1CL7
ANTI HIV1 PROTEASE FAB
Summary for 1CL7
Entry DOI | 10.2210/pdb1cl7/pdb |
Descriptor | PROTEIN (IGG1 ANTIBODY 1696 (light chain)), PROTEIN (IGG1 ANTIBODY 1696 (variable heavy chain)), PROTEIN (IGG1 ANTIBODY 1696 (constant heavy chain)) (3 entities in total) |
Functional Keywords | fab fragment, cross-reactivity, hiv1 protease, enzyme inhibition, immunoglobulin, immune system |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane; Single-pass membrane protein (Potential): P01869 |
Total number of polymer chains | 3 |
Total formula weight | 47660.99 |
Authors | Lescar, J.,Bentley, G.A. (deposition date: 1999-05-06, release date: 2000-01-12, Last modification date: 2023-08-09) |
Primary citation | Lescar, J.,Brynda, J.,Rezacova, P.,Stouracova, R.,Riottot, M.M.,Chitarra, V.,Fabry, M.,Horejsi, M.,Sedlacek, J.,Bentley, G.A. Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody. Protein Sci., 8:2686-2696, 1999 Cited by PubMed: 10631984PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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