Author results

3H3B
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CRYSTAL STRUCTURE OF THE SINGLE-CHAIN FV (SCFV) FRAGMENT OF AN ANTI-ERBB2 ANTIBODY CHA21 IN COMPLEX WITH RESIDUES 1-192 OF ERBB2 EXTRACELLULAR DOMAIN
Descriptor:Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21
Authors:Zhou, H., Liu, Y., Niu, L., Zhu, J., Teng, M.
Deposit date:2009-04-16
Release date:2010-04-28
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
2HGF
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HAIRPIN LOOP CONTAINING DOMAIN OF HEPATOCYTE GROWTH FACTOR, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:HEPATOCYTE GROWTH FACTOR
Authors:Zhou, H., Mazzulla, M.J., Kaufman, J.D., Stahl, S.J., Wingfield, P.T., Rubin, J.S., Bottaro, D.P., Byrd, R.A.
Deposit date:1997-12-18
Release date:1998-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site.
Structure, 6, 1998
1T2M
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SOLUTION STRUCTURE OF THE PDZ DOMAIN OF AF-6
Descriptor:AF-6 protein
Authors:Zhou, H., Wu, J.H., Xu, Y.Q., Huang, A.D., Shi, Y.Y.
Deposit date:2004-04-22
Release date:2005-02-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J.Biol.Chem., 280, 2005
3PSM
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.98A CRYSTAL STRUCTURE OF A DIMERIC PLANT DEFENSIN SPE10
Descriptor:Defensin
Authors:Zhou, H., Song, X., Gong, W.
Deposit date:2010-12-01
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:0.98A crystal structure of a dimeric plant defensin SPE10
To be Published
3Q18
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HUMAN GLUTATHIONE TRANSFERASE O2
Descriptor:Glutathione S-transferase omega-2, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Zhou, H., Board, P.G., Oakley, A.J.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
3Q19
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HUMAN GLUTATHIONE TRANSFERASE O2
Descriptor:Glutathione S-transferase omega-2, GLUTATHIONE, CHLORIDE ION
Authors:Zhou, H., Board, P.G., Oakley, A.J.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
3QAG
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HUMAN GLUTATHIONE TRANSFERASE O2 WITH GLUTATHIONE -NEW CRYSTAL FORM
Descriptor:Glutathione S-transferase omega-2, GLUTATHIONE, DI(HYDROXYETHYL)ETHER, ...
Authors:Zhou, H., Board, P.G., Oakley, A.J.
Deposit date:2011-01-11
Release date:2012-01-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
4E5Y
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STRUCTURE OF HUMAN FX PROTEIN, THE KEY ENZYME IN THE BIOSYNTHESIS OF GDP-L-FUCOSE
Descriptor:GDP-L-fucose synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhou, H., He, J.H.
Deposit date:2012-03-15
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
To be Published
4HVC
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CRYSTAL STRUCTURE OF HUMAN PROLYL-TRNA SYNTHETASE IN COMPLEX WITH HALOFUGINONE AND ATP ANALOGUE
Descriptor:Bifunctional glutamate/proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ...
Authors:Zhou, H., Sun, L., Yang, X.L., Schimmel, P.
Deposit date:2012-11-06
Release date:2013-01-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.
Nature, 494, 2012
4XEM
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CRYSTAL STRUCTURE OF WILD TYPE HUMAN ALARS CATALYTIC DOMAIN
Descriptor:Alanine--tRNA ligase, cytoplasmic, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, ...
Authors:Zhou, H., He, W., Yang, X.L.
Deposit date:2014-12-24
Release date:2016-02-17
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Crystal structure of wild type human AlaRS catalytic domain
To Be Published
6A68
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THE CRYSTAL STRUCTURE OF RAT CALCIUM-DEPENDENT ACTIVATOR PROTEIN FOR SECRETION (CAPS) DAMH DOMAIN
Descriptor:Calcium-dependent secretion activator 1, POTASSIUM ION
Authors:Zhou, H., Wei, Z.Q., Yao, D.Q., Zhang, R.G., Ma, C.
Deposit date:2018-06-26
Release date:2019-03-13
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Cell Rep, 26, 2019
6J11
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MERS-COV SPIKE N-TERMINAL DOMAIN AND 7D10 SCFV COMPLEX
Descriptor:N-terminal domain of Spike glycoprotein, VH of 7D10, VL of 7D10, ...
Authors:Zhou, H., Zhang, S., Zhang, S., Tang, W., Wang, X.
Deposit date:2018-12-27
Release date:2019-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein.
Nat Commun, 10, 2019
6KJ1
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200KV MICROED STRUCTURE OF FUS (37-42) SYSGYS SOLVED FROM MERGED DATASETS AT 0.65 A
Descriptor:RNA-binding protein FUS
Authors:Zhou, H., Luo, F., Luo, Z., Li, D., Liu, C., Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2019-11-20
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ2
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200KV MICROED STRUCTURE OF FUS (37-42) SYSGYS SOLVED FROM SINGLE CRYSTAL AT 0.67 A
Descriptor:RNA-binding protein FUS
Authors:Zhou, H., Luo, F., Luo, Z., Li, D., Liu, C., Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2019-11-20
Method:ELECTRON CRYSTALLOGRAPHY (0.67 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ3
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120KV MICROED STRUCTURE OF FUS (37-42) SYSGYS SOLVED FROM MERGED DATASETS AT 0.60 A
Descriptor:RNA-binding protein FUS
Authors:Zhou, H., Luo, F., Luo, Z., Li, D., Liu, C., Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2019-11-20
Method:ELECTRON CRYSTALLOGRAPHY (0.6 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ4
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120KV MICROED STRUCTURE OF FUS (37-42) SYSGYS SOLVED FROM SINGLE CRYSTAL AT 0.65 A
Descriptor:RNA-binding protein FUS
Authors:Zhou, H., Luo, F., Luo, Z., Li, D., Liu, C., Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2019-11-20
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6LAV
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MICROED STRUCTURE OF LYSOZYME AT 1.73A DETERMAINED USING CRYSTAL LAMELLAS PREPARED BY FOCUSED ION BEAM MILLING
Descriptor:Lysozyme C, ACETATE ION
Authors:Zhou, H., Luo, Z., Li, X.
Deposit date:2019-11-13
Release date:2019-11-27
Method:ELECTRON CRYSTALLOGRAPHY (1.73 Å)
Cite:Using focus ion beam to prepare crystal lamella for electron diffraction.
J. Struct. Biol., 205, 2019
6LAW
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MICROED STRUCTURE OF PROTEINASE K AT 1.50A DETERMAINED USING CRYSTAL LAMELLAS PREPARED BY FOCUSED ION BEAM MILLING
Descriptor:Proteinase K, SULFATE ION
Authors:Zhou, H., Luo, Z., Li, X.
Deposit date:2019-11-13
Release date:2019-12-04
Method:ELECTRON CRYSTALLOGRAPHY (1.5 Å)
Cite:Using focus ion beam to prepare crystal lamella for electron diffraction.
J. Struct. Biol., 205, 2019
5WXB
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CRYSTAL STRUCTURE OF ZIKV MTASE IN COMPLEX WITH SAH
Descriptor:MRNA cap 0-1 NS5-type MT, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yang, H., Wang, L., Zhou, H.
Deposit date:2017-01-07
Release date:2017-05-17
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:The conformational changes of Zika virus methyltransferase upon converting SAM to SAH
Oncotarget, 8, 2017
5HXW
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L-AMINO ACID DEAMINASE FROM PROTEUS VULGARIS
Descriptor:L-amino acid deaminase, FLAVIN-ADENINE DINUCLEOTIDE, CETYL-TRIMETHYL-AMMONIUM
Authors:Zhou, H., Ju, Y., Niu, L., Teng, M.
Deposit date:2016-01-31
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
5I39
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HIGH RESOLUTION STRUCTURE OF L-AMINO ACID DEAMINASE FROM PROTEUS VULGARIS WITH THE DELETION OF THE SPECIFIC INSERTION SEQUENCE
Descriptor:L-amino acid deaminase, FLAVIN-ADENINE DINUCLEOTIDE, 1,2-ETHANEDIOL
Authors:Zhou, H., Ju, Y., Niu, L., Teng, M.
Deposit date:2016-02-10
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
5V58
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CRYSTAL STRUCTURE OF HUMAN PROLYL-TRNA SYNTHETASE IN COMPLEX WITH AZE-SA
Descriptor:Bifunctional glutamate/proline--tRNA ligase, 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine, ZINC ION
Authors:Zhou, H., Song, Y., Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
5V59
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF HUMAN ALARS IN COMPLEX WITH AZE-SA
Descriptor:Alanine--tRNA ligase, cytoplasmic, 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine
Authors:Zhou, H., Song, Y., Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
6PWC
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A COMPLEX STRUCTURE OF ARRESTIN-2 BOUND TO NEUROTENSIN RECEPTOR 1
Descriptor:Neurotensin receptor type 1, Neurotensin peptide, Beta-arrestin-1, ...
Authors:Yin, W., Li, Z., Jin, M., Yin, Y.-L., de Waal, P.W., Pal, K., Gao, X., He, Y., Gao, J., Wang, X., Zhang, Y., Zhou, H., Melcher, K., Jiang, Y., Cong, Y., Zhou, X.E., Yu, X., Xu, H.E.
Deposit date:2019-07-22
Release date:2019-12-04
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:A complex structure of arrestin-2 bound to a G protein-coupled receptor
To Be Published
6IPX
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CRYSTAL STRUCTURE OF THE APO FORM TRANSCRIPTION FACTOR
Descriptor:AimR transcriptional regulator
Authors:Oy, S.Y., Zhen, X., Zhou, H., Ding, W.
Deposit date:2018-11-05
Release date:2019-01-23
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages.
Protein Cell, 10, 2019