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6YSF
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BU of 6ysf by Molmil
Structure of the flagellar MotAB stator complex from Clostridium sporogenes
Descriptor: Chemotaxis MotA protein, Chemotaxis motB protein
Authors:Lea, S.M, Deme, J.C, Johnson, S.J.
Deposit date:2020-04-22
Release date:2020-08-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the stator complex that drives rotation of the bacterial flagellum.
Nat Microbiol, 5, 2020
6YSL
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BU of 6ysl by Molmil
Structure of the flagellar MotAB stator complex from Bacillus subtilis
Descriptor: Motility protein A, Motility protein B
Authors:Lea, S.M, Deme, J.C, Johnson, S.J.
Deposit date:2020-04-22
Release date:2020-08-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the stator complex that drives rotation of the bacterial flagellum.
Nat Microbiol, 5, 2020
8FY4
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BU of 8fy4 by Molmil
Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
Authors:Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E.
Deposit date:2023-01-25
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
8FY3
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BU of 8fy3 by Molmil
Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
Authors:Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E.
Deposit date:2023-01-25
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
7B29
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BU of 7b29 by Molmil
Complement inhibitor CirpA4 from Rhipicephalus appendiculatus
Descriptor: CADMIUM ION, CHLORIDE ION, CirpA4
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2A
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BU of 7b2a by Molmil
Complement inhibitor CirpA5 from Rhipicephalus appendiculatus
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CirpA5
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2D
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BU of 7b2d by Molmil
Complement inhibitor CirpA1 from Rhipicephalus pulchellus
Descriptor: CirpA1, D-MALATE
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B26
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BU of 7b26 by Molmil
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Descriptor: CirpA1, Properdin, alpha-D-mannopyranose, ...
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B28
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BU of 7b28 by Molmil
Complement inhibitor CirpA3 from Rhipicephalus pulchellus
Descriptor: CirpA3, SULFATE ION
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
6SD6
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BU of 6sd6 by Molmil
Structure of VapBC from Shigella sonnei
Descriptor: Antitoxin, tRNA(fMet)-specific endonuclease VapC
Authors:Lea, S.M, Hollingshead, S.
Deposit date:2019-07-26
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei
To Be Published
7NVG
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BU of 7nvg by Molmil
Salmonella flagellar basal body refined in C1 map
Descriptor: Basal-body rod modification protein FlgD, Flagellar L-ring protein, Flagellar M-ring protein, ...
Authors:Johnson, S, Furlong, E, Lea, S.M.
Deposit date:2021-03-15
Release date:2021-05-05
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular structure of the intact bacterial flagellar basal body.
Nat Microbiol, 6, 2021
7NVH
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BU of 7nvh by Molmil
Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis
Descriptor: Lauryl Maltose Neopentyl Glycol, Trehalose monomycolate exporter MmpL3
Authors:Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S.
Deposit date:2021-03-15
Release date:2021-06-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target.
Structure, 29, 2021
6F2D
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BU of 6f2d by Molmil
A FliPQR complex forms the core of the Salmonella type III secretion system export apparatus.
Descriptor: Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR
Authors:Johnson, S, Kuhlen, L, Abrusci, P, Lea, S.M.
Deposit date:2017-11-24
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the core of the type III secretion system export apparatus.
Nat. Struct. Mol. Biol., 25, 2018
2XRC
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BU of 2xrc by Molmil
Human complement factor I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HUMAN COMPLEMENT FACTOR I
Authors:Roversi, P, Johnson, S, Lea, S.M.
Deposit date:2010-09-13
Release date:2011-07-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms.
Proc.Natl.Acad.Sci.USA, 108, 2011
1H2Q
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BU of 1h2q by Molmil
Human CD55 domains 3 & 4
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR
Authors:Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Powell, R, Spiller, O.B, Evans, D.J, Lea, S.M.
Deposit date:2002-08-13
Release date:2003-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
7SB2
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BU of 7sb2 by Molmil
Structure of the periplasmic domain of GldM from Capnocytophaga canimorsus
Descriptor: GldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
7SAT
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BU of 7sat by Molmil
Structure of PorLM, the proton-powered motor that drives Type IX protein secretion
Descriptor: Por secretion system protein porL/gldL, Por secretion system protein porM/gldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
7SAZ
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BU of 7saz by Molmil
Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Capnocytophaga canimorsus
Descriptor: GldL, GldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
7SAU
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BU of 7sau by Molmil
Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Schleiferia thermophila
Descriptor: GldM, Gliding motility protein GldL
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
7SAX
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BU of 7sax by Molmil
Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Sphingobacterium wenxiniae
Descriptor: GldL, GldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
4CUD
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BU of 4cud by Molmil
Human Notch1 EGF domains 11-13 mutant fucosylated at T466
Descriptor: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, alpha-L-fucopyranose
Authors:Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CVX
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BU of 4cvx by Molmil
COMPLEX OF A B2 CHICKEN MHC CLASS I MOLECULE AND A 9MER CHICKEN PEPTIDE
Descriptor: BETA-2-MICROGLOBULIN, MHC CLASS I ALPHA CHAIN 2, SELF-PEPTIDE
Authors:Chappell, P.E, Roversi, P, Harrison, M.C, Mears, L.E, Kaufman, J.F, Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4D0F
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BU of 4d0f by Molmil
Human Notch1 EGF domains 11-13 mutant T466A
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A.
Deposit date:2014-04-25
Release date:2014-05-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CUE
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BU of 4cue by Molmil
Human Notch1 EGF domains 11-13 mutant T466V
Descriptor: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CW1
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BU of 4cw1 by Molmil
COMPLEX OF A B14 CHICKEN MHC CLASS I MOLECULE AND A 9MER CHICKEN PEPTIDE
Descriptor: BETA-2-MICROGLOBULIN, MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14, PEPTIDE
Authors:Chappell, P.E, Roversi, P, Harrison, M.C, Mears, L.E, Kaufman, J.F, Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015

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