Author results

4NNK
  • Download 4nnk
  • View 4nnk
Molmil generated image of 4nnk
STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
分子名称:30S ribosomal protein S1
著者Yang, J., Liu, Y., Cai, Q., Lin, D.
登録日2013-11-18
公開日2014-12-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
5EGN
  • Download 5egn
  • View 5egn
Molmil generated image of 5egn
EST816 AS AN N-ACYL HOMOSERINE LACTONE DEGRADING ENZYME
分子名称:Esterase
著者Xie, W., Liu, X., Cao, L., Liu, Y.
登録日2015-10-27
公開日2016-11-02
実験手法X-RAY DIFFRACTION (2.636 Å)
主引用文献Est816 as an N-Acyl homoserine lactone degrading enzyme
To Be Published
1J48
  • Download 1j48
  • View 1j48
Molmil generated image of 1j48
CRYSTAL STRUCTURE OF APO-C1027
分子名称:Apoprotein of C1027
著者Chen, Y., Li, J., Liu, Y., Bartlam, M., Gao, Y., Jin, L., Tang, H., Shao, Y., Zhen, Y., Rao, Z.
登録日2001-07-30
公開日2003-06-03
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
4H52
  • Download 4h52
  • View 4h52
Molmil generated image of 4h52
WILD-TYPE INFLUENZA N2 NEURAMINIDASE COVALENT COMPLEX WITH 3-FLUORO-NEU5AC
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Vavricka, C.J., Liu, Y., Kiyota, H., Sriwilaijaroen, N., Qi, J., Tanaka, K., Wu, Y., Li, Q., Li, Y., Yan, J., Suzuki, Y., Gao, G.F.
登録日2012-09-18
公開日2013-02-20
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013
4H53
  • Download 4h53
  • View 4h53
Molmil generated image of 4h53
INFLUENZA N2-TYR406ASP NEURAMINIDASE IN COMPLEX WITH BETA-NEU5AC
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Vavricka, C.J., Liu, Y., Kiyota, H., Sriwilaijaroen, N., Qi, J., Tanaka, K., Wu, Y., Li, Q., Li, Y., Yan, J., Suzuki, Y., Gao, G.F.
登録日2012-09-18
公開日2013-02-20
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013
4IH1
  • Download 4ih1
  • View 4ih1
Molmil generated image of 4ih1
CRYSTAL STRUCTURE OF KARRIKIN INSENSITIVE 2 (KAI2) FROM ARABIDOPSIS THALIANA
分子名称:Hydrolase, alpha/beta fold family protein
著者Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH4
  • Download 4ih4
  • View 4ih4
Molmil generated image of 4ih4
CRYSTAL STRUCTURE OF ARABIDOPSIS DWARF14 ORTHOLOGUE, ATD14
分子名称:AT3g03990/T11I18_10
著者Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH9
  • Download 4ih9
  • View 4ih9
Molmil generated image of 4ih9
CRYSTAL STRUCTURE OF RICE DWARF14 (D14)
分子名称:Dwarf 88 esterase
著者Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IHA
  • Download 4iha
  • View 4iha
Molmil generated image of 4iha
CRYSTAL STRUCTURE OF RICE DWARF14 (D14) IN COMPLEX WITH A GR24 HYDROLYSIS INTERMEDIATE
分子名称:Dwarf 88 esterase, (2R,3R)-2,4,4-trihydroxy-3-methylbutanal
著者Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
登録日2012-12-18
公開日2013-01-23
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4LX3
  • Download 4lx3
  • View 4lx3
Molmil generated image of 4lx3
CONSERVED RESIDUES THAT MODULATE PROTEIN TRANS-SPLICING OF NPU DNAE SPLIT INTEIN
分子名称:DNA polymerase III, alpha subunit, Nucleic acid binding, ...
著者Wu, Q., Gao, Z., Wei, Y., Ma, G., Zheng, Y., Dong, Y., Liu, Y.
登録日2013-07-29
公開日2014-06-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conserved Residues that Modulate Protein trans-Splicing of Npu DnaE Split Intein
Biochem.J., 2014
5DJ5
  • Download 5dj5
  • View 5dj5
Molmil generated image of 5dj5
CRYSTAL STRUCTURE OF RICE DWARF14 IN COMPLEX WITH SYNTHETIC STRIGOLACTONE GR24
分子名称:Probable strigolactone esterase D14, (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one
著者Zhou, X.E., Zhao, L.-H., Yi, W., Wu, Z.-S., Liu, Y., Kang, Y., Hou, L., de Waal, P.W., Li, S., Jiang, Y., Melcher, K., Xu, H.E.
登録日2015-09-01
公開日2015-10-28
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.
Cell Res., 25, 2015
1C76
  • Download 1c76
  • View 1c76
Molmil generated image of 1c76
STAPHYLOKINASE (SAK) MONOMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
1C77
  • Download 1c77
  • View 1c77
Molmil generated image of 1c77
STAPHYLOKINASE (SAK) DIMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C78
  • Download 1c78
  • View 1c78
Molmil generated image of 1c78
STAPHYLOKINASE (SAK) DIMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C79
  • Download 1c79
  • View 1c79
Molmil generated image of 1c79
STAPHYLOKINASE (SAK) DIMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1GHE
  • Download 1ghe
  • View 1ghe
Molmil generated image of 1ghe
CRYSTAL STRUCTURE OF TABTOXIN RESISTANCE PROTEIN COMPLEXED WITH AN ACYL COENZYME A
分子名称:ACETYLTRANSFERASE, ACETYL COENZYME *A
著者He, H., Ding, Y., Bartlam, M., Sun, F., Le, Y., Qin, X., Tang, H., Zhang, R., Joachimiak, A., Liu, Y., Zhao, N., Rao, Z.
登録日2000-12-13
公開日2003-01-14
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of Tabtoxin Resistance Protein Complexed with Acetyl Coenzyme A Reveals the Mechanism for beta-Lactam Acetylation
J.Mol.Biol., 325, 2003
1O5T
  • Download 1o5t
  • View 1o5t
Molmil generated image of 1o5t
CRYSTAL STRUCTURE OF THE AMINOACYLATION CATALYTIC FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
分子名称:Tryptophanyl-tRNA synthetase
著者Yu, Y., Liu, Y., Shen, N., Xu, X., Jia, J., Jin, Y., Arnold, E., Ding, J.
登録日2003-10-05
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment
J.BIOL.CHEM., 279, 2004
2XNI
  • Download 2xni
  • View 2xni
Molmil generated image of 2xni
PROTEIN-LIGAND COMPLEX OF A NOVEL MACROCYCLIC HCV NS3 PROTEASE INHIBITOR DERIVED FROM AMINO CYCLIC BORONATES
分子名称:NS3 PROTEASE, NS4A COFACTOR, (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Zhou, Y., Li, Q., Plattner, J.J., Baker, S.J., Zhang, S., Kazmierski, W.M., Wright, L.L., Smith, G.K., Grimes, R.M., Crosby, R.M., Creech, K.L., Carballo, L.H., Slater, M.J., Jarvest, R.L., Thommes, P., Hubbard, J.A., Convery, M.A., Nassau, P.M., McDowell, W., Skarzynski, T.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., Pennicott, L.E., Zou, W., Wright, J.
登録日2010-08-02
公開日2011-08-17
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
3H3B
  • Download 3h3b
  • View 3h3b
Molmil generated image of 3h3b
CRYSTAL STRUCTURE OF THE SINGLE-CHAIN FV (SCFV) FRAGMENT OF AN ANTI-ERBB2 ANTIBODY CHA21 IN COMPLEX WITH RESIDUES 1-192 OF ERBB2 EXTRACELLULAR DOMAIN
分子名称:Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21
著者Zhou, H., Liu, Y., Niu, L., Zhu, J., Teng, M.
登録日2009-04-16
公開日2010-04-28
最終更新日2011-09-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
3R45
  • Download 3r45
  • View 3r45
Molmil generated image of 3r45
STRUCTURE OF A CENP-A-HISTONE H4 HETERODIMER IN COMPLEX WITH CHAPERONE HJURP
分子名称:Histone H3-like centromeric protein A, Histone H4, Holliday junction recognition protein, ...
著者Hu, H., Liu, Y., Wang, M., Fang, J., Huang, H., Yang, N., Li, Y., Wang, J., Yao, X., Shi, Y., Li, G., Xu, R.M.
登録日2011-03-17
公開日2011-04-06
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Genes Dev., 25, 2011
4O46
  • Download 4o46
  • View 4o46
Molmil generated image of 4o46
14-3-3-GAMMA IN COMPLEX WITH INFLUENZA NS1 C-TERMINAL TAIL PHOSPHORYLATED AT S228
分子名称:14-3-3 protein gamma, Nonstructural protein 1, Unidentified polymer, ...
著者Qin, S., Liu, Y., Tempel, W., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2013-12-18
公開日2014-04-30
最終更新日2014-06-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
5H3V
  • Download 5h3v
  • View 5h3v
Molmil generated image of 5h3v
CRYSTAL STRUCTURE OF A TYPE IV SECRETION SYSTEM COMPONENT CAGX IN HELICOBACTER PYLORI
分子名称:Cag8, ISOPROPYL ALCOHOL, DI(HYDROXYETHYL)ETHER
著者Zhang, J., Wu, Y., Zhao, Y., Sun, L., Keegan, R.M., Liu, Y., Isupov, M.N.
登録日2016-10-27
公開日2017-04-12
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the type IV secretion system component CagX from Helicobacter pylori
Acta Crystallogr F Struct Biol Commun, 73, 2017
1GIS
  • Download 1gis
  • View 1gis
Molmil generated image of 1gis
A TRICHOSANTHIN(TCS) MUTANT(E85Q) COMPLEX STRUCTURE WITH 2'-DEOXY-ADENOSIN-5'-MONOPHOSPHATE
分子名称:RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE
著者Guo, Q., Liu, Y., Dong, Y., Rao, Z.
登録日2001-03-15
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16, 2003
1GIU
  • Download 1giu
  • View 1giu
Molmil generated image of 1giu
A TRICHOSANTHIN(TCS) MUTANT(E85R) COMPLEX STRUCTURE WITH ADENINE
分子名称:RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, ADENINE
著者Guo, Q., Liu, Y., Dong, Y., Rao, Z.
登録日2001-03-15
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16, 2003
1OYN
  • Download 1oyn
  • View 1oyn
Molmil generated image of 1oyn
CRYSTAL STRUCTURE OF PDE4D2 IN COMPLEX WITH (R,S)-ROLIPRAM
分子名称:cAMP-specific phosphodiesterase PDE4D2, ZINC ION, ROLIPRAM
著者Huai, Q., Wang, H., Sun, Y., Kim, H.Y., Liu, Y., Ke, H.
登録日2003-04-05
公開日2003-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Structure, 11, 2003