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1MF2
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BU of 1mf2 by Molmil
ANTI HIV1 PROTEASE FAB COMPLEX
Descriptor: MONOCLONAL ANTIBODY F11.2.32
Authors:Lescar, J, Bentley, G.A.
Deposit date:1996-12-27
Release date:1997-12-31
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
J.Mol.Biol., 267, 1997
1FBI
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BU of 1fbi by Molmil
CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME
Descriptor: GUINEA FOWL LYSOZYME, IGG1 F9.13.7 FAB (HEAVY CHAIN), IGG1 F9.13.7 FAB (LIGHT CHAIN)
Authors:Lescar, J, Alzari, P.M.
Deposit date:1995-01-19
Release date:1995-02-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme.
J.Biol.Chem., 270, 1995
1N4X
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BU of 1n4x by Molmil
Structure of scFv 1696 at acidic pH
Descriptor: CHLORIDE ION, immunoglobulin heavy chain variable region, immunoglobulin kappa chain variable region
Authors:Lescar, J, Brynda, J, Fabry, M, Horejsi, M, Rezacova, P, Sedlacek, J, Bentley, G.A.
Deposit date:2002-11-02
Release date:2003-06-10
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases.
Acta Crystallogr.,Sect.D, 59, 2003
2HRP
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BU of 2hrp by Molmil
ANTIGEN-ANTIBODY COMPLEX
Descriptor: HIV-1 PROTEASE PEPTIDE, MONOCLONAL ANTIBODY F11.2.32
Authors:Lescar, J, Bentley, G.A.
Deposit date:1996-12-27
Release date:1997-12-31
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
J.Mol.Biol., 267, 1997
1CL7
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BU of 1cl7 by Molmil
ANTI HIV1 PROTEASE FAB
Descriptor: PROTEIN (IGG1 ANTIBODY 1696 (constant heavy chain)), PROTEIN (IGG1 ANTIBODY 1696 (light chain)), PROTEIN (IGG1 ANTIBODY 1696 (variable heavy chain))
Authors:Lescar, J, Bentley, G.A.
Deposit date:1999-05-06
Release date:2000-01-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
Protein Sci., 8, 1999
1I9W
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BU of 1i9w by Molmil
CRYSTAL STRUCTURE OF THE FUSION GLYCOPROTEIN E1 FROM SEMLIKI FOREST VIRUS
Descriptor: FUSION PROTEIN E1
Authors:Lescar, J, Roussel, A, Wien, M.W, Navaza, J, Fuller, S.D, Wengler, G, Wengler, G, Rey, F.A.
Deposit date:2001-03-21
Release date:2002-04-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH.
Cell(Cambridge,Mass.), 105, 2001
1GNZ
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BU of 1gnz by Molmil
LECTIN I-B4 FROM GRIFFONIA SIMPLICIFOLIA (GS I-B4)METAL FREE FORM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GSI-B4 ISOLECTIN, PHOSPHATE ION
Authors:Lescar, J, Loris, R, Mitchell, E, Gautier, C, Imberty, A.
Deposit date:2001-10-11
Release date:2001-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Isolectins I-A and I-B of Griffonia (Bandeiraea) Simplicifolia. Crystal Structure of Metal-Free Gs I-B(4) and Molecular Basis for Metal Binding and Monosaccharide Specificity.
J.Biol.Chem., 277, 2002
1HHL
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BU of 1hhl by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES
Descriptor: GUINEA FOWL LYSOZYME
Authors:Alzari, P.M, Lescar, J.
Deposit date:1993-05-04
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of pheasant and guinea fowl egg-white lysozymes
Protein Sci., 3, 1994
6ID4
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BU of 6id4 by Molmil
Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Lescar, J, Wong, Y.H, Liew, C.W, Gu, Y, MacAry, P.A.
Deposit date:2018-09-08
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.
Nat Commun, 10, 2019
5JJS
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BU of 5jjs by Molmil
Dengue 3 NS5 protein with compound 27
Descriptor: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-{[(1R,3R)-3-methoxycyclohexyl]sulfonyl}benzamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Lescar, J, El Sahili, A.
Deposit date:2016-04-25
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
5JJR
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BU of 5jjr by Molmil
Dengue 3 NS5 protein with compound 29
Descriptor: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Lescar, J, El Sahili, A.
Deposit date:2016-04-25
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
1GHL
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BU of 1ghl by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES
Descriptor: PHEASANT EGG WHITE LYSOZYME
Authors:Alzari, P.M, Lescar, J.
Deposit date:1993-05-04
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of pheasant and guinea fowl egg-white lysozymes
Protein Sci., 3, 1994
2CGY
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BU of 2cgy by Molmil
STRUCTURE OF HELIX POMATIA AGGLUTININ WITH FORSMANN ANTIGEN
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, AGGLUTININ
Authors:Sanchez, J.-F, Lescar, J, Audfray, A, Gautier, C, Chazalet, V, Gagnon, J, Breton, C, Imberty, A, Mitchell, E.P.
Deposit date:2006-03-10
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Recognition of Breast and Colon Cancer Epitopes Tn Antigen and Forssman Disaccharide by Helix Pomatia Lectin.
Glycobiology, 17, 2007
2CGZ
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BU of 2cgz by Molmil
Structure of Helix Pomatia agglutinin with Tn antigen
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, AGGLUTININ, ...
Authors:Sanchez, J.-F, Lescar, J, Audfray, A, Gautier, C, Chazalet, V, Gagnon, J, Breton, C, Imberty, A, Mitchell, E.P.
Deposit date:2006-03-10
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Recognition of Breast and Colon Cancer Epitopes Tn Antigen and Forssman Disaccharide by Helix Pomatia Lectin.
Glycobiology, 17, 2007
5XGB
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BU of 5xgb by Molmil
Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa
Descriptor: Uncharacterized protein
Authors:Liu, C, Liew, C.W, Sreekanth, R, Lescar, J.
Deposit date:2017-04-13
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
2XBM
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BU of 2xbm by Molmil
Crystal structure of the dengue virus methyltransferase bound to a 5'- capped octameric RNA
Descriptor: 5'-(*G3AP*GP*AP*AP*CP*CP*UP*GP*A)-3', GLYCEROL, NONSTRUCTURAL PROTEIN NS5, ...
Authors:Yap, L.J, Luo, D.H, Chung, K.Y, Lim, S.P, Bodenreider, C, Noble, C, Shi, P.Y, Lescar, J.
Deposit date:2010-04-13
Release date:2010-09-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5'-Capped Octameric RNA
Plos One, 5, 2010
4V0R
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BU of 4v0r by Molmil
DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
Descriptor: FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
2ALA
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BU of 2ala by Molmil
Crystal structure of the Semliki Forest Virus envelope protein E1 in its monomeric conformation.
Descriptor: Structural polyprotein (P130)
Authors:Roussel, A, Lescar, J, Vaney, M.C, Wengler, G, Wengler, G, Rey, F.A.
Deposit date:2005-08-05
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.
Structure, 14, 2006
4URS
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BU of 4urs by Molmil
Crystal Structure of GGDEF domain from T.maritima
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE, ...
Authors:Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
Deposit date:2014-07-02
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
8HO4
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BU of 8ho4 by Molmil
Falcilysin in complex with MMV000848
Descriptor: (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol, 1,2-ETHANEDIOL, Falcilysin, ...
Authors:Lin, J.Q, Chung, Z, Lescar, J.
Deposit date:2022-12-09
Release date:2023-12-20
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.
Cell Chem Biol, 31, 2024
8HO5
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BU of 8ho5 by Molmil
Falcilysin in complex with MMV665806
Descriptor: (2S)-1-(2,3-dimethyl-1H-indol-1-yl)-3-{[(1S,2S)-2-methylcyclohexyl]amino}propan-2-ol, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Lin, J.Q, Chung, Z, Lescar, J.
Deposit date:2022-12-09
Release date:2023-12-20
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.
Cell Chem Biol, 31, 2024
4V0Q
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BU of 4v0q by Molmil
Dengue Virus Full Length NS5 Complexed with SAH
Descriptor: ACETATE ION, GLYCEROL, NS5 POLYMERASE, ...
Authors:Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
6ITO
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BU of 6ito by Molmil
Crystal structure of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, AMP and inhibitor Ribose 5-Phosphate
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, OXALATE ION, ...
Authors:Zhong, W, Cai, Q, El Sahili, A, Mu, Y, Lescar, J, Dedon, P.C.
Deposit date:2018-11-24
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.
J.Mol.Biol., 431, 2019
1YUK
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BU of 1yuk by Molmil
The crystal structure of the PSI/Hybrid domain/ I-EGF1 segment from the human integrin beta2 at 1.8 resolution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Integrin beta-2 A chain, Integrin beta-2 B chain
Authors:Shi, M, Sundramurthy, K, Liu, B, Tan, S.M, Law, S.K, Lescar, J.
Deposit date:2005-02-14
Release date:2005-07-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution
J.Biol.Chem., 280, 2005
6U5O
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BU of 6u5o by Molmil
Structure of the Human Metapneumovirus Polymerase bound to the phosphoprotein tetramer
Descriptor: Phosphoprotein, RNA-directed RNA polymerase L
Authors:Pan, J, Qian, X, Lattmann, S, Sahili, A.E, Yeo, T.H, Kalocsay, M, Fearns, R, Lescar, J.
Deposit date:2019-08-28
Release date:2019-09-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the human metapneumovirus polymerase phosphoprotein complex.
Nature, 577, 2020

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