Author results

6QD8
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EM STRUCTURE OF A EBOV-GP BOUND TO 4M0368 NEUTRALIZING ANTIBODY
Descriptor:Light chain, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, Envelope glycoprotein, ...
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
6QD7
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EM STRUCTURE OF A EBOV-GP BOUND TO 3T0331 NEUTRALIZING ANTIBODY
Descriptor:Light chain, Heavy chain, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, ...
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV.
Nat. Med., 2019
6QCU
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CRYSTAL STRUCTURE OF A FAB PORTION OF THE ANTI EBOV 3T0331 ANTIBODY
Descriptor:Light chain, Heavy chain, SULFATE ION
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2018-12-31
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
6GEZ
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THE STRUCTURE OF TWITCH-2B N532F
Descriptor:Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein, CALCIUM ION, FORMIC ACID
Authors:Trigo Mourino, P., Paulat, M., Thestrup, T., Griesbeck, O., Griesinger, C., Becker, S.
Deposit date:2018-04-27
Release date:2019-08-21
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Dynamic tuning of FRET in a green fluorescent protein biosensor.
Sci Adv, 5, 2019
6GEL
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THE STRUCTURE OF TWITCH-2B
Descriptor:Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein, CALCIUM ION, GLYCEROL, ...
Authors:Trigo Mourino, P., Paulat, M., Thestrup, T., Griesbeck, O., Griesinger, C., Becker, S.
Deposit date:2018-04-26
Release date:2019-08-21
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Dynamic tuning of FRET in a green fluorescent protein biosensor.
Sci Adv, 5, 2019
6FCG
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CRYSTAL STRUCTURE OF AN ENDO-LAMINARINASE FROM FORMOSA HEL1_33_131
Descriptor:Glycoside hydrolase, GH17 family, CALCIUM ION
Authors:Becker, S., Robb, C.S., Hehemann, J.H.
Deposit date:2017-12-20
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Adaptive mechanisms that provide competitive advantages to marine bacteroidetes during microalgal blooms.
ISME J, 12, 2018
6EHM
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MODEL OF THE EBOLA VIRUS NUCLEOCAPSID SUBUNIT FROM RECOMBINANT VIRUS-LIKE PARTICLES
Descriptor:Nucleoprotein, Membrane-associated protein VP24
Authors:Wan, W., Kolesnikova, L., Clarke, M., Koehler, A., Noda, T., Becker, S., Briggs, J.A.G.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
6EHL
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MODEL OF THE EBOLA VIRUS NUCLEOPROTEIN IN RECOMBINANT NUCLEOCAPSID-LIKE ASSEMBLIES
Descriptor:Nucleoprotein
Authors:Wan, W., Kolesnikova, L., Clarke, M., Koehler, A., Noda, T., Becker, S., Briggs, J.A.G.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
5NWX
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Deposit date:2017-05-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5NWM
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Becker, S., Griesinger, C.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5JDP
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E73V MUTANT OF THE HUMAN VOLTAGE-DEPENDENT ANION CHANNEL
Descriptor:Voltage-dependent anion-selective channel protein 1
Authors:Jaremko, M., Jaremko, L., Villinger, S., Schmidt, C., Giller, K., Griesinger, C., Becker, S., Zweckstetter, M.
Deposit date:2016-04-17
Release date:2016-08-10
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
Angew.Chem.Int.Ed.Engl., 55, 2016
5FQ1
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STRUCTURE OF THE CYTOPLASMIC PAS DOMAIN OF THE GEOBACILLUS THERMODENITRIFICANS HISTIDINE KINASE CITA
Descriptor:HISTIDINE KINASE, GLYCEROL, PHOSPHATE ION
Authors:Schomburg, B., Giller, K., Becker, S.
Deposit date:2015-12-03
Release date:2017-01-11
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Cryogenic optical localization provides 3D protein structure data with Angstrom resolution.
Nat. Methods, 14, 2017
5C58
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A DOUBLE MUTANT OF SERRATIA MARCESCENS HEMOPHORE RECEPTOR HASR IN COMPLEX WITH ITS HEMOPHORE HASA AND HEME
Descriptor:HasR protein, Hemophore HasA, PROTOPORPHYRIN IX CONTAINING FE
Authors:Becker, S., Diederichs, K., Welte, W.
Deposit date:2015-06-19
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Binding of HasA by its transmembrane receptor HasR follows a conformational funnel mechanism
To Be Published
5ABS
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CRYSTAL STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85 IN SPACE GROUP P321
Descriptor:SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1, ZINC ION
Authors:Wong, L., Habeck, M., Griesinger, C., Becker, S.
Deposit date:2015-08-07
Release date:2016-07-13
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Adaptor Protein Cin85 Assembles Intracellular Signaling Clusters for B Cell Activation.
Sci.Signal., 9, 2016
4ZG4
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MYOSIN VC PRE-POWERSTROKE
Descriptor:myosin-Vc, MAGNESIUM ION, VANADATE ION, ...
Authors:Ropars, V., Pylypenko, O., Sweeney, L., Houdusse, A.
Deposit date:2015-04-22
Release date:2016-03-23
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Force-producing ADP state of myosin bound to actin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YXS
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N-BENZYL-9H-PURIN-6-AMINE
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-20
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4YXR
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CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH INHIBITOR.
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-methyl-2H-indazole
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-27
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
Descriptor:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
Authors:Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
Deposit date:2014-05-23
Release date:2014-08-27
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
4MIV
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CRYSTAL STRUCTURE OF SULFAMIDASE, CRYSTAL FORM L
Descriptor:N-sulphoglucosamine sulphohydrolase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sidhu, N.S., Uson, I., Schreiber, K., Proepper, K., Becker, S., Sheldrick, G.M., Gaertner, J., Kraetzner, R., Steinfeld, R.
Deposit date:2013-09-02
Release date:2014-05-14
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.
Acta Crystallogr.,Sect.D, 70, 2014
4MHX
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CRYSTAL STRUCTURE OF SULFAMIDASE
Descriptor:N-sulphoglucosamine sulphohydrolase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sidhu, N.S., Uson, I., Schreiber, K., Proepper, K., Becker, S., Gaertner, J., Kraetzner, R., Steinfeld, R., Sheldrick, G.M.
Deposit date:2013-08-30
Release date:2014-05-14
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.
Acta Crystallogr.,Sect.D, 70, 2014
4C4Z
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH A8
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 1-ethyl-3-naphthalen-1-ylurea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4C4Y
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH A4
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4C4X
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CRYSTAL STRUCTURE OF HUMAN BIFUNCTIONAL EPOXIDE HYDROXYLASE 2 COMPLEXED WITH C9
Descriptor:BIFUNCTIONAL EPOXIDE HYDROLASE 2, 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea
Authors:Pilger, J., Mazur, A., Monecke, P., Schreuder, H., Elshorst, B., Langer, T., Schiffer, A., Krimm, I., Wegstroth, M., Lee, D., Hessler, G., Wendt, K.-U., Becker, S., Griesinger, C.
Deposit date:2013-09-09
Release date:2014-10-01
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
3UFE
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STRUCTURE OF TRANSCRIPTIONAL ANTITERMINATOR (BGLG-FAMILY) AT 1.5 A RESOLUTION
Descriptor:Transcriptional antiterminator (BGLG family), CHLORIDE ION, PHOSPHATE ION, ...
Authors:Grosse, C., Himmel, S., Becker, S., Sheldrick, G.M., Uson, I.
Deposit date:2011-11-01
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of transcriptional antiterminator (BGLG-family) at 1.5 A resolution
To be Published
3RIO
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CRYSTAL STRUCTURE OF GLCT CAT-PRDI
Descriptor:PtsGHI operon antiterminator, GLYCEROL
Authors:Himmel, S., Grosse, C., Wolff, S., Becker, S.
Deposit date:2011-04-14
Release date:2012-05-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure of the RBD-PRDI fragment of the antiterminator protein GlcT.
Acta Crystallogr.,Sect.F, 68, 2012