Author results

6FI7
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E.COLI SIGMA FACTOR S (RPOS) REGION 4
Descriptor:RNA polymerase sigma factor RpoS
Authors:Liu, B., Matthews, S.J.
Deposit date:2018-01-17
Release date:2018-06-06
Last modified:2018-06-13
Method:SOLUTION NMR
Cite:T7 phage factor required for managing RpoS inEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2WNM
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SOLUTION STRUCTURE OF GP2
Descriptor:GENE 2
Authors:Camara, B., Liu, M., Shadrinc, A., Liu, B., Simpson, P., Weinzierl, R., Severinovc, K., Cota, E., Matthews, S., Wigneshweraraj, S.R.
Deposit date:2009-07-13
Release date:2010-02-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:T7 Phage Protein Gp2 Inhibits the Escherichia Coli RNA Polymerase by Antagonizing Stable DNA Strand Separation Near the Transcription Start Site.
Proc.Natl.Acad.Sci.USA, 107, 2010
3UAF
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CRYSTAL STRUCTURE OF A TTR-52 MUTANT OF C. ELEGANS
Descriptor:TTR-52
Authors:Kang, Y.Y., Zhao, D.F., Liang, H.H., Liu, B., Liu, Q.W., Wang, X.C., Liu, Y.F.
Deposit date:2011-10-21
Release date:2012-10-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural study of TTR-52 reveals the mechanism by which a bridging molecule mediates apoptotic cell engulfment
Genes Dev., 26, 2012
4F1Z
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CRYSTAL STRUCTURES REVEAL THE MULTI-LIGAND BINDING MECHANISM OF THE STAPHYLOCOCCUS AUREUS CLFB
Descriptor:Clumping factor B, peptide from Keratin, type I cytoskeletal 10, ...
Authors:Yang, M.J., Xiang, H., Wang, J.W., Liu, B., Chen, Y.G., Liu, L., Deng, X.M., Feng, Y.
Deposit date:2012-05-07
Release date:2012-08-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
4F20
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CRYSTAL STRUCTURES REVEAL THE MULTI-LIGAND BINDING MECHANISM OF THE STAPHYLOCOCCUS AUREUS CLFB
Descriptor:Clumping factor B, peptide from Dermokine, MAGNESIUM ION
Authors:Yang, M.J., Xiang, H., Wang, J.W., Liu, B., Chen, Y.G., Liu, L., Deng, X.M., Feng, Y.
Deposit date:2012-05-07
Release date:2012-08-08
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
4F24
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CRYSTAL STRUCTURES REVEAL THE MULTI-LIGAND BINDING MECHANISM OF THE STAPHYLOCOCCUS AUREUS CLFB
Descriptor:Clumping factor B, MAGNESIUM ION
Authors:Yang, M.J., Xiang, H., Wang, J.W., Liu, B., Chen, Y.G., Liu, L., Deng, X.M., Feng, Y.
Deposit date:2012-05-07
Release date:2012-08-08
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
4F27
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CRYSTAL STRUCTURES REVEAL THE MULTI-LIGAND BINDING MECHANISM OF THE STAPHYLOCOCCUS AUREUS CLFB
Descriptor:Clumping factor B, peptide from Fibrinogen alpha chain, MAGNESIUM ION
Authors:Yang, M.J., Xiang, H., Wang, J.W., Liu, B., Chen, Y.G., Liu, L., Deng, X.M., Feng, Y.
Deposit date:2012-05-07
Release date:2012-08-08
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.917 Å)
Cite:Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
4XZ8
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THE CRYSTAL STRUCTURE OF ERVE VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Guo, Y., Wang, W., Liu, X., Wang, X., Wang, J., Huo, T., Liu, B.
Deposit date:2015-02-04
Release date:2015-09-02
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins.
J.Virol., 89, 2015
4XZA
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THE CRYSTAL STRUCTURE OF ERVE VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Guo, Y., Wang, W., Liu, X., Wang, X., Wang, J., Huo, T., Liu, B.
Deposit date:2015-02-04
Release date:2015-09-02
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins.
J.Virol., 89, 2015
4XZC
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THE CRYSTAL STRUCTURE OF KUPE VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Guo, Y., Wang, W., Liu, X., Wang, X., Wang, J., Huo, T., Liu, B.
Deposit date:2015-02-04
Release date:2015-09-02
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins.
J.Virol., 89, 2015
4XZE
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THE CRYSTAL STRUCTURE OF HAZARA VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Guo, Y., Wang, W., Liu, X., Wang, X., Wang, J., Huo, T., Liu, B.
Deposit date:2015-02-04
Release date:2015-09-02
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins.
J.Virol., 89, 2015
5H4D
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CRYSTAL STRUCTURE OF HSIRT3 IN COMPLEX WITH A SPECIFIC AGONIST AMIODARONE HYDROCHLORIDE
Descriptor:NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ARG-HIS-LYS, ...
Authors:Zhang, S., Fu, L., Liu, J., Liu, B.
Deposit date:2016-10-31
Release date:2017-11-08
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride
To Be Published
5TDH
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THE CRYSTAL STRUCTURE OF THE DOMINANT NEGATIVE MUTANT G PROTEIN ALPHA(I)-1-BETA-1-GAMMA-2 G203A/A326S
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Liu, P., Jia, M.-Z., Zhou, X.E., de Waal, P.W., Dickson, B.M., Liu, B., Hou, L., Yin, Y.-T., Kang, Y.-Y., Shi, Y., Melcher, K., Xu, H.E., Jiang, Y.
Deposit date:2016-09-19
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Acta Pharmacol.Sin., 37, 2016
5V54
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CRYSTAL STRUCTURE OF 5-HT1B RECEPTOR IN COMPLEX WITH METHIOTHEPIN
Descriptor:5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B, 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine
Authors:Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.
Deposit date:2017-03-13
Release date:2018-02-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
1HVS
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STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING
Descriptor:HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE
Authors:Baldwin, E.T., Bhat, T.N., Liu, B., Pattabiraman, N., Erickson, J.W.
Deposit date:1994-11-17
Release date:1995-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase.
Nat.Struct.Biol., 2, 1995
1APL
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CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS
Descriptor:DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN)
Authors:Wolberger, C., Vershon, A.K., Liu, B., Johnson, A.D., Pabo, C.O.
Deposit date:1993-10-04
Release date:1993-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
1HDD
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CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS
Descriptor:DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*C P*CP*TP*AP*A)-3'), DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN)
Authors:Kissinger, C.R., Liu, B., Martin-Blanco, E., Kornberg, T.B., Pabo, C.O.
Deposit date:1991-09-16
Release date:1992-01-15
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 63, 1990
1STR
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STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE AC-CHPQNT-NH2 DIMER
Descriptor:STREPTAVIDIN, AC-CHPQNT-NH2
Authors:Katz, B.A., Cass, R.T., Liu, B., Arze, R., Collins, N.
Deposit date:1995-09-12
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
1STS
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STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE FCHPQNT-NH2 DIMER
Descriptor:STREPTAVIDIN, FCHPQNT-NH2
Authors:Katz, B.A., Cass, R.T., Liu, B., Arze, R., Collins, N.
Deposit date:1995-09-12
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
1YUK
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THE CRYSTAL STRUCTURE OF THE PSI/HYBRID DOMAIN/ I-EGF1 SEGMENT FROM THE HUMAN INTEGRIN BETA2 AT 1.8 RESOLUTION
Descriptor:Integrin beta-2 A chain, Integrin beta-2 B chain, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Shi, M., Sundramurthy, K., Liu, B., Tan, S.M., Law, S.K., Lescar, J.
Deposit date:2005-02-14
Release date:2005-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution
J.Biol.Chem., 280, 2005
2MPV
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STRUCTURAL INSIGHT INTO HOST RECOGNITION AND BIOFILM FORMATION BY AGGREGATIVE ADHERENCE FIMBRIAE OF ENTEROAGGREGATIVE ESHERICHIA COLI
Descriptor:Major fimbrial subunit of aggregative adherence fimbria II AafA
Authors:Matthews, S.J., Yang, Y., Berry, A.A., Pakharukova, N., Garnett, J.A., Lee, W., Cota, E., Liu, B., Roy, S., Tuittila, M., Marchant, J., Inman, K.G., Ruiz-Perez, F., Mandomando, I., Nataro, J.P., Zavialov, A.V.
Deposit date:2014-06-04
Release date:2014-10-29
Method:SOLUTION NMR
Cite:Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
3OMV
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CRYSTAL STRUCTURE OF C-RAF (RAF-1)
Descriptor:RAF proto-oncogene serine/threonine-protein kinase, (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
Authors:Hatzivassiliou, G., Song, K., Yen, I., Brandhuber, B.J., Anderson, D.J., Alvarado, R., Ludlam, M.J., Stokoe, D., Gloor, S.L., Vigers, G.P.A., Morales, T., Aliagas, I., Liu, B., Sideris, S., Hoeflich, K.P., Jaiswal, B.S., Seshagiri, S., Koeppen, H., Belvin, M., Friedman, L.S., Malek, S.
Deposit date:2010-08-27
Release date:2010-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Nature, 464, 2010
4R05
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CRYSTAL STRUCTURE OF THE REFOLDED DENV3 METHYLTRANSFERASE
Descriptor:Nonstructural protein NS5
Authors:Brecher, M.B., Li, Z., Zhang, J., Chen, H., Lin, Q., Liu, B., Li, H.M.
Deposit date:2014-07-29
Release date:2014-11-12
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24, 2015
6F24
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PH DOMAIN FROM PFAPH
Descriptor:C-terminal PH domain from PfAPH
Authors:Darvill, N., Liu, B., Matthews, S., Soldati-Favre, D., Rouse, S., Benjamin, S., Blake, T., Dubois, D.J., Hammoudi, P.M., Pino, P.
Deposit date:2017-11-23
Release date:2018-12-12
Method:SOLUTION NMR
Cite:C-terminal PH domain from P. falciparum acylated plekstrin homology domain containing protein (APH)
To Be Published
6F8E
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PH DOMAIN FROM TGAPH
Descriptor:Pleckstrin homology domain
Authors:Darvill, N., Liu, B., Matthews, S., Soldati-Favre, D., Rouse, S., Benjamin, S., Blake, T., Dubois, D.J., Hammoudi, P.M., Pino, P.
Deposit date:2017-12-13
Release date:2019-01-30
Method:SOLUTION NMR
Cite:Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.
Structure, 26, 2018