeling assessment.
Proteins, 79, 2011
3MCL
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ANTI-BETA-AMYLOID ANTIBODY C706 FAB IN SPACE GROUP P21
Descriptor:C706 MONOCLONAL LIGHT CHAIN, C706 MONOCLONAL HEAVY CHAIN
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2010-03-29
Release date:2010-11-24
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:His-tag binding by antibody C706 mimics Beta-amyloid recognition.
J.Mol.Recognit., 24, 2010
3NAA
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CRYSTAL STRUCTURE OF FAB15 MUT5
Descriptor:Fab15 Mut5 light chain, Fab15 Mut5 heavy chain, ZINC ION, ...
Authors:Luo, J., Feng, Y., Gilliland, G.L.
Deposit date:2010-06-01
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
3NCJ
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CRYSTAL STRUCTURE OF FAB15 MUT8
Descriptor:Fab15 Mut8 light chain, Fab15 Mut8 heavy chain, ZINC ION, ...
Authors:Luo, J., Feng, Y., Gilliland, G.L.
Deposit date:2010-06-04
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
3NZH
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CRYSTAL STRUCTURE OF ANTI-EMMPRIN ANTIBODY 5F6 FAB
Descriptor:5F6 LIGHT CHAIN, 5F6 HEAVY CHAIN, GLYCEROL, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2010-07-16
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of anti-emmprin antibody 5F6 FAB
To be Published
3O11
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ANTI-BETA-AMYLOID ANTIBODY C706 FAB IN SPACE GROUP C2
Descriptor:C706 LIGHT CHAIN variable region, Ig kappa chain C region chimera, C706 HEAVY CHAIN variable region, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2010-07-20
Release date:2010-09-08
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:His-tag binding by antibody C706 mimics Beta-amyloid recognition.
J.Mol.Recognit., 2010
3QPQ
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CRYSTAL STRUCTURE OF ANTI-TLR3 ANTIBODY C1068 FAB
Descriptor:C1068 light chain, C1068 heavy chain, GLYCEROL, ...
Authors:Luo, J., Obmolova, G., Teplyakov, A., Gilliland, G.L.
Deposit date:2011-02-14
Release date:2011-08-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Fab C1068
To be Published
3QPX
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CRYSTAL STRUCTURE OF FAB C2507
Descriptor:Fab C2507 light chain, Fab C2507 heavy chain, SULFATE ION, ...
Authors:Luo, J., Teplyakov, A., Obmolova, O., Malia, T., Gilliland, G.L.
Deposit date:2011-02-14
Release date:2011-08-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Fab C2507
To be Published
3ULS
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CRYSTAL STRUCTURE OF FAB12
Descriptor:Fab12 light chain, Fab12 heavy chain
Authors:Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A.
Deposit date:2011-11-11
Release date:2012-05-23
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
3ULU
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STRUCTURE OF QUATERNARY COMPLEX OF HUMAN TLR3ECD WITH THREE FABS (FORM1)
Descriptor:Toll-like receptor 3, Fab15 light chain, Fab15 heavy chain, ...
Authors:Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A.
Deposit date:2011-11-11
Release date:2012-05-23
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
3ULV
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STRUCTURE OF QUATERNARY COMPLEX OF HUMAN TLR3ECD WITH THREE FABS (FORM2)
Descriptor:Toll-like receptor 3, Fab15 light chain, Fab15 heavy chain, ...
Authors:Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A.
Deposit date:2011-11-11
Release date:2012-05-23
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (3.522 Å)
Cite:Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
4EUG
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CRYSTALLOGRAPHIC AND ENZYMATIC STUDIES OF AN ACTIVE SITE VARIANT H187Q OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE: CRYSTAL STRUCTURES OF MUTANT H187Q AND ITS URACIL COMPLEX
Descriptor:PROTEIN (GLYCOSYLASE)
Authors:Xiao, G., Tordova, M., Drohat, A.C., Jagadeesh, J., Stivers, J.T., Gilliland, G.L.
Deposit date:1998-12-27
Release date:1999-07-23
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187.
Biochemistry, 38, 1999
4KMT
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY 5-51/O12
Descriptor:light chain O12/KAPPA, heavy chain 5-51/CNTO888/IGG1, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2013-05-08
Release date:2014-03-26
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4KQ3
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CRYSTAL STRUCTURE OF ANTI-IL-17A ANTIBODY CNTO3186
Descriptor:CNTO3186 light chain, CNTO3186 heavy chain, GLYCEROL, ...
Authors:Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
Deposit date:2013-05-14
Release date:2014-03-26
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural evidence for a constrained conformation of short CDR-L3 in antibodies.
Proteins, 82, 2014