Author results

1K9O
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CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX
分子名称:ALASERPIN, TRYPSIN II ANIONIC
著者Ye, S., Cech, A.L., Belmares, R., Bergstrom, R.C., Tong, Y., Corey, D.R., Kanost, M.R., Goldsmith, E.J.
登録日2001-10-29
公開日2001-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of a Michaelis serpin-protease complex.
Nat.Struct.Biol., 8, 2001
1M60
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SOLUTION STRUCTURE OF ZINC-SUBSTITUTED CYTOCHROME C
分子名称:Zinc-substituted cytochrome c, ZINC SUBSTITUTED HEME C
著者Qian, C., Yao, Y., Tong, Y., Wang, J., Tang, W.
登録日2002-07-11
公開日2002-08-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural analysis of zinc-substituted cytochrome c.
J.Biol.Inorg.Chem., 8, 2003
1NI1
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IMIDAZOLE AND CYANOPHENYL FARNESYL TRANSFERASE INHIBITORS
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Tong, Y., Lin, N.H., Wang, L., Hasvold, L., Wang, W., Leonard, N., Li, T., Li, Q., Cohen, J., Gu, W.Z., Zhang, H., Stoll, V., Bauch, J., Marsh, K., Rosenberg, S.H., Sham, H.L.
登録日2002-12-20
公開日2004-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Bioorg.Med.Chem.Lett., 13, 2003
1NMI
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SOLUTION STRUCTURE OF THE IMIDAZOLE COMPLEX OF ISO-1 CYTOCHROME C
分子名称:Cytochrome c, iso-1, IMIDAZOLE, ...
著者Yao, Y., Tong, Y., Liu, G., Wang, J., Zheng, J., Tang, W.
登録日2003-01-10
公開日2003-02-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the imidazole complex of iso-1 cytochrome c
To be Published
1Y9X
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SOLUTION STRUCTURE OF ARCHAEON DNA-BINDING PROTEIN SSH10B
分子名称:DNA/RNA-binding protein Alba 1
著者Cui, Q., Tong, Y., Wang, J.
登録日2004-12-16
公開日2005-06-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A stabilizing alpha/beta-hydrophobic core greatly contributes to hyperthermostability of archaeal [P62A]Ssh10b.
Biochemistry, 47, 2008
2IQJ
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CRYSTAL STRUCTURE OF THE GAP DOMAIN OF SMAP1L (LOC64744) STROMAL MEMBRANE-ASSOCIATED PROTEIN 1-LIKE
分子名称:Stromal membrane-associated protein 1-like, ZINC ION, BETA-MERCAPTOETHANOL, ...
著者Tong, Y., Dimov, S., Shen, L., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2006-10-13
公開日2006-10-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the GAP domain of SMAP1L (LOC64744) stromal membrane-associated protein 1-like
To be Published
2OLM
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ARFGAP DOMAIN OF HIV-1 REV BINDING PROTEIN
分子名称:Nucleoporin-like protein RIP, ZINC ION, SULFATE ION, ...
著者Tong, Y., Tempel, W., Shen, L., Dimov, S., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-01-19
公開日2007-01-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献ArfGap domain of HIV-1 Rev binding protein
To be Published
2E9N
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STRUCTURE OF H-CHK1 COMPLEXED WITH A767085
分子名称:Serine/threonine-protein kinase Chk1, 3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Bioorg.Med.Chem., 15, 2007
2E9O
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STRUCTURE OF H-CHK1 COMPLEXED WITH AA582939
分子名称:Serine/threonine-protein kinase Chk1, 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Bioorg.Med.Chem., 15, 2007
2E9P
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STRUCTURE OF H-CHK1 COMPLEXED WITH A771129
分子名称:Serine/threonine-protein kinase Chk1, 1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Based Design, Synthesis and Biological Evaluation of Potent and Selective Macrocyclic Chk1 Inhibitors
To be Published
2E9U
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STRUCTURE OF H-CHK1 COMPLEXED WITH A780125
分子名称:Serine/threonine-protein kinase Chk1, 18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE
著者Park, C.
登録日2007-01-27
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Design, Synthesis and Biological Evaluation of Potent Selective Macrocyclic Chk1 Inhibitors
To be Published
2E9V
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STRUCTURE OF H-CHK1 COMPLEXED WITH A859017
分子名称:Serine/threonine-protein kinase Chk1, 18-CHLORO-2-OXO-17-[(PYRIDIN-4-YLMETHYL)AMINO]-2,3,11,12,13,14-HEXAHYDRO-1H,10H-4,8-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECINE-7-CARBONITRILE
著者Park, C.
登録日2007-01-27
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Design, Synthesis and Biological Evaluation of Potent Selective Macrocyclic Chk1 Inhibitors
To be Published
2P57
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GAP DOMAIN OF ZNF289, AN ID1-REGULATED ZINC FINGER PROTEIN
分子名称:GTPase-activating protein ZNF289, ZINC ION, UNKNOWN ATOM OR ION
著者Tong, Y., Dimov, S., Shen, L., Zhu, H., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-03-14
公開日2007-03-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献GAP domain of ZNF289, an ID1-regulated zinc finger protein
To be Published
2PQE
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SOLUTION STRUCTURE OF PROLINE-FREE MUTANT OF STAPHYLOCOCCAL NUCLEASE
分子名称:Thermonuclease
著者Shan, L., Tong, Y., Xie, T., Wang, M., Wang, J.
登録日2007-05-01
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.
Biochemistry, 46, 2007
2JPH
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NMR SOLUTION STRUCTURE OF THE RHO GTPASE BINDING DOMAIN OF HUMAN PLEXIN-B1
分子名称:Plexin-B1
著者Tong, Y., Buck, M.
登録日2007-05-11
公開日2008-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Insights into Oncogenic Mutations of Plexin-B1 Based on the Solution Structure of the Rho GTPase Binding Domain
Structure, 16, 2008
2PZ9
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CRYSTAL STRUCTURE OF PUTATIVE TRANSCRIPTIONAL REGULATOR SCO4942 FROM STREPTOMYCES COELICOLOR
分子名称:Putative regulatory protein, SULFATE ION
著者Filippova, E.V., Chruszcz, M., Xu, X., Zheng, H., Cymborowski, M., Savchenko, A., Edwards, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
登録日2007-05-17
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In situ proteolysis for protein crystallization and structure determination.
Nat.Methods, 4, 2007
2QFZ
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CRYSTAL STRUCTURE OF HUMAN TBC1 DOMAIN FAMILY MEMBER 22A
分子名称:TBC1 domain family member 22A, UNKNOWN ATOM OR ION
著者Tong, Y., Tempel, W., Dimov, S., Dong, A., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-06-28
公開日2007-07-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human TBC1 domain family member 22A.
To be Published
2QQ8
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CRYSTAL STRUCTURE OF THE PUTATIVE RABGAP DOMAIN OF HUMAN TBC1 DOMAIN FAMILY MEMBER 14
分子名称:TBC1 domain family member 14, UNKNOWN ATOM OR ION
著者Tong, Y., Tempel, W., Dimov, S., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-07-26
公開日2007-08-07
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14.
To be Published
2R2O
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CRYSTAL STRUCTURE OF THE EFFECTOR DOMAIN OF HUMAN PLEXIN B1
分子名称:Plexin-B1, UNKNOWN ATOM OR ION
著者Tong, Y., Tempel, W., Shen, L., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-08-27
公開日2007-09-04
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.
J.Biol.Chem., 282, 2007
2R79
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CRYSTAL STRUCTURE OF A PERIPLASMIC HEME BINDING PROTEIN FROM PSEUDOMONAS AERUGINOSA
分子名称:Periplasmic binding protein, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ho, W.W., Li, H., Poulos, T.L.
登録日2007-09-07
公開日2007-10-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
2R7A
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CRYSTAL STRUCTURE OF A PERIPLASMIC HEME BINDING PROTEIN FROM SHIGELLA DYSENTERIAE
分子名称:Bacterial heme binding protein, PROTOPORPHYRIN IX CONTAINING FE
著者Ho, W.W., Li, H., Poulos, T.L.
登録日2007-09-07
公開日2007-10-09
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
2REX
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CRYSTAL STRUCTURE OF THE EFFECTOR DOMAIN OF PLXNB1 BOUND WITH RND1 GTPASE
分子名称:Plexin-B1, Rho-related GTP-binding protein Rho6, UNKNOWN ATOM OR ION, ...
著者Tong, Y., Tempel, W., Shen, L., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-11-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published
2RG7
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APO- CRYSTAL STRUCTURE OF A PERIPLASMIC HEME BINDING PROTEIN FROM SHIGELLA DYSENTERIAE
分子名称:Periplasmic HEME binding protein
著者Ho, W.W., Li, H.
登録日2007-10-02
公開日2007-10-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
3C5C
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CRYSTAL STRUCTURE OF HUMAN RAS-LIKE, FAMILY 12 PROTEIN IN COMPLEX WITH GDP
分子名称:RAS-like protein 12, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Shen, L., Tong, Y., Tempel, W., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of human Ras-like, family 12 protein in complex with GDP.
To be Published
3C5H
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CRYSTAL STRUCTURE OF THE RAS HOMOLOG DOMAIN OF HUMAN GRLF1 (P190RHOGAP)
分子名称:Glucocorticoid receptor DNA-binding factor 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP).
To be Published