Author results

2HL0
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH SERYL-3'-AMINOADENOSINE
Descriptor:Threonyl-tRNA synthetase, SERINE-3'-AMINOADENOSINE
Authors:Hussain, T., Kruparani, S.P., Pal, B., Sankaranarayanan, R.
Deposit date:2006-07-06
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea
Embo J., 25, 2006
2HL1
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH SERYL-3'-AMINOADENOSINE
Descriptor:Threonyl-tRNA synthetase, SERINE-3'-AMINOADENOSINE
Authors:Hussain, T., Kruparani, S.P., Pal, B., Sankaranarayanan, R.
Deposit date:2006-07-06
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea
Embo J., 25, 2006
2HL2
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH AN ANALOG OF SERYLADENYLATE
Descriptor:Threonyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE
Authors:Hussain, T., Kruparani, S.P., Pal, B., Sankaranarayanan, R.
Deposit date:2006-07-06
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea
Embo J., 25, 2006
3J80
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CRYOEM STRUCTURE OF 40S-EIF1-EIF1A PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-28
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3J81
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CRYOEM STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-29
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3PD2
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH SERYL-3'-AMINOADENOSINE
Descriptor:Threonyl-tRNA synthetase, SERINE-3'-AMINOADENOSINE
Authors:Hussain, T., Kamarthapu, V., Kruparani, S.P., Sankaranarayanan, R.
Deposit date:2010-10-22
Release date:2010-12-08
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mechanistic insights into cognate substrate discrimination during proofreading in translation
Proc.Natl.Acad.Sci.USA, 107, 2010
3PD3
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH THREONYL-3'-AMINOADENOSINE
Descriptor:Threonyl-tRNA synthetase, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Hussain, T., Kamarthapu, V., Kruparani, S.P., Sankaranarayanan, R.
Deposit date:2010-10-22
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mechanistic insights into cognate substrate discrimination during proofreading in translation
Proc.Natl.Acad.Sci.USA, 2010
3PD4
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH GLYCYL-3'-AMINOADENOSINE
Descriptor:Threonyl-tRNA synthetase, 3'-deoxy-3'-(glycylamino)adenosine
Authors:Hussain, T., Kamarthapu, V., Kruparani, S.P., Sankaranarayanan, R.
Deposit date:2010-10-22
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic insights into cognate substrate discrimination during proofreading in translation
Proc.Natl.Acad.Sci.USA, 2010
3PD5
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH AN ANALOG OF THREONYL-ADENYLATE
Descriptor:Threonyl-tRNA synthetase, GLYCEROL, 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE
Authors:Hussain, T., Kamarthapu, V., Kruparani, S.P., Sankaranarayanan, R.
Deposit date:2010-10-22
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Mechanistic insights into cognate substrate discrimination during proofreading in translation
Proc.Natl.Acad.Sci.USA, 2010
5LMN
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1A)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMO
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1B)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMP
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1C)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (5.35 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMQ
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX, OPEN FORM (STATE-2A)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMR
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-2B)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMS
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-2C)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMT
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMU
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STRUCTURE OF BACTERIAL 30S-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX, CLOSED FORM (STATE-4)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMV
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STRUCTURE OF BACTERIAL 30S-IF1-IF2-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-III)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
4RRQ
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K121M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI WITH L-SER3AA
Descriptor:Threonine--tRNA ligase, SERINE-3'-AMINOADENOSINE
Authors:Hussain, T., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRR
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K121M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI WITH L-THR3AA
Descriptor:Threonine--tRNA ligase, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Hussain, T., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
3J6B
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STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ...
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
3JAM
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CRYOEM STRUCTURE OF 40S-EIF1A-EIF1 COMPLEX FROM YEAST
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAP
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION
Descriptor:Met-tRNAi (U31:A39 variant), 18S rRNA, mRNA, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAQ
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN CONFORMATION
Descriptor:Met-tRNAi, 18S rRNA, mRNA, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
4V8Y
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
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