Author results

3L4J
  • Download 3l4j
  • View 3l4j
Molmil generated image of 3l4j
TOPOISOMERASE II-DNA CLEAVAGE COMPLEX, APO
分子名称:DNA topoisomerase 2, DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H., Burgin, A.B., Deweese, J.E., Osheroff, N., Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
3L4K
  • Download 3l4k
  • View 3l4k
Molmil generated image of 3l4k
TOPOISOMERASE II-DNA CLEAVAGE COMPLEX, METAL-BOUND
分子名称:DNA topoisomerase 2, DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H., Burgin, A.B., Deweese, J.E., Osheroff, N., Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
3NO0
  • Download 3no0
  • View 3no0
Molmil generated image of 3no0
AQUIFEX AEOLICUS TYPE IIA TOPOISOMERASE C-TERMINAL DOMAIN
分子名称:DNA gyrase subunit A, NITRATE ION, GLYCEROL
著者Tretter, E.M., Lerman, J.C., Berger, J.M.
登録日2010-06-24
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3004 Å)
主引用文献A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NUH
  • Download 3nuh
  • View 3nuh
Molmil generated image of 3nuh
A DOMAIN INSERTION IN E. COLI GYRB ADOPTS A NOVEL FOLD THAT PLAYS A CRITICAL ROLE IN GYRASE FUNCTION
分子名称:DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION
著者Schoeffler, A.J., May, A.P., Berger, J.M.
登録日2010-07-06
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.
Nucleic Acids Res., 38, 2010
3PEU
  • Download 3peu
  • View 3peu
Molmil generated image of 3peu
S. CEREVISIAE DBP5 L327V C-TERMINAL DOMAIN BOUND TO GLE1 H337R AND IP6
分子名称:ATP-dependent RNA helicase DBP5, Nucleoporin GLE1, SULFATE ION, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEV
  • Download 3pev
  • View 3pev
Molmil generated image of 3pev
S. CEREVISIAE DBP5 L327V C-TERMINAL DOMAIN BOUND TO GLE1 AND IP6
分子名称:ATP-dependent RNA helicase DBP5, Nucleoporin GLE1, SULFATE ION, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEW
  • Download 3pew
  • View 3pew
Molmil generated image of 3pew
S. CEREVISIAE DBP5 L327V BOUND TO RNA AND ADP BEF3
分子名称:ATP-dependent RNA helicase DBP5, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), ADENOSINE-5'-DIPHOSPHATE, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEY
  • Download 3pey
  • View 3pey
Molmil generated image of 3pey
S. CEREVISIAE DBP5 BOUND TO RNA AND ADP BEF3
分子名称:ATP-dependent RNA helicase DBP5, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), ADENOSINE-5'-DIPHOSPHATE, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3R8F
  • Download 3r8f
  • View 3r8f
Molmil generated image of 3r8f
REPLICATION INITIATOR DNAA BOUND TO AMPPCP AND SINGLE-STRANDED DNA
分子名称:Chromosomal replication initiator protein dnaA, 5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', MAGNESIUM ION, ...
著者Duderstadt, K.E., Chuang, K., Berger, J.M.
登録日2011-03-23
公開日2011-09-28
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (3.366 Å)
主引用文献DNA stretching by bacterial initiators promotes replication origin opening.
Nature, 478, 2011
3RRM
  • Download 3rrm
  • View 3rrm
Molmil generated image of 3rrm
S. CEREVISIAE DBP5 L327V BOUND TO NUP159, GLE1 H337R, IP6 AND ADP
分子名称:ATP-dependent RNA helicase DBP5, Nucleoporin GLE1, Nucleoporin NUP159, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2011-04-29
公開日2011-05-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3RRN
  • Download 3rrn
  • View 3rrn
Molmil generated image of 3rrn
S. CEREVISIAE DBP5 L327V BOUND TO GLE1 H337R AND IP6
分子名称:ATP-dependent RNA helicase DBP5, Nucleoporin GLE1, ADENOSINE-5'-DIPHOSPHATE, ...
著者Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
登録日2011-04-29
公開日2011-05-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (4.001 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3TO1
  • Download 3to1
  • View 3to1
Molmil generated image of 3to1
TWO SURFACES ON RTT106 MEDIATE HISTONE BINDING AND CHAPERONE ACTIVITY
分子名称:Histone chaperone RTT106
著者Zunder, R.M., Antczak, A.J., Berger, J.M., Rine, J.
登録日2011-09-02
公開日2011-12-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UC1
  • Download 3uc1
  • View 3uc1
Molmil generated image of 3uc1
MYCOBACTERIUM TUBERCULOSIS GYRASE TYPE IIA TOPOISOMERASE C-TERMINAL DOMAIN
分子名称:DNA gyrase subunit A, CALCIUM ION, ACETATE ION, ...
著者Tretter, E.M., Berger, J.M.
登録日2011-10-25
公開日2012-03-28
最終更新日2012-06-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs: II. THE SHAPE OF THE GyrA SUBUNIT C-TERMINAL DOMAIN (CTD) IS NOT A SOLE DETERMINANT FOR CONTROLLING SUPERCOILING EFFICIENCY.
J.Biol.Chem., 287, 2012
437D
  • Download 437d
  • View 437d
Molmil generated image of 437d
CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING
分子名称:RNA PSEUDOKNOT, MAGNESIUM ION, SODIUM ION
著者Su, L., Chen, L., Egli, M., Berger, J.M., Rich, A.
登録日1998-11-24
公開日1998-12-03
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
4E2K
  • Download 4e2k
  • View 4e2k
Molmil generated image of 4e2k
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN
分子名称:DNA primase, BENZAMIDINE
著者Rymer, R.U., Solorio, F.A., Clement, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-08
公開日2012-08-01
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDG
  • Download 4edg
  • View 4edg
Molmil generated image of 4edg
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO ATP AND MANGANESE
分子名称:DNA primase, BENZAMIDINE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDK
  • Download 4edk
  • View 4edk
Molmil generated image of 4edk
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO GTP AND MANGANESE
分子名称:DNA primase, BENZAMIDINE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDR
  • Download 4edr
  • View 4edr
Molmil generated image of 4edr
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO UTP AND MANGANESE
分子名称:DNA primase, BENZAMIDINE, URIDINE 5'-TRIPHOSPHATE, ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDT
  • Download 4edt
  • View 4edt
Molmil generated image of 4edt
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO PPGPP AND MANGANESE
分子名称:DNA primase, BENZAMIDINE, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDV
  • Download 4edv
  • View 4edv
Molmil generated image of 4edv
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO PPPGPP AND MANGANESE
分子名称:DNA primase, BENZAMIDINE, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate), ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EE1
  • Download 4ee1
  • View 4ee1
Molmil generated image of 4ee1
THE STRUCTURE OF THE S. AUREUS DNAG RNA POLYMERASE DOMAIN BOUND TO CTP AND MANGANESE
分子名称:DNA primase, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Rymer, R.U., Solorio, F.A., Chu, C., Corn, J.E., Wang, J.D., Berger, J.M.
登録日2012-03-28
公開日2012-07-25
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4FM9
  • Download 4fm9
  • View 4fm9
Molmil generated image of 4fm9
HUMAN TOPOISOMERASE II ALPHA BOUND TO DNA
分子名称:DNA topoisomerase 2-alpha, DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), ...
著者Wendorff, T.J., Schmidt, B.H., Heslop, P., Austin, C.A., Berger, J.M.
登録日2012-06-15
公開日2012-08-08
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage.
J.Mol.Biol., 424, 2012
4GFH
  • Download 4gfh
  • View 4gfh
Molmil generated image of 4gfh
TOPOISOMERASE II-DNA-AMPPNP COMPLEX
分子名称:DNA topoisomerase 2, DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H., Osheroff, N., Berger, J.M.
登録日2012-08-03
公開日2012-10-03
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (4.408 Å)
主引用文献Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity.
Nat.Struct.Mol.Biol., 19, 2012
4KM5
  • Download 4km5
  • View 4km5
Molmil generated image of 4km5
X-RAY CRYSTAL STRUCTURE OF HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS)
分子名称:Cyclic GMP-AMP synthase, ZINC ION
著者Kranzusch, P.J., Lee, A.S.Y., Berger, J.M., Doudna, J.A.
登録日2013-05-08
公開日2013-05-29
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
Cell Rep, 3, 2013
4MN4
  • Download 4mn4
  • View 4mn4
Molmil generated image of 4mn4
STRUCTURAL BASIS FOR THE MUKB-TOPOISOMERASE IV INTERACTION
分子名称:DNA topoisomerase 4 subunit A, Chromosome partition protein MukB
著者Vos, S.M., Stewart, N.K., Oakley, M.G., Berger, J.M.
登録日2013-09-09
公開日2013-10-23
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo.
Embo J., 32, 2013