Author results

3DXN
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CRYSTAL STRUCTURE OF THE CALCIUM-DEPENDENT KINASE FROM TOXOPLASMA GONDII, 541.M00134, KINASE DOMAIN.
Descriptor:Calmodulin-like domain protein kinase isoform 3
Authors:Wernimont, A.K., Lew, J., Kozieradzki, I., Cossar, D., Wasney, G., Lin, Y.H., Hassani, A., Ali, A., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Wikstrom, M., Edwards, A.M., Hui, R., Artz, J.D., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structure of the calcium-dependent kinase from toxoplasma gondii, 541.m00134, kinase domain.
To be Published
3DYD
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HUMAN TYROSINE AMINOTRANSFERASE
Descriptor:Tyrosine aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-07-27
Release date:2008-08-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human Tyrosine Aminotransferase
To be Published
3DZ8
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CRYSTAL STRUCTURE OF HUMAN RAB3B GTPASE BOUND WITH GDP
Descriptor:Ras-related protein Rab-3B, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Shen, Y., Tong, Y., Sukumar, D., Tempel, W., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Wilkstrom, M., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-07-29
Release date:2008-08-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human Rab3B GTPase bound with GDP
To be Published
3DZQ
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HUMAN EPHA3 KINASE DOMAIN IN COMPLEX WITH INHIBITOR AWL-II-38.3
Descriptor:EPH receptor A3, N-[2-methyl-5-({[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide
Authors:Walker, J.R., Syeda, F., Gray, N., Mansoor, W., Mackenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-07-30
Release date:2008-08-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Kinase Domain of Human Ephrin Type-A Receptor 3 (Epha3) in Complex with ALW-II-38-3.
To be Published
3E6Q
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PUTATIVE 5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE FROM PSEUDOMONAS AERUGINOSA.
Descriptor:putative 5-carboxymethyl-2-hydroxymuconate isomerase, 1,2-ETHANEDIOL, FORMIC ACID, ...
Authors:Osipiuk, j., Xu, x., Cui, h., Savchenko, a., Edwards, a.m., Joachimiak, a., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-08-15
Release date:2008-08-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:X-ray crystal structure of putative 5-carboxymethyl-2-hydroxymuconate isomerase from Pseudomonas aeruginosa.
To be Published
3E77
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HUMAN PHOSPHOSERINE AMINOTRANSFERASE IN COMPLEX WITH PLP
Descriptor:Phosphoserine aminotransferase, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL
Authors:Lehtio, L., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, S.G., Tresaugues, L., Van Den Berg, S., Welin, M., Wikstrom, M., Wisniewska, M., Weigelt, J., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-08-18
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human phosphoserine aminotransferase in complex with PLP
TO BE PUBLISHED
3E7V
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CRYSTAL STRUCTURE OF HUMAN HASPIN WITH A PYRAZOLO-PYRIMIDINE LIGAND
Descriptor:Serine/threonine-protein kinase haspin, 3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine, NICKEL (II) ION, ...
Authors:Filippakopoulos, P., Eswaran, J., Keates, T., Burgess-Brown, N., Fedorov, O., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wickstroem, M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2008-08-19
Release date:2008-10-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand
To be Published
3E8X
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PUTATIVE NAD-DEPENDENT EPIMERASE/DEHYDRATASE FROM BACILLUS HALODURANS.
Descriptor:Putative NAD-dependent epimerase/dehydratase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CHLORIDE ION
Authors:Osipiuk, J., Skarina, T., Onopriyenko, O., Savchenko, A., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-08-20
Release date:2008-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of putative NAD-dependent epimerase/dehydratase from Bacillus halodurans.
To be Published
3E95
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CRYSTAL STRUCTURE OF THE PLASMODIUM FALCIPARUM UBIQUITIN CONJUGATING ENZYME COMPLEX, PFUBC13-PFUEV1A
Descriptor:Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2, UNKNOWN ATOM OR ION
Authors:Wernimont, A.K., Lam, A., Ali, A., Brokx, S., Lin, Y.H., Zhao, Y., Lew, J., Ravichandran, M., Wasney, G., Vedadi, M., Kozieradzki, I., Schapira, M., Bochkarev, A., Wilkstrom, M., BOuntra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Qiu, W., Brand, V.B., Structural Genomics Consortium (SGC)
Deposit date:2008-08-21
Release date:2008-09-30
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a
TO BE PUBLISHED
3EAP
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CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF ARHGAP11A
Descriptor:Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION
Authors:Shen, Y., Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2008-08-26
Release date:2008-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
3EB0
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CRYSTAL STRUCTURE OF CGD4_240 FROM CRYPTOSPORIDIUM PARVUM IN COMPLEX WITH INDIRUBIN E804
Descriptor:Putative uncharacterized protein, 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one, GLYCEROL
Authors:Wernimont, A.K., Fedorov, O., Lam, A., Ali, A., Zhao, Y., Lew, J., Wasney, G., Vedadi, M., Kozieradzki, I., Schapira, M., Bochkarev, A., Wilstrom, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Lin, Y.H., Structural Genomics Consortium (SGC)
Deposit date:2008-08-26
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804
TO BE PUBLISHED
3EBQ
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CRYSTAL STRUCTURE OF HUMAN PPPDE1
Descriptor:MOLECULE: PPPDE1 (PERMUTED PAPAIN FOLD PEPTIDASES OF DSRNA VIRUSES AND EUKARYOTES 1), UPF0326 protein FAM152B, MERCURY (II) ION
Authors:Walker, J.R., Akutsu, M., Qiu, L., Li, Y., Slessarev, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-08-28
Release date:2008-11-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Human PPPDE1
To be Published
3EC8
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THE CRYSTAL STRUCTURE OF THE RA DOMAIN OF FLJ10324 (RADIL)
Descriptor:Putative uncharacterized protein FLJ10324, CHLORIDE ION, LEAD (II) ION, ...
Authors:Wisniewska, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Berglund, H., Structural Genomics Consortium (SGC)
Deposit date:2008-08-29
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the RA domain of FLJ10324 (RADIL)
to be published
3ECI
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MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 ALPHA ISOFORM A (MAP1ALC3)
Descriptor:Microtubule-associated protein 1 light chain 3 alpha
Authors:Walker, J.R., Davis, T.L., Mujib, S., Butler-Cole, C., Tempel, W., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Dhe-Paganon, S.
Deposit date:2008-08-30
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Human Autophagy-Related Protein LC3 A
To be Published
3EDT
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CRYSTAL STRUCTURE OF THE MUTATED S328N HKLC2 TPR DOMAIN
Descriptor:Kinesin light chain 2, UNKNOWN ATOM OR ION
Authors:Zhu, H., Shen, Y., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-03
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of mutated S328N TPR domain of human kinesin light chain 2
To be published
3ELB
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HUMAN CTP: PHOSPHOETHANOLAMINE CYTIDYLYLTRANSFERASE IN COMPLEX WITH CMP
Descriptor:Ethanolamine-phosphate cytidylyltransferase, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL
Authors:Karlberg, T., Welin, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-22
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human CTP:Phosphoethanolamine Cytidylyltransferase
To be Published
3EO2
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CRYSTAL STRUCTURE OF THE RHOGEF DOMAIN OF HUMAN NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN
Descriptor:Neuroepithelial cell-transforming gene 1 protein, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-26
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein
To be Published
3EPP
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CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE (RNMT) IN COMPLEX WITH SINEFUNGIN
Descriptor:mRNA cap guanine-N7 methyltransferase, SINEFUNGIN
Authors:Amaya, M.F., Zeng, H., Loppnau, P., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Min, J., Plotnikov, A.N., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-29
Release date:2008-10-21
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin.
To be Published
3EPY
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA BINDING DOMAIN 7 COMPLEXED WITH PALMITOYL-COA
Descriptor:Acyl-CoA-binding domain-containing protein 7, COENZYME A, PALMITIC ACID
Authors:Kavanagh, K.L., Salah, E., Yue, W.W., Savitsky, P., Murray, J.W., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2008-09-30
Release date:2009-01-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Crystal Structure of human acyl-CoA binding domain 7 complexed with palmitoyl-Coa
To be Published
3EQ5
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CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN
Descriptor:Ski-like protein
Authors:Tresaugues, L., Wisniewska, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Van Den Berg, S., Welin, M., Wikstrom, M., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-09-30
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of fragment 137 to 238 of the human Ski-like protein.
To be Published
3EXC
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STRUCTURE OF THE RNA'SE SSO8090 FROM SULFOLOBUS SOLFATARICUS
Descriptor:Uncharacterized protein, CHLORIDE ION, SODIUM ION
Authors:Singer, A.U., Skarina, T., Tan, K., Kagan, O., Onopriyenko, O., Edwards, A.M., Joachimiak, A., Yakunin, A.F., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-10-16
Release date:2008-11-11
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the RNA'se SSO8090 from Sulfolobus solfataricus
To be Published
3EXM
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CRYSTAL STRUCTURE OF THE PHOSPHATASE SC4828 WITH THE NON-HYDROLYZABLE NUCLEOTIDE GPCP
Descriptor:Phosphatase SC4828, CALCIUM ION, SODIUM ION, ...
Authors:Singer, A.U., Xu, X., Zheng, H., Joachimiak, A., Edwards, A.M., Savchenko, A., Yakunin, A.F., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of a new family of prokaryotic nucleoside diphosphatases.
To be Published
3EZ3
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CRYSTAL STRUCTURE OF PLASMODIUM VIVAX GERANYLGERANYLPYROPHOSPHATE SYNTHASE PVX_092040 WITH ZOLEDRONATE AND IPP BOUND
Descriptor:Farnesyl pyrophosphate synthase, putative, ZOLEDRONIC ACID, ...
Authors:Wernimont, A.K., Lew, J., Zhao, Y., Kozieradzki, I., Cossar, D., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Artz, J.D., Structural Genomics Consortium (SGC)
Deposit date:2008-10-22
Release date:2008-12-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound
TO BE PUBLISHED
3F0N
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MUS MUSCULUS MEVALONATE PYROPHOSPHATE DECARBOXYLASE
Descriptor:MEVALONATE PYROPHOSPHATE DECARBOXYLASE, PHOSPHATE ION
Authors:Walker, J.R., Davis, T., Vesterberg, A., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-10-25
Release date:2008-11-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Mus Musculus Mevalonate Pyrophosphate Decarboxylase
To be Published
3F0W
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HUMAN NUMB-LIKE PROTEIN, PHOSPHOTYROSINE INTERACTION DOMAIN
Descriptor:Numb-like protein, SULFATE ION, CHLORIDE ION
Authors:Lehtio, L., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., D Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-10-27
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human NUMB-like protein, phosphotyrosine interaction domain
To be Published