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5FO7
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BU of 5fo7 by Molmil
Crystal Structure of Human Complement C3b at 2.8 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
2XWA
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BU of 2xwa by Molmil
Crystal Structure of Complement Factor D Mutant R202A
Descriptor: COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWJ
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BU of 2xwj by Molmil
Crystal Structure of Complement C3b in Complex with Factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-04
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWB
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BU of 2xwb by Molmil
Crystal Structure of Complement C3b in complex with Factors B and D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XW9
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BU of 2xw9 by Molmil
Crystal Structure of Complement Factor D mutant S183A
Descriptor: COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
5FOB
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BU of 5fob by Molmil
Crystal Structure of Human Complement C3b in complex with Smallpox Inhibitor of Complement (SPICE)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COMPLEMENT C3 BETA CHAIN, ...
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOA
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BU of 5foa by Molmil
Crystal Structure of Human Complement C3b in complex with DAF (CCP2-4)
Descriptor: COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, ...
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.188 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO8
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BU of 5fo8 by Molmil
Crystal Structure of Human Complement C3b in Complex with MCP (CCP1-4)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3, ...
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO9
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BU of 5fo9 by Molmil
Crystal Structure of Human Complement C3b in Complex with CR1 (CCP15- 17)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, ...
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
2V1D
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BU of 2v1d by Molmil
Structural basis of LSD1-CoREST selectivity in histone H3 recognition
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, HISTONE H3.1T, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Forneris, F, Binda, C, Adamo, A, Battaglioli, E, Mattevi, A.
Deposit date:2007-05-23
Release date:2007-05-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Lsd1-Corest Selectivity in Histone H3 Recognition.
J.Biol.Chem., 282, 2007
2VFT
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BU of 2vft by Molmil
Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sorbitol
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE, ...
Authors:Forneris, F, Mattevi, A.
Deposit date:2007-11-05
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase.
Biochemistry, 47, 2008
2VFS
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BU of 2vfs by Molmil
Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Xylitol
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE, ...
Authors:Forneris, F, Mattevi, A.
Deposit date:2007-11-05
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase.
Biochemistry, 47, 2008
2VFU
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BU of 2vfu by Molmil
Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Mannitol
Descriptor: D-MANNITOL, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE
Authors:Forneris, F, Mattevi, A.
Deposit date:2007-11-05
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase.
Biochemistry, 47, 2008
2VFR
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BU of 2vfr by Molmil
Alditol Oxidase from Streptomyces coelicolor A3(2): Native Enzyme
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE
Authors:Forneris, F, Mattevi, A.
Deposit date:2007-11-05
Release date:2008-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase.
Biochemistry, 47, 2008
2VFV
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BU of 2vfv by Molmil
Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sulphite
Descriptor: (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, CHLORIDE ION, XYLITOL OXIDASE
Authors:Forneris, F, Mattevi, A.
Deposit date:2007-11-05
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase.
Biochemistry, 47, 2008
4CBN
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BU of 4cbn by Molmil
Crystal structure of Complement Factor D mutant R202A after conventional refinement
Descriptor: COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F, Burnley, B.T, Gros, P.
Deposit date:2013-10-15
Release date:2013-12-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ensemble Refinement Shows Conformational Flexibility in Crystal Structures of Human Complement Factor D
Acta Crystallogr.,Sect.D, 70, 2014
4CBO
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BU of 4cbo by Molmil
Crystal structure of Complement Factor D mutant R202A after ensemble refinement
Descriptor: COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F, Burnley, B.T, Gros, P.
Deposit date:2013-10-15
Release date:2013-12-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ensemble Refinement Shows Conformational Flexibility in Crystal Structures of Human Complement Factor D
Acta Crystallogr.,Sect.D, 70, 2014
8ONE
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BU of 8one by Molmil
Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose
Descriptor: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mattoteia, D, De Marco, M, Pinnola, A, Faravelli, S, Scietti, L, Forneris, F.
Deposit date:2023-04-02
Release date:2023-07-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity.
Int J Mol Sci, 24, 2023
7AH1
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BU of 7ah1 by Molmil
L19 diabody fragment from immunocytokine L19-IL2
Descriptor: Anti-(ED-B) scFV
Authors:Ongaro, T, Guarino, S.R, Scietti, L, Palamini, M, Wulhfard, S, Villa, A, Neri, D, Forneris, F.
Deposit date:2020-09-23
Release date:2021-02-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inference of molecular structure for characterization and improvement of clinical grade immunocytokines.
J.Struct.Biol., 213, 2021
5FUS
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BU of 5fus by Molmil
Crystal structure of B. cenocepacia DfsA
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, LAURIC ACID, ...
Authors:Spadaro, F, Scoffone, V.C, Chiarelli, L.R, Fumagalli, M, Buroni, S, Riccardi, G, Forneris, F.
Deposit date:2016-01-29
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Crystal Structure of Burkholderia Cenocepacia Dfsa Provides Insights Into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis.
Biochemistry, 55, 2016
8AS0
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BU of 8as0 by Molmil
PD-1 extracellular domain in complex with Fab fragment from D12 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ongaro, T, Scietti, L, Pluss, L, Peissert, F, Villa, A, Puca, E, De Luca, R, Neri, D, Forneris, F.
Deposit date:2022-08-17
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Selection of a PD-1 blocking antibody from a novel fully human phage display library.
Protein Sci., 31, 2022
7TDR
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BU of 7tdr by Molmil
Labrum-interacting protein from saliva LIPS-2 (34K-2) from Aedes albopictus, selenomethionine derivative
Descriptor: 34k2 salivary protein, NITRATE ION, SULFATE ION
Authors:Gabrieli, P, Forneris, F.
Deposit date:2022-01-03
Release date:2022-07-27
Last modified:2022-09-07
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A salivary factor binds a cuticular protein and modulates biting by inducing morphological changes in the mosquito labrum.
Curr.Biol., 32, 2022
7TDS
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BU of 7tds by Molmil
Labrum-interacting protein from saliva LIPS-2 (34K-2) from Aedes albopictus, native data
Descriptor: 34k2 salivary protein, NITRATE ION, SODIUM ION, ...
Authors:Gabrieli, P, Forneris, F.
Deposit date:2022-01-03
Release date:2022-07-27
Last modified:2022-09-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A salivary factor binds a cuticular protein and modulates biting by inducing morphological changes in the mosquito labrum.
Curr.Biol., 32, 2022
7TNG
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BU of 7tng by Molmil
Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1)
Descriptor: Inactive tyrosine-protein kinase transmembrane receptor ROR1
Authors:Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F.
Deposit date:2022-01-21
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1)
Acta Crystallogr.,Sect.F, 78, 2022
2XAJ
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BU of 2xaj by Molmil
Crystal structure of LSD1-CoREST in complex with (-)-trans-2- phenylcyclopropyl-1-amine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, PHENYLETHYLENECARBOXYLIC ACID, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010

 

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