5FWG

TETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE

Summary for 5FWG

DescriptorTETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE MU CLASS, (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE (3 entities in total)
Functional Keywordsglutathione transferase, unnatural amino acid, 5-fluorotryptophan, three-dimensional structure, transferase
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCytoplasm P04905
Total number of polymer chains2
Total molecular weight52784.62
Authors
Parsons, J.F.,Xiao, G.,Armstrong, R.N.,Gilliland, G.L. (deposition date: 1997-11-08, release date: 1999-01-27, Last modification date: 2017-11-29)
Primary citation
Parsons, J.F.,Xiao, G.,Gilliland, G.L.,Armstrong, R.N.
Enzymes harboring unnatural amino acids: mechanistic and structural analysis of the enhanced catalytic activity of a glutathione transferase containing 5-fluorotryptophan.
Biochemistry, 37:6286-6294, 1998
PubMed: 9572843 (PDB entries with the same primary citation)
DOI: 10.1021/bi980219e
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers472.1%23.1%11.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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