Author results

1IAY
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CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH COFACTOR PLP AND INHIBITOR AVG
Descriptor:1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, PYRIDOXAL-5'-PHOSPHATE, 2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID
Authors:Huai, Q., Xia, Y., Chen, Y., Callahan, B., Li, N., Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001
2AXE
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IODINATED COMPLEX OF ACETYL XYLAN ESTERASE AT 1.80 ANGSTROMS
Descriptor:ACETYL XYLAN ESTERASE, SULFATE ION
Authors:Ghosh, D., Erman, M., Sawicki, M.W., Lala, P., Weeks, D.R., Li, N., Pangborn, W., Thiel, D.J., Jornvall, H., Eyzaguirre, J.
Deposit date:1998-09-01
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase.
Acta Crystallogr.,Sect.D, 55, 1999
3O72
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CRYSTAL STRUCTURE OF EFEB IN COMPLEX WITH HEME
Descriptor:Redox component of a tripartite ferrous iron transporter, PROTOPORPHYRIN IX CONTAINING FE, OXYGEN MOLECULE
Authors:Liu, X., Du, Q., Wang, Z., Zhu, D., Huang, Y., Li, N., Xu, S., Gu, L.
Deposit date:2010-07-30
Release date:2011-03-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: ASP235 plays divergent roles in different enzyme-catalyzed processes
J.Biol.Chem., 286, 2011
3TB4
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CRYSTAL STRUCTURE OF THE ISC DOMAIN OF VIBB
Descriptor:Vibriobactin-specific isochorismatase, B-OCTYLGLUCOSIDE, TRIETHYLENE GLYCOL, ...
Authors:Liu, S., Zhang, C., Niu, B., Li, N., Liu, M., Wei, T., Zhu, D., Xu, S., Gu, L.
Deposit date:2011-08-05
Release date:2012-08-29
Last modified:2014-01-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
Acta Crystallogr.,Sect.D, 68, 2012
3TEF
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CRYSTAL STRUCTURE OF THE PERIPLASMIC CATECHOLATE-SIDEROPHORE BINDING PROTEIN VCTP FROM VIBRIO CHOLERAE
Descriptor:Iron(III) ABC transporter, periplasmic iron-compound-binding protein
Authors:Liu, X., Wang, Z., Liu, S., Li, N., Chen, Y., Zhu, C., Zhu, D., Wei, T., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-08-13
Release date:2012-08-15
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7 A resolution
Febs Lett., 586, 2012
3TG2
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CRYSTAL STRUCTURE OF THE ISC DOMAIN OF VIBB IN COMPLEX WITH ISOCHORISMATE
Descriptor:Vibriobactin-specific isochorismatase, (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, TRIETHYLENE GLYCOL
Authors:Liu, S., Zhang, C., Niu, B., Li, N., Liu, X., Liu, M., Wei, T., Zhu, D., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-08-17
Release date:2012-08-29
Last modified:2014-01-01
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
Acta Crystallogr.,Sect.D, 68, 2012
4EQ8
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CRYSTAL STRUCTURE OF PA1844 FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Putative uncharacterized protein, GLYCEROL
Authors:Shang, G., Li, N., Zhang, J., Lu, D., Yu, Q., Zhao, Y., Liu, X., Xu, S., Gu, L.
Deposit date:2012-04-18
Release date:2012-09-12
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.392 Å)
Cite:Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4EQA
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CRYSTAL STRUCTURE OF PA1844 IN COMPLEX WITH PA1845 FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Putative uncharacterized protein
Authors:Shang, G., Li, N., Zhang, J., Lu, D., Yu, Q., Zhao, Y., Liu, X., Xu, S., Gu, L.
Deposit date:2012-04-18
Release date:2012-09-12
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4F5W
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CRYSTAL STRUCTURE OF LIGAND FREE HUMAN STING CTD
Descriptor:Transmembrane protein 173, CALCIUM ION
Authors:Gu, L., Shang, G., Zhu, D., Li, N., Zhang, J., Zhu, C., Lu, D., Liu, C., Yu, Q., Zhao, Y., Xu, S.
Deposit date:2012-05-13
Release date:2012-06-27
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
4F5Y
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CRYSTAL STRUCTURE OF HUMAN STING CTD COMPLEX WITH C-DI-GMP
Descriptor:Transmembrane protein 173, CALCIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Gu, L., Shang, G., Zhu, D., Li, N., Zhang, J., Zhu, C., Lu, D., Liu, C., Yu, Q., Zhao, Y., Xu, S.
Deposit date:2012-05-13
Release date:2012-06-27
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
4LA4
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CRYSTAL STRUCTURE OF NATIVE PNPB
Descriptor:NAD(P)H dehydrogenase (quinone)
Authors:Su, J., Zhang, C., Li, N., Gu, L.
Deposit date:2013-06-19
Release date:2014-06-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of native PnpB
To be Published
4LAF
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CRYSTAL STRUCTURE OF PNPB COMPLEX WITH FMN
Descriptor:NAD(P)H dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE
Authors:Su, J., Zhang, C., Li, N., Gu, L.
Deposit date:2013-06-19
Release date:2014-06-25
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:Crystal structure of PnpB complex with FMN
To be Published
5HH9
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STRUCTURE OF PVDN FROM PSEUDOMONAS AERUGINOSA
Descriptor:PvdN, PYRIDOXAL-5'-PHOSPHATE
Authors:Xia, H., Bai, G., Liu, S., Li, N., Xu, S., Chen, K., Yao, Q., Gu, L.
Deposit date:2016-01-10
Release date:2017-01-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural and Biochemical Characterization of a Novel L-Cystine Desulfurase involved in the biosynthesis of the major siderophore pyoverdine in Pseudomonas aeruginosa
To Be Published
5B73
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CRYSTAL STRUCTURE OF HUMAN ZMYND8 PHD-BROMO-PWWP DOMAIN
Descriptor:Protein kinase C-binding protein 1, ZINC ION
Authors:Li, H., Li, Y., Zheng, X.
Deposit date:2016-06-03
Release date:2016-11-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes
Mol.Cell, 63, 2016
4RAX
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A REGULATORY DOMAIN OF AN ION CHANNEL
Descriptor:Piezo-type mechanosensitive ion channel component 1
Authors:Ge, J., Yang, M.
Deposit date:2014-09-11
Release date:2015-09-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Architecture of the mammalian mechanosensitive Piezo1 channel.
Nature, 527, 2015
4MKC
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CRYSTAL STRUCTURE OF ANAPLASTIC LYMPHOMA KINASE COMPLEXED WITH LDK378
Descriptor:ALK tyrosine kinase receptor, GLYCEROL, 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine
Authors:Lee, C.C., Spraggon, G.
Deposit date:2013-09-04
Release date:2014-04-09
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Cancer Discov, 4, 2014
5DP3
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP4
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 3
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP5
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 4
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP6
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 7
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP7
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 5
Descriptor:3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP8
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 8
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DP9
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 9
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
5DPA
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 6
Descriptor:3C proteinase, ethyl (2Z,4S)-4-[(N-acetyl-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
4ES4
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CRYSTAL STRUCTURE OF YDIV AND FLHD COMPLEX
Descriptor:Putative cyclic di-GMP regulator CdgR, Flagellar transcriptional regulator FlhD
Authors:Li, B., Gu, L.
Deposit date:2012-04-22
Release date:2012-10-10
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012