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6VP0
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BU of 6vp0 by Molmil
Human Diacylglycerol Acyltransferase 1 in complex with oleoyl-CoA
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Diacylglycerol O-acyltransferase 1, Lauryl Maltose Neopentyl Glycol, ...
Authors:Wang, L, Qian, H, Han, Y, Nian, Y, Ren, Z, Zhang, H, Hu, L, Prasad, B.V.V, Yan, N, Zhou, M.
Deposit date:2020-02-01
Release date:2020-05-13
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and mechanism of human diacylglycerol O-acyltransferase 1.
Nature, 581, 2020
6PE0
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BU of 6pe0 by Molmil
Msp1 (E214Q)-substrate complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Membrane-spanning ATPase-like protein, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
6PDY
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BU of 6pdy by Molmil
Msp1-substrate complex in open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
2LKT
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BU of 2lkt by Molmil
Solution structure of N-terminal domain of human TIG3 in 2 M UREA
Descriptor: Retinoic acid receptor responder protein 3
Authors:Wang, L, Yu, W, Xia, B.
Deposit date:2011-10-21
Release date:2012-10-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:(1)H, (13)C, and (15)N resonance assignments of the N-terminal domain of human TIG3
Biomol.Nmr Assign., 6, 2012
4Y7N
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BU of 4y7n by Molmil
The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation.
Descriptor: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, L, Chong, J, Wang, D.
Deposit date:2015-02-15
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
4Y52
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BU of 4y52 by Molmil
Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation.
Descriptor: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, L, Chong, J, Wang, D.
Deposit date:2015-02-11
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
6FXD
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BU of 6fxd by Molmil
Crystal structure of MupZ from Pseudomonas fluorescens
Descriptor: MupZ
Authors:Wang, L, Parnell, A, Williams, C, Bakar, N.A, van der Kamp, M.W, Simpson, T.J, Race, P.R, Crump, M.P, Willis, C.L.
Deposit date:2018-03-08
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis
Nat Catal, 2018
3Q4A
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BU of 3q4a by Molmil
Crystal structure of the TPR domain of CHIP complexed with phosphorylated Smad1 peptide
Descriptor: STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L, Chen, L, Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.542 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
1BLR
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BU of 1blr by Molmil
NMR SOLUTION STRUCTURE OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II, 22 STRUCTURES
Descriptor: CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II
Authors:Wang, L, Li, Y, Abilddard, F, Yan, H, Markely, J.
Deposit date:1998-07-20
Release date:1999-01-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry, 37, 1998
3Q47
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BU of 3q47 by Molmil
Crystal structure of TPR domain of CHIP complexed with pseudophosphorylated Smad1 peptide
Descriptor: STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L, Chen, L, Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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BU of 3q49 by Molmil
Crystal structure of the TPR domain of CHIP complexed with Hsp70-C peptide
Descriptor: Hsp70-C peptide, STIP1 homology and U box-containing protein 1
Authors:Wang, L, Chen, L, Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
6PDW
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BU of 6pdw by Molmil
Msp1-substrate complex in closed conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
7YR4
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BU of 7yr4 by Molmil
SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(interface)
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:BA.2.75 in complex with ACE2
To Be Published
7U4T
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BU of 7u4t by Molmil
Human V-ATPase in state 2 with SidK and mEAK-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ...
Authors:Wang, L, Fu, T.M.
Deposit date:2022-03-01
Release date:2022-08-24
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UPT
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BU of 7upt by Molmil
Human mitochondrial AAA protein ATAD1 (with a catalytic dead mutation) in complex with a peptide substrate (open conformation)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wang, L, Toutkoushian, H, Belyy, V, Kokontis, C, Walter, P.
Deposit date:2022-04-16
Release date:2022-06-15
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.
Elife, 11, 2022
7UPR
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BU of 7upr by Molmil
Human mitochondrial AAA protein ATAD1 (with a catalytic dead mutation) in complex with a peptide substrate (closed conformation)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Outer mitochondrial transmembrane helix translocase, ...
Authors:Wang, L, Toutkoushian, H, Belyy, V, Kokontis, C, Walter, P.
Deposit date:2022-04-16
Release date:2022-06-15
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.
Elife, 11, 2022
6MIX
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BU of 6mix by Molmil
Human TRPM2 ion channel in apo state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIZ
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BU of 6miz by Molmil
Human TRPM2 ion channel in an ADPR-bound state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6WM4
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BU of 6wm4 by Molmil
Human V-ATPase in state 3 with SidK and ADP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WLZ
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BU of 6wlz by Molmil
The V1 region of human V-ATPase in state 1 (focused refinement)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SidK, V-type proton ATPase catalytic subunit A, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WM2
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BU of 6wm2 by Molmil
Human V-ATPase in state 1 with SidK and ADP
Descriptor: (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WM3
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BU of 6wm3 by Molmil
Human V-ATPase in state 2 with SidK and ADP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WLW
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BU of 6wlw by Molmil
The Vo region of human V-ATPase in state 1 (focused refinement)
Descriptor: (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, L, Wu, H, Fu, T.-M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6JFI
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BU of 6jfi by Molmil
The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex
Descriptor: FabZK2B10 heavy chain, FabZK2B10 light chain, ZIKV structural protein E, ...
Authors:Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q.
Deposit date:2019-02-08
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
6JEP
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BU of 6jep by Molmil
Structure of a neutralizing antibody bound to the Zika envelope protein domain III
Descriptor: Genome polyprotein, heavy chain of Fab ZK2B10, light chain of Fab ZK2B10
Authors:Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q.
Deposit date:2019-02-07
Release date:2019-05-15
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.316 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019

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